TMSB4X Proteine (TMSB4X)

Bezeichnung:
Thymosin beta-4 Proteine (TMSB4X)
Auf www.antikoerper-online.de finden Sie aktuell 34 Thymosin beta-4 (TMSB4X) Proteine von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TMSB4X Antikörper (77) und TMSB4X Kits (41) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 165 TMSB4X Produkte verfügbar.
Synonyme:
FX, Ptmb4, Tb4, TB4X, tmsb4, TMSB4X
alle Proteine anzeigen Gen GeneID UniProt
TMSB4X 7114 P62328
TMSB4X 19241 P20065
TMSB4X 81814 P62329

Weitere Synonyme anzeigen

TMSB4X Proteine (TMSB4X) nach Spezies

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Weitere Proteine zu TMSB4X Interaktionspartnern

Human Thymosin beta-4 (TMSB4X) Interaktionspartner

  1. Tbeta4 exerts a protective effect on murine colitis, indicating that recombinant adeno-associated virus carrying thymosin beta4 could potentially be developed into a promising agent for the therapy of inflammatory bowel diseases.

  2. Results showed that the TMSB4 pseudogene, lncRNA-MSR (zeige MTRR Proteine), was upregulated in the damaged cartilage and was activated in chondrocytes in response to mechanical stress. Furthermore, lncRNA-MSR (zeige MTRR Proteine) regulated the expression of TMSB4 by competing with miRNA-152 in chondrocytes.

  3. Tbeta4 gene silencing in A549 and H1299 cells inhibited cell proliferation, migration, and invasion in vitro and decreased tumor growth in vivo. Mechanistic investigations revealed a significant decrease in Notch1 (zeige NOTCH1 Proteine) activation in Tbeta4 gene-silenced cells.

  4. Developed an innovative biotechnological method for thymosin beta4 production that employs the peptide acetylation in vivo.

  5. Serum thymosin beta4 concentrations were correlated with the occurrence and severity of obstructive sleep apnea syndrome.

  6. this study demonstrated, for the first time, that Tbeta4 was down-regulated in ROS (zeige ROS1 Proteine)-stimulated PDLCs as well as Tbeta4 activation exhibited anti-inflammatory effects and anti-osteoclastogenesis in vitro.

  7. This article reviews the potential role of thymosin beta 4 in liver fibrosis by describing the effects of exogenous and endogenous thymosin beta 4 , and discusses the possible signaling pathway regulated by TB4X. [review]

  8. The results of the present study suggested that Tb4 may promote HB metastasis via the induction of EMT (zeige ITK Proteine), and that Tb4 may therefore be a target for the development of novel treatments for patients with Hepatoblastoma .

  9. these results suggest that NO could regulate the expression of Tbeta4 by direct or indirect effect of HIF-1alpha (zeige HIF1A Proteine) on Tbeta4 promoter.

  10. the exchange of bound actin between Tbeta4 and profilin (zeige PFN1 Proteine) involves both steric and allosteric components.

Cow (Bovine) Thymosin beta-4 (TMSB4X) Interaktionspartner

  1. TMSB4 and/or TMSB10 (zeige TMSB10 Proteine) ovarian expression patterns suggest that these two thymosins may be involved in cumulus modifications during maturation.

Horse (Equine) Thymosin beta-4 (TMSB4X) Interaktionspartner

Mouse (Murine) Thymosin beta-4 (TMSB4X) Interaktionspartner

  1. Our data suggest that Tbeta4 is required for setting correct sarcomere length and for appropriate splicing of titin (zeige TTN Proteine), not only in the heart but also in skeletal muscle.

  2. Increased Tb4 expression was observed in ethanol treated microglia. Knockdown of Tb4 enhanced ethanol-induced inflammatory mediators tumor necrosis factor-alpha and interleukin-1beta and nitric oxide in BV-2 cells was performed.

  3. Results provide evidence that Tbeta4 regulate the levels of VEGF (zeige VEGFA Proteine) and MMP-2 (zeige MMP2 Proteine) via the Wnt (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine)/Lef-1 (zeige LEF1 Proteine) signaling pathway to influence the growth of blood vessels around hair follicles and to activate cell migration.

  4. this study demonstrated, for the first time, that Tbeta4 was down-regulated in ROS (zeige ROS1 Proteine)-stimulated PDLCs as well as Tbeta4 activation exhibited anti-inflammatory effects and anti-osteoclastogenesis in vitro.

  5. Tbeta4 appears to regulate P38/ERK (zeige MAPK1 Proteine)/AKT (zeige AKT1 Proteine) signaling via its effect on VEGF (zeige VEGFA Proteine) expression, with a resultant effect on the speed of hair growth, the pattern of HFs and the number of hair shafts

  6. This study provides putative information concerning the signaling pathway through which Tb4 induces RUNX2 (zeige RUNX2 Proteine) expression, which may help to understand the regulation of tooth development and tooth regeneration.

  7. Tbeta4 substantially inhibited bleomycin-induced IL-17 (zeige IL17A Proteine) over-expression in the lung tissue: a decreased amount of IL17 (zeige IL17A Proteine)-producing cells and inhibited IL-17 (zeige IL17A Proteine) expression in lung with Tbeta4 treatment correlate with its anti-inflammatory and anti-fibrotic effects.

  8. These data suggest that Tbeta4 suppresses the TLR proinflammatory pathway by up-regulating miR (zeige MLXIP Proteine)-146a.

  9. Thymosin beta4 may play a role in aging-related hearing loss.

  10. These data show that thymosinbeta4 and beta-actin are over-expressed during nurse cell formation upon T. spiralis infection and may be involved in nurse cell formation along with other actin-binding proteins.

TMSB4X Protein Überblick

Protein Überblick

This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y.

Alternative names and synonyms associated with TMSB4X

  • thymosin beta 4, X-linked (TMSB4X)
  • thymosin, beta 4, X chromosome (Tmsb4x)
  • thymosin beta 4 peptide (tmsb4x)
  • thymosin beta 4, X-linked (TMSB4)
  • thymosin beta 4, X-linked (Tmsb4x)
  • thymosin, beta 4-like (LOC100339394)
  • thymosin beta 4 (LOC100860922)
  • FX Protein
  • Ptmb4 Protein
  • Tb4 Protein
  • TB4X Protein
  • tmsb4 Protein
  • TMSB4X Protein

Bezeichner auf Proteinebene für Thymosin beta-4 Proteine (TMSB4X)

prothymosin beta-4 , t beta-4 , thymosin beta-4 , thymosin, beta 4, X chromosome , prothymosin beta 4 , t beta 4 , thymosin beta 4, X-linked , thymosin beta 4Xen , thymosin beta 4, X chromosome , thymosin, beta 4, X-linked , thymosin, beta 4 , seraspenide , thymosin beta 4 X-linked , thymosin b4

GENE ID SPEZIES
7114 Homo sapiens
19241 Mus musculus
81814 Rattus norvegicus
399438 Xenopus laevis
733606 Sus scrofa
100173314 Pongo abelii
282386 Bos taurus
408047 Gallus gallus
781334 Bos taurus
100034015 Equus caballus
100216317 Sus scrofa
100736168 Cavia porcellus
100339394 Oryctolagus cuniculus
100860922 Capra hircus
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