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CD31 Proteine (PECAM1)

Bezeichnung:
Platelet/endothelial Cell Adhesion Molecule Proteine (PECAM1)
Auf www.antikoerper-online.de finden Sie aktuell 37 Platelet/endothelial Cell Adhesion Molecule (PECAM1) Proteine von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CD31 Antikörper (1250) und CD31 Kits (80) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 1387 CD31 Produkte verfügbar.
Synonyme:
C85791, Cd31, CD31/EndoCAM, endoCAM, GPIIA', PECA1, Pecam, PECAM-1
alle Proteine anzeigen Gen GeneID UniProt
PECAM1 5175 P16284
PECAM1 18613 Q08481
PECAM1 29583 Q3SWT0

Weitere Synonyme anzeigen

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Am meisten referenzierte CD31 Proteine

  1. Human CD31 Protein expressed in Human Cells - ABIN2002172 : Newman, Berndt, Gorski, White, Lyman, Paddock, Muller: PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. in Science (New York, N.Y.) 1990 (PubMed)
    Zeige alle 5 Referenzen für ABIN2002172

  2. Human CD31 Protein expressed in Human Cells - ABIN2002174 : Sun, Williams, Yan, Amin, Albelda, DeLisser et al.: Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface ... in The Journal of biological chemistry 1996 (PubMed)
    Zeige alle 5 Referenzen für ABIN2002174

  3. Mouse (Murine) CD31 Protein expressed in Human Cells - ABIN2007760 : Newton-Nash, Newman: A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Zeige alle 5 Referenzen für ABIN2007760

Weitere Proteine zu CD31 Interaktionspartnern

Cow (Bovine) Platelet/endothelial Cell Adhesion Molecule (PECAM1) Interaktionspartner

  1. novel pathway for PECAM-1 regulation

  2. PECAM-1 may not function as a major mechanoreceptor for activation of MAPK (zeige MAPK1 Proteine) and AKT (zeige AKT1 Proteine) in ECs and that there are likely to be other mechanoreceptors in ECs functioning to detect shear stress and trigger intercellular signals.

  3. PECAM-1 and Fyn (zeige FYN Proteine) are essential components of a PECAM-1-based mechanosensory complex in endothelial cells

  4. PECAM-1 plays a role in the early pathogenesis of thrombotic meningoencephalitis.

Human Platelet/endothelial Cell Adhesion Molecule (PECAM1) Interaktionspartner

  1. Platelet endothelial cell adhesion molecule (PECAM-1) is expressed in endothelial cells (ECs), platelets, and leukocytes, regulating the interaction between those cells.

  2. Data indicate no association of maternal or fetal ITGA2 (zeige ITGA2 Proteine) C807T SNP, ITGB3 (zeige ITGB3 Proteine) T1565C SNP, PECAM1 CTG - GTG (zeige GGT1 Proteine) and SELP (zeige SEPP1 Proteine) A/C polymorphisms with fetal growth restriction (FGR (zeige FGR Proteine)).

  3. these data suggest that a sialic acid-containing glycan emanating from Asn-25 reinforces dynamic endothelial cell-cell interactions by stabilizing the PECAM-1 homophilic binding interface.

  4. Decreased FoxP3 (zeige FOXP3 Proteine) expression in CD31 (zeige HBA1 Proteine)(+) Tr cells.

  5. These results suggested that PECAM-1 could mediate platelet adhesion to endothelial cells under shear stress. Platelets binding to endothelial cells interfered with endothelial cell mechanotransduction through PECAM-1, affecting endothelial cell inflammatory responses towards pathological shear flow.

  6. Immunohistochemical expression of CD31 and vascular endothelial growth factor (VEGF) were assessed in parallel.

  7. CD31 (zeige HBA1 Proteine) is expressed in mycosis fungoides (MF) skin biopsies, which provides new evidence for the role of angiogenesis in the progression of MF

  8. The Leu125Val polymorphism of PECAM-1 and the level of soluble PECAM-1 are not associated with diabetic nephropathy in Caucasians with type 2 diabetes mellitus.

  9. We provide the first report that pro-angiogenic genes PECAM1, PTGS1 (zeige PTGS1 Proteine), FGD5 (zeige FGD5 Proteine), and MCAM (zeige MCAM Proteine) may play a vital role in pathological dermal angiogenesis disorders of psoriasis.

  10. The PECAM-1 functions as an adhesive stress-response protein to both maintain endothelial cell junctional integrity and speed restoration of the vascular permeability barrier following inflammatory or thrombotic challenge.

Mouse (Murine) Platelet/endothelial Cell Adhesion Molecule (PECAM1) Interaktionspartner

  1. These studies indicate a role for PECAM-1 in enhancing the inhibitory functions of TGF-beta (zeige TGFB1 Proteine) in T cells

  2. PECAM1 acts upstream of Gab1, promoting Gab1/Akt (zeige AKT1 Proteine)/eNOS (zeige NOS3 Proteine) phosphorylation and activation, thereby confers EC responsiveness to flow.

  3. Radiation-induced stress conditions induce a transient accumulation of granulocytes within the liver by down-regulation/absence of PECAM-1.

  4. CD31 gene transfer is sufficient to recapitulate the cytoprotective mechanisms in CD31(-) pancreatic beta cells, which become resistant to immune-mediated rejection when grafted in fully allogeneic recipients

  5. PECAM1+ melanoma cells form vascular channels

  6. Data indicate that in lymphocyte specific 1 (zeige LSP1 Proteine) protein (LSP1 (zeige LSP1 Proteine))-deficient mice, PECAM-1 expression was reduced in endothelial cells, but not in neutrophils.

  7. Nck (zeige NCK1 Proteine) promoted oxidative stress-induced (zeige SQSTM1 Proteine) activation of NF-kappaB (zeige NFKB1 Proteine) by coupling the tyrosine phosphorylation of PECAM-1 (platelet endothelial cell adhesion molecule-1) to the activation of p21-activated kinase

  8. PECAM-1 has a role in mediating the profibrotic and prometastasic environment caused by ethanol in endothelial cells

  9. the T cell co-inhibitory receptor CD31 prevents the formation of functional T/B immunological synapses and that therapeutic strategies aimed at sustaining CD31 signaling will attenuate the development of autoimmune responses in vivo.

  10. MMP-9 (zeige MMP9 Proteine) activity disrupts vascular integrity at least partially through a PECAM-1 dependent mechanism and interferes with regeneration of steatotic livers after ischemia/reperfusion injury.

CD31 (PECAM1) Protein Überblick

Protein Überblick

The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.

Alternative names and synonyms associated with CD31 (PECAM1)

  • platelet/endothelial cell adhesion molecule (LOC569386)
  • platelet/endothelial cell adhesion molecule (PECAM1)
  • platelet/endothelial cell adhesion molecule 1 (PECAM1)
  • platelet/endothelial cell adhesion molecule 1 (Pecam1)
  • C85791 Protein
  • Cd31 Protein
  • CD31/EndoCAM Protein
  • endoCAM Protein
  • GPIIA' Protein
  • PECA1 Protein
  • Pecam Protein
  • PECAM-1 Protein

Bezeichner auf Proteinebene für PECAM1

platelet endothelial cell adhesion molecule , CD31 antigen , PECAM-1 , platelet/endothelial cell adhesion molecule (CD31 antigen) , PECAM-1/CD31 , type I transmembrane endothelial adhesion molecule

GENE ID SPEZIES
569386 Danio rerio
282303 Bos taurus
5175 Homo sapiens
18613 Mus musculus
29583 Rattus norvegicus
396941 Sus scrofa
100734230 Cavia porcellus
610775 Canis lupus familiaris
771243 Gallus gallus
100303608 Ovis aries
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