ADRBK2 Proteine (ADRBK2)

Adrenergic, Beta, Receptor Kinase 2 Proteine (ADRBK2)
Auf finden Sie aktuell 9 Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ADRBK2 Antikörper (107) und ADRBK2 Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 123 ADRBK2 Produkte verfügbar.
4833444A01Rik, Adrbk-2, AI851927, AW551196, Bark-2, BARK2, Grk3, si:dz221d18.1
alle Proteine anzeigen Gen GeneID UniProt
ADRBK2 320129 Q3UYH7
ADRBK2 157 P35626
ADRBK2 25372 P26819

Weitere Synonyme anzeigen

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Weitere Proteine zu ADRBK2 Interaktionspartnern

Mouse (Murine) Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) Interaktionspartner

  1. GRK3 controls cardiac alpha1-adrenergic receptor responsiveness

Human Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) Interaktionspartner

  1. effects of GRK3 modulation appear to be specific to chemokine (zeige CCL1 Proteine)-mediated migration behaviors without influencing tumor cell proliferation or survival

  2. data are consistent with the possibility that oncogenes can induce cellular stiffness via an HDAC6 (zeige HDAC6 Proteine)-induced reorganization of the vimentin (zeige VIM Proteine) intermediate filament network

  3. Data indicate that CXCL12 (zeige CXCL12 Proteine)-induced phosphorylation at CXCR4 (zeige CXCR4 Proteine) S346/347 was mediated by GRK2/3.

  4. In oral squamous cell carcinomas, malignant cells and surrounding tissue overexpress the ADRBK2 gene.

  5. A reduced cortical concentration of GRK3 in schizophrenia (resembling that in aging) may result in altered G protein-dependent signaling, thus contributing to prefrontal deficits in schizophrenia.

  6. GRK3 is a negative regulator of cell growth whose expression is preferentially reduced in glioblastoma of the classical subtype as a consequence of activity in primary gliomagenic pathways.

  7. mRNA levels for GRK3 were inversely correlated with systolic and diastolic blood pressure (day, night and 24 h), which suggests a protective role for GRK3 in the regulation of human blood pressure

  8. we found no evidence of altered levels of acetylated histone H3 (zeige HIST3H3 Proteine) at the affected allele compared to the common allele

  9. dysregulation in GRK3 expression alters signaling desensitization, and thereby predisposes to the development of bipolar disorder

  10. the CRH (zeige CRH Proteine)-R1alpha carboxyl tail is important for regulation of receptor activity by G protein-coupled receptor (zeige ADRA1A Proteine) kinase

Zebrafish Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) Interaktionspartner

  1. beta-arrestin 2 (zeige ARRB2 Proteine) and GRK2 (zeige ADRBK1 Proteine) colocalize with S1p2 (zeige S1PR2 Proteine) in developing zebrafish embryos and depletion of GRK2 (zeige ADRBK1 Proteine) in the S1p2 (zeige S1PR2 Proteine) R150H miles apart zebrafish partially rescued cardia bifida.

  2. GRK2 (zeige ADRBK1 Proteine) and GRK5 (zeige GRK5 Proteine) control cardiac function as well as morphogenesis during development although with different morphological outcomes.

  3. Data suggest that a G protein-coupled receptor (zeige GPBAR1 Proteine) kinase, perhaps GRK2 (zeige ADRBK1 Proteine) or 3, functions as a vertebrate kinase for Smoothened, promoting Hedgehog (zeige SHH Proteine) signal transduction during early development.

  4. These data thus reveal a novel kinase activity-independent function for GRK and establish a role for GRK2 as a cell-cycle regulator during early embryonic development.

Cow (Bovine) Adrenergic, Beta, Receptor Kinase 2 (ADRBK2) Interaktionspartner

  1. Fusion proteins containing the c-terminus of GPCR kinase 3 (GRK3ct) and either the fluorescent protein cerulean or Renilla luciferase bind to venus-labeled Gbetagamma dimers, resulting in Forster or bioluminescence resonance energy transfer.

ADRBK2 Protein Überblick

Protein Überblick

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

Alternative names and synonyms associated with ADRBK2

  • adrenergic, beta, receptor kinase 2 (ADRBK2)
  • adrenergic, beta, receptor kinase 2 (adrbk2)
  • adrenergic receptor kinase, beta 2 (Adrbk2)
  • adrenergic, beta, receptor kinase 2 (Adrbk2)
  • 4833444A01Rik Protein
  • Adrbk-2 Protein
  • AI851927 Protein
  • AW551196 Protein
  • Bark-2 Protein
  • BARK2 Protein
  • Grk3 Protein
  • si:dz221d18.1 Protein

Bezeichner auf Proteinebene für ADRBK2

adrenergic, beta, receptor kinase 2 , beta-adrenergic receptor kinase 2-like , beta ARK2 , beta-ARK-2 , beta-adrenergic receptor kinase 2 , G-protein-coupled receptor kinase 3 , adrenergic receptor kinase, beta 2 (G-protein-linked receptor kinase) , G-protein coupled receptor kinase 2/3 , GRK2/3

486327 Canis lupus familiaris
100065495 Equus caballus
100379889 Xenopus (Silurana) tropicalis
100396838 Callithrix jacchus
714510 Macaca mulatta
100156449 Sus scrofa
100614029 Pan troglodytes
320129 Mus musculus
157 Homo sapiens
25372 Rattus norvegicus
569403 Danio rerio
416904 Gallus gallus
282136 Bos taurus
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