CD31 Proteine (PECAM1)

Auf finden Sie aktuell 38 Platelet/endothelial Cell Adhesion Molecule (PECAM1) Proteine von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CD31 Antikörper (1307) und CD31 Kits (84) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 1449 CD31 Produkte verfügbar.
C85791, Cd31, CD31/EndoCAM, endoCAM, GPIIA', PECA1, Pecam, PECAM-1
alle Proteine anzeigen Gen GeneID UniProt
PECAM1 5175 P16284
PECAM1 18613 Q08481
PECAM1 29583 Q3SWT0

CD31 Proteine (PECAM1) nach Spezies

Weitere Proteine zu CD31 Interaktionspartnern

Cow (Bovine) Platelet/endothelial Cell Adhesion Molecule (PECAM1) Interaktionspartner

  1. novel pathway for PECAM-1 regulation

  2. PECAM-1 may not function as a major mechanoreceptor for activation of MAPK (zeige MAPK1 Proteine) and AKT (zeige AKT1 Proteine) in ECs and that there are likely to be other mechanoreceptors in ECs functioning to detect shear stress and trigger intercellular signals.

  3. PECAM-1 and Fyn (zeige FYN Proteine) are essential components of a PECAM-1-based mechanosensory complex in endothelial cells

  4. PECAM-1 plays a role in the early pathogenesis of thrombotic meningoencephalitis.

Human Platelet/endothelial Cell Adhesion Molecule (PECAM1) Interaktionspartner

  1. Dimer conformation of soluble PECAM-1

  2. RrgA, binds both polymeric immunoglobulin receptor (pIgR (zeige PIGR Proteine)) and PECAM-1, whereas the choline binding protein PspC binds, but to a lower extent, only pIgR (zeige PIGR Proteine)

  3. this study shows a significant role for CD31 (zeige HBA1 Proteine) during T cell development

  4. Cells in high glucose for 7 days showed a significant decrease in mRNA expression of CD31 (zeige HBA1 Proteine) and VE-cadherin (zeige CDH5 Proteine), and a significant increase in that of alpha-SMA (zeige SMN1 Proteine) and collagen I.

  5. Patients who had optic neuritis that progressed to multiple sclerosis had a decrease in serum PECAM-1 levels.

  6. Platelet endothelial cell adhesion molecule (PECAM-1) is expressed in endothelial cells (ECs), platelets, and leukocytes, regulating the interaction between those cells.

  7. Data indicate no association of maternal or fetal ITGA2 (zeige ITGA2 Proteine) C807T SNP, ITGB3 (zeige ITGB3 Proteine) T1565C SNP, PECAM1 CTG - GTG (zeige GGT1 Proteine) and SELP (zeige SEPP1 Proteine) A/C polymorphisms with fetal growth restriction (FGR (zeige FGR Proteine)).

  8. these data suggest that a sialic acid-containing glycan emanating from Asn-25 reinforces dynamic endothelial cell-cell interactions by stabilizing the PECAM-1 homophilic binding interface.

  9. Decreased FoxP3 (zeige FOXP3 Proteine) expression in CD31 (zeige HBA1 Proteine)(+) Tr cells.

  10. These results suggested that PECAM-1 could mediate platelet adhesion to endothelial cells under shear stress. Platelets binding to endothelial cells interfered with endothelial cell mechanotransduction through PECAM-1, affecting endothelial cell inflammatory responses towards pathological shear flow.

Mouse (Murine) Platelet/endothelial Cell Adhesion Molecule (PECAM1) Interaktionspartner

  1. RrgA, binds both polymeric immunoglobulin receptor (pIgR (zeige PIGR Proteine)) and PECAM-1, whereas the choline binding protein PspC binds, but to a lower extent, only pIgR (zeige PIGR Proteine)

  2. Both the number of lung CD31-CD45 (zeige PTPRC Proteine)-Sca-1+ cells and the expression levels of the Shh (zeige SHH Proteine) signaling pathway were downregulated in the lung tissues of mice with pulmonary emphysema. These cells and Shh (zeige SHH Proteine) signaling pathway are reactivated during acute adenovirus infection.

  3. In FVB/n mice, PECAM functions upstream of CD99 (zeige CD99 Proteine) in leukocyte diapedesis and blocking antibodies against either molecule arrest neutrophils before they traverse the endothelium. However, in C57BL/6 mice, PECAM and CD99 (zeige CD99 Proteine) appear to function at a different step, as the same antibodies arrest leukocyte migration through the endothelial basement membrane.

  4. These studies indicate a role for PECAM-1 in enhancing the inhibitory functions of TGF-beta (zeige TGFB1 Proteine) in T cells

  5. PECAM1 acts upstream of Gab1, promoting Gab1/Akt (zeige AKT1 Proteine)/eNOS (zeige NOS3 Proteine) phosphorylation and activation, thereby confers EC responsiveness to flow.

  6. Radiation-induced stress conditions induce a transient accumulation of granulocytes within the liver by down-regulation/absence of PECAM-1.

  7. CD31 gene transfer is sufficient to recapitulate the cytoprotective mechanisms in CD31(-) pancreatic beta cells, which become resistant to immune-mediated rejection when grafted in fully allogeneic recipients

  8. PECAM1+ melanoma cells form vascular channels

  9. Data indicate that in lymphocyte specific 1 (zeige LSP1 Proteine) protein (LSP1 (zeige LSP1 Proteine))-deficient mice, PECAM-1 expression was reduced in endothelial cells, but not in neutrophils.

  10. Nck (zeige NCK1 Proteine) promoted oxidative stress-induced (zeige SQSTM1 Proteine) activation of NF-kappaB (zeige NFKB1 Proteine) by coupling the tyrosine phosphorylation of PECAM-1 (platelet endothelial cell adhesion molecule-1) to the activation of p21-activated kinase

CD31 (PECAM1) Protein Überblick

Protein Überblick

The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.

Alternative names and synonyms associated with CD31 (PECAM1)

  • platelet/endothelial cell adhesion molecule (LOC569386)
  • platelet/endothelial cell adhesion molecule (PECAM1)
  • platelet/endothelial cell adhesion molecule 1 (PECAM1)
  • platelet/endothelial cell adhesion molecule 1 (Pecam1)
  • C85791 Protein
  • Cd31 Protein
  • CD31/EndoCAM Protein
  • endoCAM Protein
  • GPIIA' Protein
  • PECA1 Protein
  • Pecam Protein
  • PECAM-1 Protein

Bezeichner auf Proteinebene für PECAM1

platelet endothelial cell adhesion molecule , CD31 antigen , PECAM-1 , platelet/endothelial cell adhesion molecule (CD31 antigen) , PECAM-1/CD31 , type I transmembrane endothelial adhesion molecule

569386 Danio rerio
282303 Bos taurus
5175 Homo sapiens
18613 Mus musculus
29583 Rattus norvegicus
396941 Sus scrofa
100734230 Cavia porcellus
610775 Canis lupus familiaris
771243 Gallus gallus
100303608 Ovis aries
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