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High RACGAP1 (zeige RACGAP1 ELISA Kits) expression is associated with Basal-like Breast Cancers.
Data suggest that MGCRABGAP is involved in mammalian spermiogenesis by modulating RAB10 (zeige RAB10 ELISA Kits).
This study showed that the overexpressions of Ki67 (zeige MKI67 ELISA Kits), RacGAP1 (zeige RACGAP1 ELISA Kits), and TOP2a (zeige TOP2A ELISA Kits) affect the prognosis of female breast cancer patients adversely
Data confirmed a strong correlation of AURKA (zeige AURKA ELISA Kits) and Wnt (zeige WNT2 ELISA Kits)-modulator RACGAP1 (zeige RACGAP1 ELISA Kits) gene expression both in the gastric tumor, the tumor-adjacent and the tumor-distant mucosa.
RacGAP1 (zeige RACGAP1 ELISA Kits) Is a Novel Downstream Effector of E2F7 (zeige E2F7 ELISA Kits)-Dependent Resistance to Doxorubicin and Is Prognostic for Overall Survival in Squamous Cell Carcinoma
RACGAP1 (zeige RACGAP1 ELISA Kits) expression levels in the nucleus and cytoplasm, determined by immunohistochemical staining, predict opposite clinical outcomes and that both could be independent prognostic markers for colorectal cancer.
central spindle assembly and 2 Plk1 (zeige PLK1 ELISA Kits)-dependent phosphorylations are required to establish efficient binding of the Ect2 (zeige ECT2 ELISA Kits) BRCT in early cytokinesis.
RacGAP1 (zeige RACGAP1 ELISA Kits) expression at the invasive front in gastric cancer was significantly correlated with factors reflecting tumor progression and poor prognosis.RACGAP1 gene expression in diffuse type gastric cancer was elevated.
RacGAP1 mediated endothelial barrier function loss and melanoma transmigration in a focal adhesion-dependent manner.RacGAP1 activation mediates focal adhesion assembly and actin stress fiber formation.
High RacGAP1 (zeige RACGAP1 ELISA Kits) expression was an independent predictive marker for lymph node metastasis, recurrence and poor prognosis in colorectal cancer patients.
results indicate that, mTOR (zeige FRAP1 ELISA Kits), Bad, or Survivin (zeige BIRC5 ELISA Kits) are not required for p120 RasGAP fragment N to protect cells from cell death; conclude that downstream targets of Akt (zeige AKT1 ELISA Kits) other than mTORC1, Bad, or survivin (zeige BIRC5 ELISA Kits) mediate fragment N-induced protection or that several Akt (zeige AKT1 ELISA Kits) effectors can compensate for each other to induce the pro-survival fragment N-dependent responses
RASA1 (zeige RASA1 ELISA Kits) catalytic activity is essential for the function and development of lymphatic vessel valves.
These results indicate that the caspase-3 (zeige CASP3 ELISA Kits)/p120 RasGAP stress-sensing module impacts on carcinogen-induced liver cancer incidence but not sufficiently so as to affect overall survival.
Double-deficient RASA1 (zeige RASA1 ELISA Kits)-neurofibromin 1 (zeige NF1 ELISA Kits) mice developed T cell acute lymphoblastic leukemia/lymphoma, which originated at an early point in T cell development and was dependent on activating mutations in the Notch1 (zeige NOTCH1 ELISA Kits) gene.
Rasa1 (zeige RASA1 ELISA Kits) may have a role in pathogenesis of capillary malformation-arteriovenous malformation in a mouse model
Regulation of Rasa1 (zeige RASA1 ELISA Kits) translation by miR (zeige MLXIP ELISA Kits)-132 was seen in severed axons, demonstrating local function within the axon.
RASA1 (zeige RASA1 ELISA Kits) mutation is responsible for the aberrant lymphatic architecture and functional abnormalities, as visualized in the PKWS (zeige RASA1 ELISA Kits) subject and in the animal model.
MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA by repressing RAS p21 GTPase activating protein (zeige RASA1 ELISA Kits) 1 (RASA1 (zeige RASA1 ELISA Kits))
14-3-3 (zeige YWHAQ ELISA Kits) negatively regulates the RGC downstream of the PI3-kinase (zeige PIK3CA ELISA Kits)/Akt (zeige AKT1 ELISA Kits) signaling pathway
Caspase-3 (zeige CASP3 ELISA Kits) is a stress intensity sensor that controls cell fate by either initiating a RasGAP (zeige RASA1 ELISA Kits) cleavage-dependent cell resistance program or a cell suicide response mediated by akt (zeige AKT1 ELISA Kits).
The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis, controlling cell growth and differentiation of hematopoietic cells, regulating spermatogenesis, and in neuronal proliferation. Alternatively spliced transcript variants have been found for this gene.
GTPase activating protein
, male germ cell RacGap
, protein CYK4 homolg
, protein CYK4 homolog
, rac GTPase-activating protein 1
, GTPase-activating protein
, RAS p21 protein activator 1
, ras GTPase-activating protein 1