anti-EGR1 (EGR1) Antikörper

anti-Early Growth Response 1 Antikörper (EGR1)
Auf finden Sie aktuell 132 Early Growth Response 1 (EGR1) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen EGR1 Kits (45) und EGR1 Proteine (19) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 204 EGR1 Produkte verfügbar.
A530045N19Rik, at225, egr, egr-1, EGR-1-A, EGR1, ETR103, g0s30, Krox-1, krox-24, krox24, Ngf1, NGF1-A, Ngfi, ngfi-a, NGFIA, tis8, wu:fj64b05, wu:fq25f01, Xegr-1, zenk, Zfp-6, zif-268, Zif268, znf225

Meistgesuchte Reaktivitäten zu anti-EGR1 (EGR1) Antikörper

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anti-Human EGR1 Antikörper:

anti-Mouse (Murine) EGR1 Antikörper:

anti-Rat (Rattus) EGR1 Antikörper:

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Am meisten referenzierte anti-EGR1 Antikörper

  1. Cow (Bovine) Polyclonal EGR1 Primary Antibody für IHC, WB - ABIN2779517 : Yu, de Belle, Liang, Adamson: Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses. in Molecular cell 2004 (PubMed)
    Zeige alle 8 Referenzen für 2779517

  2. Human Monoclonal EGR1 Primary Antibody für IF, WB - ABIN393945 : Kim, Jeong, Jeong, Kim, Lee, Shin, Kye, Son: Cigarette smoke-induced Egr-1 represses T beta R-II expression in human skin dermal fibroblasts. in Toxicology 2010 (PubMed)
    Zeige alle 5 Referenzen für 393945

  3. Human Monoclonal EGR1 Primary Antibody für WB - ABIN394244 : Xu, Toure, Qu, Lin, Song, Shen, Rosario, Garcia, Schmidt, Yan: Advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling and up-regulation of Egr-1 in hypoxic macrophages. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 5 Referenzen für 394244

  4. Human Monoclonal EGR1 Primary Antibody für ELISA, WB - ABIN969092 : Chan, Lee, Ho, Wong, Lam, Tang, Chan, Abdullah, Wong, Lam: High-level expression of early growth response-1 and association of polymorphism with total IgE and atopy in allergic rhinitis adults. in Clinica chimica acta; international journal of clinical chemistry 2009 (PubMed)
    Zeige alle 2 Referenzen für 969092

  5. Human Polyclonal EGR1 Primary Antibody für FACS, IF - ABIN389442 : Zhang, Chen, Wang, Guang, Han, Zhang, Tan, Gu: EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression. in Scientific reports 2014 (PubMed)
    Zeige alle 2 Referenzen für 389442

  6. Cow (Bovine) Polyclonal EGR1 Primary Antibody für IHC, WB - ABIN2779828 : Schnell, Zoller, Patel, Williams, Kersh: Early growth response gene 1 provides negative feedback to inhibit entry of progenitor cells into the thymus. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

  7. Cow (Bovine) Polyclonal EGR1 Primary Antibody für WB - ABIN2774222 : Akutagawa, Nishi, Kyo, Terauchi, Yamazawa, Higuma, Inoue, Isaka: Early growth response-1 mediates downregulation of telomerase in cervical cancer. in Cancer science 2008 (PubMed)

Weitere Antikörper gegen EGR1 Interaktionspartner

Pig (Porcine) Early Growth Response 1 (EGR1) Interaktionspartner

  1. Egr-1 silencing through intracoronary delivery of a targeting DNAzyme at the time of reperfusion following acute myocardial ischemia decreases myocardial inflammation and apoptosis leading to improved cardiac function.

  2. Intracoronary delivery of DNAzymes targeting human EGR-1 reduces infarct size following myocardial ischaemia reperfusion.

  3. Data suggest that Egr-1 protein levels may be tightly regulated in an attempt to diminish neurotoxicity or to enhance plasticity in newborn animals.

Human Early Growth Response 1 (EGR1) Interaktionspartner

  1. Finally, the authors show that EGFR (zeige EGFR Antikörper)-ERK1/2 (zeige MAPK1/3 Antikörper) and beta1-integrin signaling are the main pathways used for bacteria-mediated EGR1 upregulation.

  2. Early growth response (Egr)-1 is essential for fibrotic responses to Transforming growth factor (TGF)-beta (zeige TGFB1 Antikörper). Egr-1 mediates TGF-beta1 (zeige TGFB1 Antikörper)-induced COL1A1 (zeige COL1A1 Antikörper) and COL1A2 (zeige COL1A2 Antikörper) mRNA expression and acid-soluble collagen production in buccal mucosal fibroblasts (BMFs).The epigallocatechin-3-gallate (EGCG) can block TGF-beta1 (zeige TGFB1 Antikörper)-induced collagen production by attenuating Egr-1 expression in BMFs.

  3. Along with the reduction of ovarian cancer-2/disabled homolog 2 (DOC-2 (zeige DAB2 Antikörper)/DAB2) interactive protein (DAB2IP (zeige DAB2IP Antikörper)) expression, EGR-1 gene was upregulated in FI-treated cells. On the other hand, downregulation of EGR-1 gene expression sensitized radioresistant cells to IR accompanied by DAB2IP (zeige DAB2IP Antikörper) overexpression and STAT3 (zeige STAT3 Antikörper) inactivation. In addition, NF-kappaB (zeige NFKB1 Antikörper) inhibitor, BAY11-7082 enhanced resistant cells' radiosensitivity and chemos...

  4. ROS (zeige ROS1 Antikörper) activation of the MAPK (ERK (zeige MAPK1 Antikörper)-1 (zeige MAPK3 Antikörper)/2)/Egr-1 pathway is a main player in the regulatory mechanism for cigarette smoke extract-induced PlGF (zeige PGF Antikörper) production. Antioxidants could partly abolish these effects.

  5. adipose tissue-derived mesenchymal stem cells (AT-MSCs) from diabetic patients may contribute to microvascular damage and delay wound healing through the overexpression of EGR-1.

  6. KLF12 (zeige KLF12 Antikörper) promotes tumor growth by directly activating early growth response protein 1 (EGR1). The levels of KLF12 (zeige KLF12 Antikörper) and EGR1 correlate synergistically with a poor prognosis. These results indicate that KLF12 (zeige KLF12 Antikörper) likely plays an important role in CRC (zeige CALR Antikörper) and could serve as a potential prognostic marker and therapeutic target.

  7. Shikonin induces apoptosis in some lung cancer cells via activation of FOXO3a (zeige FOXO3 Antikörper)/EGR1/SIRT1 (zeige SIRT1 Antikörper) signaling, and AKT (zeige AKT1 Antikörper) and p300 (zeige EP300 Antikörper) negatively regulate this process via Bim (zeige BCL2L11 Antikörper) upregulation.

  8. Inhibition of mTORC1-mediated 4EBP1 (zeige EIF4EBP1 Antikörper) phosphorylation leads to decreased expression of c-MYC (zeige MYC Antikörper) and subsequent upregulation of the proapoptotic BCL2 (zeige BCL2 Antikörper) family member PUMA (zeige BBC3 Antikörper), whereas inhibition of mTORC2 (zeige CRTC2 Antikörper) results in nuclear factor-kappaB-mediated expression of the Early Growth Response 1 (EGR1) gene, which encodes a transcription factor that binds and transactivates the proapoptotic BCL2L11 (zeige BCL2L11 Antikörper) locus encoding BIM (zeige BCL2L11 Antikörper).

  9. Conversely, siRNA-mediated Klotho (zeige KL Antikörper) silencing up-regulated Egr-1, FN, and Col (zeige HDAC1 Antikörper) I expression and the p-Smad3/Smad3 (zeige SMAD3 Antikörper) ratio. Moreover, the effects of si-Klotho (zeige KL Antikörper) on Egr-1 expression were abolished by the TGF-beta1 (zeige TGFB1 Antikörper) inhibitor SB-431542. Klotho (zeige KL Antikörper) overexpression can prevent mesangial ECM (zeige MMRN1 Antikörper) production in high-glucose-treated human MCs (zeige SMCP Antikörper), an effect that has been partially attributed to Egr-1 down-regulation facilitated by TGF-beta1 (zeige TGFB1 Antikörper)/Smad3 (zeige SMAD3 Antikörper) s...

  10. ZHX1 (zeige ZHX1 Antikörper) was found to play essential roles in the proliferation, migration, and invasion of cholangiocarcinoma cells, and its effect on the proliferation was mediated partially through EGR1.

Cow (Bovine) Early Growth Response 1 (EGR1) Interaktionspartner

  1. Chronic hypoxia induces Egr-1 via activation of ERK1/2 (zeige MAPK1/3 Antikörper) and contributes to pulmonary vascular remodeling.

  2. The authors conclude that Egr-1 protein expression is very sensitive to upregulation by hypoxia in pulmonary artery adventitial fibroblasts and that it plays an important role in the autonomous growth phenotype induced by hypoxia in these cells.

  3. EGR-1's expression prior to ovulation and its stimulating effect on the expression of genes known to be involved in prostaglandin biosynthesis pathway, suggest its potential involvement in the regulation of preovulatory events in cattle.

Mouse (Murine) Early Growth Response 1 (EGR1) Interaktionspartner

  1. Herein, we report that silencing of Egr-1 in the hippocampus by shRNA reduces tau phosphorylation, lowers amyloid-beta (Abeta (zeige APP Antikörper)) pathology, and improves cognition in the 3xTg-Alzheimer disease mouse model.

  2. Egr-1 is a novel regulator of drebrin (zeige DBN1 Antikörper) expression, which is linked to changes in dendritic spine density

  3. In the present study, we have investigated the contribution of element C to Krox20 (zeige EGR2 Antikörper) expression, as it was the only characterized initiator element with an activity in r3. Using a conditional knock-out mutation of element C, we show that, unexpectedly, this element is not necessary for Krox20 (zeige EGR2 Antikörper) initial expression in r3.

  4. HAS2 (zeige HAS2 Antikörper)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1 (zeige MAPK3 Antikörper)/EGR1 signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (zeige TGFB1 Antikörper)-stimulated CD44V6/ERK (zeige EPHB2 Antikörper)/EGR1 signaling.

  5. Egr1 expression is sensitive to mechanical signals in tendon cells.

  6. age-related up-regulation of EGR1 promotes granulosa cell apoptosis in follicle atresia during ovarian aging.

  7. data indicate that Egr-1 promotes Abeta (zeige APP Antikörper) synthesis via transcriptional activation of BACE-1 (zeige BACE Antikörper) and suggest that Egr-1 plays role in activation of BACE-1 (zeige BACE Antikörper) and acceleration of Abeta (zeige APP Antikörper) synthesis in AD brain.

  8. EGR1, an early growth response factor, is a critical transcription factor that regulates the hepatic clock circuit.

  9. EGR1(-/-) mouse embryonic fibroblasts demonstrated lower susceptibility to Venezuelan equine encephalitis virus-induced cell death than isogenic wild-type fibroblasts, indicating that EGR1 modulates proapoptotic pathways following virus infection.

  10. The levels of B23 (zeige NPM1 Antikörper) expression are directly regulated by EGR1.

Zebrafish Early Growth Response 1 (EGR1) Interaktionspartner

  1. egr1 colocalizes with tyrosine hydroxylase (zeige TH Antikörper) in the olfactory bulb throughout brain development.

  2. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  3. The cDNA coding for zebrafish Egr1 was obtained and its expression pattern was examined during zebrafish embryogenesis using whole-mount in situ hybridization

  4. Egr1 gene has important role in zebrafish embryonic oculogenesis. Lens and retina with egr1 gene deletion were primitive and lacked differentiation. Such arrested retinal and lenticular development in Egr1 morphants resulted in microphthalmos.

Rabbit Early Growth Response 1 (EGR1) Interaktionspartner

  1. Gene therapy using in vivo transfection of an Egr-1 decoy ODN significantly inhibits proliferation of VSMC and intimal hyperplasia of vein grafts in a rabbit model.

  2. Results show that EGR1 plays a key role in tendon formation, healing, and repair through BMP12 (zeige GDF7 Antikörper)/Smad1 (zeige SMAD1 Antikörper)/5/8 pathway.

  3. Collectively, these results demonstrate that Egr-1 is expressed rapidly upon HSV-1 infection and that this novel induction could be due to the NFsmall ka, CyrillicB/CREB (zeige CREB1 Antikörper)-mediated transactivation.

EGR1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

Alternative names and synonyms associated with EGR1

  • early growth response protein 1(Egr-1, NGFI-A) (EGR-1) Antikörper
  • early growth response protein 1 (egr-1) (CNK00890) Antikörper
  • early growth response 1 (EGR1) Antikörper
  • early growth response 1 (Egr1) Antikörper
  • early growth response 1 (egr1) Antikörper
  • early growth response 1 (egr1-a) Antikörper
  • early growth response protein 1 (EGR-1) Antikörper
  • A530045N19Rik Antikörper
  • at225 Antikörper
  • egr Antikörper
  • egr-1 Antikörper
  • EGR-1-A Antikörper
  • EGR1 Antikörper
  • ETR103 Antikörper
  • g0s30 Antikörper
  • Krox-1 Antikörper
  • krox-24 Antikörper
  • krox24 Antikörper
  • Ngf1 Antikörper
  • NGF1-A Antikörper
  • Ngfi Antikörper
  • ngfi-a Antikörper
  • NGFIA Antikörper
  • tis8 Antikörper
  • wu:fj64b05 Antikörper
  • wu:fq25f01 Antikörper
  • Xegr-1 Antikörper
  • zenk Antikörper
  • Zfp-6 Antikörper
  • zif-268 Antikörper
  • Zif268 Antikörper
  • znf225 Antikörper

Bezeichner auf Proteinebene für EGR1

early growth response protein 1(Egr-1, NGFI-A) , early growth response protein 1 (egr-1) , early growth response 1 , EGR-1 , early growth response protein 1 , nerve growth factor-induced protein A , transcription factor ETR103 , transcription factor Zif268 , zinc finger protein 225 , zinc finger protein Krox-24 , Krox-24 nuclear protein , zinc finger protein ZENK , etID309970.14 , zinc-finger transcriptional protein , early growth response protein 1-A

397332 Sus scrofa
3254484 Cryptococcus neoformans var. neoformans JEC21
100618969 Monodelphis domestica
1958 Homo sapiens
481528 Canis lupus familiaris
407125 Bos taurus
13653 Mus musculus
24330 Rattus norvegicus
462097 Pan troglodytes
100716298 Cavia porcellus
100520726 Sus scrofa
373931 Gallus gallus
443547 Ovis aries
30498 Danio rerio
100008579 Taeniopygia guttata
399162 Xenopus laevis
100009491 Oryctolagus cuniculus
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