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ULBP1 Proteine (ULBP1)

Bezeichnung:
UL16 Binding Protein 1 Proteine (ULBP1)
Auf www.antikoerper-online.de finden Sie aktuell 12 UL16 Binding Protein 1 (ULBP1) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ULBP1 Antikörper (53) und ULBP1 Kits (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 82 ULBP1 Produkte verfügbar.
Synonyme:
A430108B07Rik, MULT1, RAET1I
alle Proteine anzeigen Gen GeneID UniProt
ULBP1 80329 Q9BZM6
ULBP1 77777  

Weitere Synonyme anzeigen

ULBP1 Proteine (ULBP1) nach Spezies

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Am meisten referenzierte ULBP1 Proteine

  1. Human ULBP1 Protein expressed in Escherichia coli (E. coli) - ABIN1098403 : Bacon, Eagle, Meyer, Easom, Young, Trowsdale: Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Zeige alle 2 Referenzen für ABIN1098403

Weitere Proteine zu ULBP1 Interaktionspartnern

Human UL16 Binding Protein 1 (ULBP1) Interaktionspartner

  1. ATF4 (zeige ATF4 Proteine) drives ULBP1 gene expression in cancer cell lines, while the RNA-binding protein (zeige PTBP1 Proteine) RBM4 (zeige RBM4 Proteine) supports ULBP1 expression by suppressing a novel alternatively spliced isoform of ULBP1 mRNA.

  2. expression determines intrinsic acute myeloid leukemia (zeige BCL11A Proteine) susceptibility to allogeneic V[gamma]9V[delta]2 T cells

  3. This study provides for the first time, the c-Myc (zeige MYC Proteine) dependent regulation of NKG2D (zeige KLRK1 Proteine) ligands, ULBP1/2/3 in acute myeloid leukemia (zeige BCL11A Proteine).

  4. recurrence-free survival of patients with ULBP1-negative hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) was significantly shorter than that of patients with ULBP1-positive HCC (zeige FAM126A Proteine)

  5. Findings define the involvement of p53 (zeige TP53 Proteine) in the regulation of ULBP1 and ULBP2 (zeige ULBP2 Proteine) which enhance NK cell-mediated target recognition.

  6. recombinant ULBP1 fused to CD45 (zeige PTPRC Proteine) caused a reduction in cytotoxicity and degranulation by NK cells, implying a role for receptor ligand distribution in the activation of NK cell responses

  7. Data show that ULBP1, TFR2 (zeige TFR2 Proteine) and IFITM1 (zeige IFITM1 Proteine) were associated with increased susceptibility to Vgamma9Vdelta2 T-cell cytotoxicity.

  8. These results identify Mult1 as a target for the MARCH family of E3 ligases

  9. As NKG2D (zeige KLRK1 Proteine) ligand, ULBP1 are expressed on immature dendritic cells and plays an important role in the cytotoxic effect of NK cells against iDC (zeige LMNA Proteine).

  10. Data show that the protease NS3/4A of HCV down-regulates ULBP1 expression by inhibiting the transcription of ULBP1.

Mouse (Murine) UL16 Binding Protein 1 (ULBP1) Interaktionspartner

  1. The results show that NK cells and the NKG2D (zeige KLRK1 Proteine) receptor play a role in control of lymphomas, and that selection of NKG2D (zeige KLRK1 Proteine)-ligand (MULT1) loss mutants provides a mechanism for tumor escape.

  2. An increased expression of the NKG2D (zeige KLRK1 Proteine) ligand MICA (zeige MICA Proteine) in systemic lupus erthematosus (SLE) patients' kidneys and Rae-1 (zeige RAE1 Proteine) and Mult-1 in various murine SLE models, is reported.

  3. These results identify Mult1 as a target for the MARCH family of E3 ligases

  4. MULT1 (UL16-binding protein-like transcript 1) is expressed in adult parenchyma, possesses MHC class I-like alpha 1 and alpha 2 domains and a large cytoplasmic domain, and binds NKG2D (zeige KLRK1 Proteine) with high affinity. (MULT1)

  5. Mouse cytomegalovirus (MCMV) molecule fcr-1 promotes a rapid down-regulation of NKG2D (zeige KLRK1 Proteine) ligands murine UL16-binding protein like transcript (MULT)-1 and H60 from the cell surface.

Pig (Porcine) UL16 Binding Protein 1 (ULBP1) Interaktionspartner

  1. ULBP1 is the predominant, if not only, functional porcine ligand for human natural killer (NK) cell activating receptor (zeige NCR1 Proteine) NKG2D (zeige KLRK1 Proteine); if eliminated on porcine tissues ULBP1 represents an attractive target to protect porcine xenografts from human NK cytotoxicity.

ULBP1 Protein Überblick

Protein Überblick

Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis- Golgi apparatus so that it does not reach the cell surface.

Alternative names and synonyms associated with ULBP1

  • UL16 binding protein 21 (ULBP21)
  • UL16 binding protein 1 (ULBP1)
  • UL16 binding protein 1 (Ulbp1)
  • A430108B07Rik Protein
  • MULT1 Protein
  • RAET1I Protein

Bezeichner auf Proteinebene für UL16 Binding Protein 1 Proteine (ULBP1)

UL16 binding protein 1 , N2DL-1 , NKG2D ligand 1 , NKG2DL1 , UL16-binding protein 1 , alcan-beta , retinoic acid early transcript 1I , UL16-binding protein-like transcript 1 , NK cell receptor ligand

GENE ID SPEZIES
513308 Bos taurus
735443 Pan troglodytes
80329 Homo sapiens
77777 Mus musculus
445523 Sus scrofa
785237 Bos taurus
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