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ULK1 Proteine (ULK1)

Bezeichnung:
Unc-51 Like Kinase 1 (C. Elegans) Proteine (ULK1)
Auf www.antikoerper-online.de finden Sie aktuell 15 Unc-51 Like Kinase 1 (C. Elegans) (ULK1) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ULK1 Antikörper (259) und ULK1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 288 ULK1 Produkte verfügbar.
Synonyme:
ATG1, ATG1A, AU041434, hATG1, mKIAA0722, si:dkey-11o18.7, ulk1, UNC51, Unc51.1
alle Proteine anzeigen Gen GeneID UniProt
ULK1 8408 O75385
Ratte ULK1 ULK1 360827  
Maus ULK1 ULK1 22241 O70405

Weitere Synonyme anzeigen

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Weitere Proteine zu ULK1 Interaktionspartnern

Human Unc-51 Like Kinase 1 (C. Elegans) (ULK1) Interaktionspartner

  1. these results demonstrate the effective anti-autophagic of NRAGE (zeige MAGED1 Proteine) in non-small-cell lung cancer cells through AMPK (zeige PRKAA1 Proteine)/Ulk1/Atg13 (zeige ATG13 Proteine) autophagy signaling pathways. Therefore, NRAGE (zeige MAGED1 Proteine) could be used as a potential therapeutic target for lung cancer.

  2. results from western blotting assays and immunoprecipitation assays displayed that sirtuin 6 (zeige SIRT6 Proteine) specifically interacted with ULK1 and positively regulated its activity by inhibiting its upstream factor mammalian target of rapamycin (zeige FRAP1 Proteine) activity.

  3. As a Rab1a (zeige RAB1A Proteine) effector, C9orf72 (zeige C9ORF72 Proteine) controls initiation of autophagy by regulating the Rab1a (zeige RAB1A Proteine)-dependent trafficking of the ULK1 autophagy initiation complex to the phagophore.

  4. Ulk1 promoted the degradation of Hsp90 (zeige HSP90 Proteine)-Cdc37 (zeige CDC37 Proteine) client kinases, resulting in increased cellular sensitivity to Hsp90 (zeige HSP90 Proteine) inhibitors. Thus, our study provides evidence for an anti-proliferative role of Ulk1 in response to Hsp90 (zeige HSP90 Proteine) inhibition in cancer cells

  5. Here, the authors demonstrate that S100A10 (zeige S100A10 Proteine) is required for ULK1 localization to autophagosome formation sites. Silencing of S100A10 (zeige S100A10 Proteine) reduces IFN-gamma-induced (zeige SAMHD1 Proteine) autophagosome formation.

  6. A strong association of rs12297124, a noncoding ULK1 SNP, with LTBI and a role for ULK1 regulation of TNF (zeige TNF Proteine) secretion.

  7. High expression of ULK1 concomitant with high expression of LRPPRC (zeige LRPPRC Proteine) may serve as useful markers for shorter biochemical progression (BCP (zeige OPN1SW Proteine))-free survival and overall survival in patients with metastatic prostate cancer (PCa (zeige FLVCR1 Proteine)) after androgen deprivation therapy (ADT).

  8. These results thus place NEDD4L (zeige NEDD4L Proteine) and ULK1 in a key position to control oscillatory activation of autophagy during prolonged stress to keep the levels of this process under a safe and physiological threshold.

  9. These results demonstrate a novel mechanism by which STAT1 (zeige STAT1 Proteine) negatively regulates ULK1 expression and autophagy.

  10. These results show that the SiMoA technology can detect quantitatively low levels of endogenous biomarkers with the ability to detect the loss of pSer(318)-Atg13 (zeige ATG13 Proteine) upon ULK1 inhibition.

Mouse (Murine) Unc-51 Like Kinase 1 (C. Elegans) (ULK1) Interaktionspartner

  1. These results demonstrate a novel mechanism by which STAT1 (zeige STAT1 Proteine) negatively regulates ULK1 expression and autophagy.

  2. These results define a key molecular event for the starvation-induced activation of the ATG14-containing PtdIns3K complex by ULK1.

  3. By enhancing PARP1 (zeige PARP1 Proteine) activity, ULK1 contributes to ATP depletion and death of H2O2-treated cells.

  4. MUL1 (zeige MUL1 Proteine) ubiquitinates ULK1 and regulates selenite-induced mitophagy

  5. autophagy can be executed by mechanisms that are dependent or independent of the ULK1/2-ATG13 (zeige ATG13 Proteine) interaction.

  6. MiR-17-5p may be able to arrest the maturation of mycobacterial phagosomes in part by targeting ULK1, subsequently reduces the ability of host cells to kill intracellular Camette-Guerin bacillus.

  7. Study identifies a key role of Cul3 (zeige CUL3 Proteine)-KLHL20 (zeige KLHL20 Proteine) in autophagy termination by controlling autophagy-dependent turnover of ULK1 and VPS34 (zeige PIK3C3 Proteine) complex subunits and reveals the pathophysiological functions of this autophagy termination mechanism.

  8. Concurrent mTORC1 inactivation and PP2A (zeige PPP2R2B Proteine)-B55alpha (zeige PPP2R2A Proteine) stimulation fuel ULK1-dependent autophagy.

  9. AnxA2 (zeige ANXA2 Proteine) regulates autophagy, thereby contributing to host immunity against bacteria through the Akt1 (zeige AKT1 Proteine)-mTOR (zeige FRAP1 Proteine)-ULK1/2 signaling pathway

  10. Nitric oxide also stabilized an autophagy-related protein unc-51 like kinase (ULK1), but did not restore SIRT1 (zeige SIRT1 Proteine) protein levels in ULK1-siRNA-treated cells or in mouse embryonic fibroblasts (MEF) from Ulk1-/- mice.

ULK1 Protein Überblick

Protein Überblick

predicted to have similarity to C. elegans serine/threonine kinase UNC-51

Alternative names and synonyms associated with ULK1

  • unc-51-like kinase 1 (C. elegans) (ULK1)
  • unc-51-like kinase 1b (C. elegans) (ulk1b)
  • unc-51 like autophagy activating kinase 1 (ULK1)
  • unc-51 like autophagy activating kinase 1 (Ulk1)
  • unc-51 like kinase 1 (Ulk1)
  • ATG1 Protein
  • ATG1A Protein
  • AU041434 Protein
  • hATG1 Protein
  • mKIAA0722 Protein
  • si:dkey-11o18.7 Protein
  • ulk1 Protein
  • UNC51 Protein
  • Unc51.1 Protein

Bezeichner auf Proteinebene für ULK1

unc-51-like kinase 1 (C. elegans) , serine/threonine-protein kinase ULK1 , unc-51-like kinase 1 , ATG1 autophagy related 1 homolog , autophagy-related protein 1 homolog , serine/threonine-protein kinase Unc51.1

GENE ID SPEZIES
416800 Gallus gallus
477437 Canis lupus familiaris
526310 Bos taurus
558848 Danio rerio
744289 Pan troglodytes
100062311 Equus caballus
8408 Homo sapiens
360827 Rattus norvegicus
22241 Mus musculus
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