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Neuropilin 1 Proteine (NRP1)

Neuropilin 1 Proteine (NRP1)
Auf finden Sie aktuell 37 Neuropilin 1 (NRP1) Proteine von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Neuropilin 1 Antikörper (278) und Neuropilin 1 Kits (43) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 377 Neuropilin 1 Produkte verfügbar.
BDCA4, C530029I03, CD304, neuropilin, NP-1, NP1, NPN-1, Npn1, Nrp, nrp-1, NRP1, VEGF165R
alle Proteine anzeigen Gen GeneID UniProt
NRP1 8829 O14786
NRP1 18186 P97333
NRP1 246331 Q9QWJ9

Weitere Synonyme anzeigen

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Am meisten referenzierte Neuropilin 1 Proteine

  1. Human Neuropilin 1 Protein expressed in Human Cells - ABIN2001892 : He, Tessier-Lavigne: Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. in Cell 1997 (PubMed)
    Zeige alle 7 Referenzen für ABIN2001892

  2. Human Neuropilin 1 Protein expressed in Human Cells - ABIN2001890 : Soker, Takashima, Miao, Neufeld, Klagsbrun: Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. in Cell 1998 (PubMed)
    Zeige alle 5 Referenzen für ABIN2001890

  3. Cynomolgus Neuropilin 1 Protein expressed in Human Cells - ABIN2010114 : Schuch, Machluf, Bartsch, Nomi, Richard, Atala, Soker: In vivo administration of vascular endothelial growth factor (VEGF) and its antagonist, soluble neuropilin-1, predicts a role of VEGF in the progression of acute myeloid leukemia in vivo. in Blood 2002 (PubMed)
    Zeige alle 5 Referenzen für ABIN2010114

  4. Human Neuropilin 1 Protein expressed in HEK-293 Cells - ABIN2181550 : Tamagnone, Artigiani, Chen, He, Ming, Song, Chedotal, Winberg, Goodman, Poo, Tessier-Lavigne, Comoglio: Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates. in Cell 1999 (PubMed)
    Zeige alle 2 Referenzen für ABIN2181550

Weitere Proteine zu Neuropilin 1 Interaktionspartnern

Human Neuropilin 1 (NRP1) Interaktionspartner

  1. this study shows that NRP1 (zeige NELL1 Proteine) can act as a co-receptor for PDGF-D (zeige PDGFD Proteine)-PDGFRbeta signaling and is possibly implicated in intercellular communication in the vascular wall

  2. This review provides a general overview of current knowledge of the signalling pathways that are modulated by NRP1 (zeige NELL1 Proteine), with particular focus on neuronal and vascular roles in the brain and retina.

  3. This study suggests that NRP1 (zeige NELL1 Proteine) expression and LVD are independent factors that are likely to predict the risk of LN metastasis in squamous cell carcinoma (SCC (zeige CYP11A1 Proteine))of the tongue, whereas the expression of VEGFC (zeige VEGFC Proteine), VEGFR3 (zeige FLT4 Proteine), CCR7 (zeige CCR7 Proteine), and SEMA3E (zeige SEMA3E Proteine) are nonindependent predictive factors

  4. Curcumin-loaded nanoliposomes linked to homing peptides for integrin targeting and neuropilin-1-mediated internalization reduced viability of breast cancer cells.

  5. Upregulated expression of NRP1 (zeige NELL1 Proteine) is associated with glioma.

  6. Studies suggest that the activation of NRP-1 (zeige NELL1 Proteine) by PlGF (zeige PGF Proteine) directly contributes to tumour aggressiveness and to melanoma escape from anti-VEGF-A (zeige VEGFA Proteine) therapies.

  7. REVIEW: Nrp1 (zeige NELL1 Proteine) functions in the vasculature is critical for the development of targeted therapeutics for cancer and vascular diseases such as atherosclerosis and retinopathies.

  8. High Expression of Neuropilin-1 Associates with Hepatocellular Carcinoma.

  9. Increased NRP-1 (zeige NELL1 Proteine) expression is associated with metastatic endometrial and lung cancers.

  10. miR (zeige MLXIP Proteine)-152 suppression in NSCLC cells might promote neuropilin-1 mediated cancer metastasis.

Mouse (Murine) Neuropilin 1 (NRP1) Interaktionspartner

  1. IL-10 (zeige IL10 Proteine) abrogation efficiently induces regulatory T cell (Treg) formation but dampens tumoral neuropilin-1 (Nrp-1) Treg signaling, which simultaneously augments Th1 (zeige HAND1 Proteine) and Th17 immunity.

  2. that microglial expression of Neuropilin-1 (Nrp1) is required for tuftsin-driven amelioration of EAE symptoms

  3. Sepsis per se markedly promoted the expression of Nrp-1 of CD4 (zeige CD4 Proteine)(+)CD25 (zeige IL2RA Proteine)(+)Tregs. Foxp-3 (zeige FOXP3 Proteine)/CTLA-4 (zeige CTLA4 Proteine)/TGF-beta (zeige TGFB1 Proteine)(m+) of Nrp-1(high)Tregs were upregulated by septic challenge.

  4. Both placental NRP1 and VEGF were expressed at lower levels in women with pre-eclampsia and homocysteine-treated mice, which may contribute to endothelial damage.

  5. suppression of beta3-integrin (zeige ITGB3 Proteine) in mice leads to the activation of a neuropilin-1 (NRP1)-dependent cell migration pathway in endothelial cells via a mechanism that depends on NRP1's mobilisation away from mature focal adhesions following VEGF (zeige VEGFA Proteine)-stimulation

  6. The results show that high vs. low expression of Nrp-1 or Helios (zeige ZNFN1A2 Proteine) does not unequivocally identify Treg clones of thymic or peripheral origin.

  7. Nrp1 in endothelial cells suppresses TGFbeta (zeige TGFB1 Proteine) activation and signaling by forming intercellular protein complexes with beta8 integrin.

  8. In vascular sprouting, neuropilin-1 suppresses the stalk-cell phenotype by limiting Smad2 (zeige SMAD2 Proteine)/3 activation through Alk1 (zeige ACVRL1 Proteine) and Alk5 (zeige TGFBR1 Proteine). Notch (zeige NOTCH1 Proteine) downregulates Nrp1, thus relieving the inhibition of Alk1 (zeige ACVRL1 Proteine) and Alk5 (zeige TGFBR1 Proteine), thereby driving stalk-cell behaviour.

  9. NRP1 enables ECM (zeige MMRN1 Proteine)-induced filopodia formation for tip cell function during sprouting angiogenesis.

  10. demonstrate that in mice on the C57Bl/6 background EMX1 (zeige EMX1 Proteine) plays an essential role in the midline crossing of an axonal subpopulation of the corpus callosum derived from the anterior cingulate cortex. In the absence of EMX1 (zeige EMX1 Proteine), cingulate axons display reduced expression of the axon guidance receptor NRP1 and form aberrant axonal bundles within the rostral corpus callosum.

Xenopus laevis Neuropilin 1 (NRP1) Interaktionspartner

  1. Neuropilin-1 and its co-receptor plexinA1 (zeige PLXNA1 Proteine) are necessary to bias the extension of the dendrites of retinal ganglion cells to the apical side of the cell, and ectopically expressed class III semaphorins (Sema3s) disrupt this process.

Pig (Porcine) Neuropilin 1 (NRP1) Interaktionspartner

  1. binding of Neuropilin-1 to VEGFR-2 (zeige KDR Proteine) requires the PDZ-binding domain of neuropilin-1

  2. Neuropilin-1 is essential for enhanced VEGF(165)-mediated vasodilatation in collateral-dependent coronary arterioles of exercise-trained pigs.

Neuropilin 1 (NRP1) Protein Überblick

Protein Überblick

This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors\; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Alternative names and synonyms associated with Neuropilin 1 (NRP1)

  • neuropilin 1 (NRP1)
  • neuropilin 1 (nrp1)
  • neuropilin 1 (Nrp1)
  • BDCA4 Protein
  • C530029I03 Protein
  • CD304 Protein
  • neuropilin Protein
  • NP-1 Protein
  • NP1 Protein
  • NPN-1 Protein
  • Npn1 Protein
  • Nrp Protein
  • nrp-1 Protein
  • NRP1 Protein
  • VEGF165R Protein

Bezeichner auf Proteinebene für Neuropilin 1 Proteine (NRP1)

neuropilin 1 , neuropilin-1 , A5 antigen , transmembrane receptor , vascular endothelial cell growth factor 165 receptor , A5 protein , Neuropilin-1 precursor (A5 protein) , A5-protein

450397 Pan troglodytes
539369 Bos taurus
100101701 Xenopus (Silurana) tropicalis
100171901 Pongo abelii
8829 Homo sapiens
18186 Mus musculus
246331 Rattus norvegicus
395560 Gallus gallus
477955 Canis lupus familiaris
397804 Xenopus laevis
100286859 Sus scrofa
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