ULK1 Proteine (ULK1)

Auf www.antikoerper-online.de finden Sie aktuell 15 Unc-51 Like Kinase 1 (C. Elegans) (ULK1) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ULK1 Antikörper (260) und ULK1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 289 ULK1 Produkte verfügbar.
Synonyme:
ATG1, ATG1A, AU041434, hATG1, mKIAA0722, si:dkey-11o18.7, ulk1, UNC51, Unc51.1
alle Proteine anzeigen Gen GeneID UniProt
ULK1 8408 O75385
Ratte ULK1 ULK1 360827  
Maus ULK1 ULK1 22241 O70405

ULK1 Proteine (ULK1) nach Spezies

Weitere Proteine zu ULK1 Interaktionspartnern

Human Unc-51 Like Kinase 1 (C. Elegans) (ULK1) Interaktionspartner

  1. These findings reveal that Endoplasmic reticulum stress engages the GSK3beta-TIP60 (zeige KAT5 Proteine)-ULK1 pathway to increase autophagy.

  2. ULK1/2 function as a bifurcate-signaling node that sustains glucose metabolic fluxes besides initiation of autophagy in response to nutritional deprivation.

  3. these results demonstrate the effective anti-autophagic of NRAGE (zeige MAGED1 Proteine) in non-small-cell lung cancer cells through AMPK (zeige PRKAA1 Proteine)/Ulk1/Atg13 (zeige ATG13 Proteine) autophagy signaling pathways. Therefore, NRAGE (zeige MAGED1 Proteine) could be used as a potential therapeutic target for lung cancer.

  4. results from western blotting assays and immunoprecipitation assays displayed that sirtuin 6 (zeige SIRT6 Proteine) specifically interacted with ULK1 and positively regulated its activity by inhibiting its upstream factor mammalian target of rapamycin (zeige FRAP1 Proteine) activity.

  5. As a Rab1a (zeige RAB1A Proteine) effector, C9orf72 (zeige C9ORF72 Proteine) controls initiation of autophagy by regulating the Rab1a (zeige RAB1A Proteine)-dependent trafficking of the ULK1 autophagy initiation complex to the phagophore.

  6. Ulk1 promoted the degradation of Hsp90 (zeige HSP90 Proteine)-Cdc37 (zeige CDC37 Proteine) client kinases, resulting in increased cellular sensitivity to Hsp90 (zeige HSP90 Proteine) inhibitors. Thus, our study provides evidence for an anti-proliferative role of Ulk1 in response to Hsp90 (zeige HSP90 Proteine) inhibition in cancer cells

  7. Here, the authors demonstrate that S100A10 (zeige S100A10 Proteine) is required for ULK1 localization to autophagosome formation sites. Silencing of S100A10 (zeige S100A10 Proteine) reduces IFN-gamma-induced (zeige SAMHD1 Proteine) autophagosome formation.

  8. A strong association of rs12297124, a noncoding ULK1 SNP, with LTBI and a role for ULK1 regulation of TNF (zeige TNF Proteine) secretion.

  9. High expression of ULK1 concomitant with high expression of LRPPRC (zeige LRPPRC Proteine) may serve as useful markers for shorter biochemical progression (BCP (zeige OPN1SW Proteine))-free survival and overall survival in patients with metastatic prostate cancer (PCa (zeige FLVCR1 Proteine)) after androgen deprivation therapy (ADT).

  10. These results thus place NEDD4L (zeige NEDD4L Proteine) and ULK1 in a key position to control oscillatory activation of autophagy during prolonged stress to keep the levels of this process under a safe and physiological threshold.

Mouse (Murine) Unc-51 Like Kinase 1 (C. Elegans) (ULK1) Interaktionspartner

  1. ULK1 is a novel substrate of Caspase-3 (zeige CASP3 Proteine) and upregulation of ULK1 drives autophagy initiation in leukemia cells.

  2. Findings indicate that the PPM1D (zeige PPM1D Proteine)-Ulk1 axis plays a pivotal role in genotoxic stress-induced autophagy.

  3. Regulation of endoplasmic reticulum-to-Golgi trafficking by ULK1/2 is essential for cellular homeostasis.

  4. Ulk1-mediated autophagy plays an essential role in mitochondrial remodeling and functional regeneration of skeletal muscle.

  5. ULK1/2 function as a bifurcate-signaling node that sustains glucose metabolic fluxes besides initiation of autophagy in response to nutritional deprivation.

  6. These results demonstrate a novel mechanism by which STAT1 (zeige STAT1 Proteine) negatively regulates ULK1 expression and autophagy.

  7. These results define a key molecular event for the starvation-induced activation of the ATG14-containing PtdIns3K complex by ULK1.

  8. By enhancing PARP1 (zeige PARP1 Proteine) activity, ULK1 contributes to ATP depletion and death of H2O2-treated cells.

  9. MUL1 (zeige MUL1 Proteine) ubiquitinates ULK1 and regulates selenite-induced mitophagy

  10. autophagy can be executed by mechanisms that are dependent or independent of the ULK1/2-ATG13 (zeige ATG13 Proteine) interaction.

ULK1 Protein Überblick

Protein Überblick

predicted to have similarity to C. elegans serine/threonine kinase UNC-51

Alternative names and synonyms associated with ULK1

  • unc-51-like kinase 1 (C. elegans) (ULK1)
  • unc-51-like kinase 1b (C. elegans) (ulk1b)
  • unc-51 like autophagy activating kinase 1 (ULK1)
  • unc-51 like autophagy activating kinase 1 (Ulk1)
  • unc-51 like kinase 1 (Ulk1)
  • ATG1 Protein
  • ATG1A Protein
  • AU041434 Protein
  • hATG1 Protein
  • mKIAA0722 Protein
  • si:dkey-11o18.7 Protein
  • ulk1 Protein
  • UNC51 Protein
  • Unc51.1 Protein

Bezeichner auf Proteinebene für ULK1

unc-51-like kinase 1 (C. elegans) , serine/threonine-protein kinase ULK1 , unc-51-like kinase 1 , ATG1 autophagy related 1 homolog , autophagy-related protein 1 homolog , serine/threonine-protein kinase Unc51.1

GENE ID SPEZIES
416800 Gallus gallus
477437 Canis lupus familiaris
526310 Bos taurus
558848 Danio rerio
744289 Pan troglodytes
100062311 Equus caballus
8408 Homo sapiens
360827 Rattus norvegicus
22241 Mus musculus
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