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anti-Human Urocortin Antikörper:
anti-Rat (Rattus) Urocortin Antikörper:
anti-Mouse (Murine) Urocortin Antikörper:
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These results suggest that a regulatory system exists in the bovine thyroid gland based on UCN, CRHR1 (zeige CRHR1 Antikörper) and CRHR2 (zeige CRHR2 Antikörper) and that UCN plays a role in the regulation of thyroid physiological functions through an autocrine/paracrine mechanism.
Results describe the distribution of urotensin I, UIIalpha and UIIbeta mRNAs in different organs and the cellular localization of the three mRNAs in the spinal cord by in situ hybridization (ISH (zeige ANTXR2 Antikörper)) histochemistry.
UCN I is secreted from human glioblastoma cells by exocytosis through constitutive secretory granules.
Findings identify Ucn as a potential mediator that inhibits TGFbeta1 (zeige TGFB1 Antikörper) oncogenic signaling in breast neoplasm.
In women with adnexal endometrioma versus teratoma (zeige DND1 Antikörper), the medians were 105.31 pg/mL versus 120.84 pg/mL for urocortin, 7.16 pg/mL versus 9.13 pg/mL for leptin (zeige LEP Antikörper) and 584.33 pg/mL versus 657.82 pg/mL for ghrelin (zeige GHRL Antikörper) (p > 0.05), respectively.
Ucn1 prevents the development of atherosclerosis by suppressing EC inflammatory response and proliferation, macrophage foam cell formation, and VSMC migration and proliferation
These data suggest that UVB-stimulated Ucn1 contributes to TRP1 (zeige PRSS1 Antikörper) production via the transcription of both Nurr-1 (zeige NR4A2 Antikörper) and Nur77 (zeige NR4A1 Antikörper). Ucn1, produced in melanoma cells, acts on melanoma cells themselves in an autocrine manner.
Production of CRF (zeige CRH Antikörper) and UCN1 in human dendritic cells is strongly augmented by commensal intestinal bacteria.
Cardioplegic arrest failed to induce cardiac myocyte overexpression of urocortin in diabetic hearts.
Urocortin expression inversely correlates with higher tumor grade and advanced tumor stage in gastric adenocarcinomas.
all neonates expressed UCN1 in the Edinger-Westphal nucleus independent of the degree of neuropathological injury.
Ucn is both an essential chondrocyte survival signal peptide and a chondroprotective agent in the presence of pro-apoptotic stimuli.
it is shown that CRH (zeige CRH Antikörper) and UCN upregulate galectin-1 (zeige LGALS1 Antikörper) expression in Ishikawa cell line and macrophages and this effect is mediated through CRHR1 (zeige CRHR1 Antikörper).
This study aims to investigate the cellular localization of CRF (zeige CRH Antikörper) and UCNs in the ileum and to explore whether and how this cellular expression is altered in conditions of intestinal Schistosoma mansoni-induced inflammation.
CNTF (zeige CNTF Antikörper) activates hypothalamic urocortin 1-expressing neurons both in vitro and in vivo.
The absence of the CB1 (zeige CNR1 Antikörper) receptor alters the Ucn1 mRNA and peptide levels in Edinger-Westphal nucleus neurones, concomitant with an augmented stress response and increased anxiety-like behaviour.
EWcp-Ucn1 neurons play an important role in EtOH intake, preference, and reward.
CRF(1) agonists, Ucn 1 and stressin(1) -A, reduced feeding and induced interoceptive stress, whereas Ucn 2 potently suppressed feeding via a CRF(2) -dependent mechanism without eliciting malaise
Data suggest that UCN regulates osteoclast resorption by suppressing osteoclast maturation/function via suppression of constitutively active cation channel (zeige TRPV1 Antikörper) (CRFR2beta (zeige CRHR2 Antikörper)) with properties of canonical transient receptor potential 1 (TRPC1 (zeige TRPC1 Antikörper)) channel.
Ucn1 gene was downregulated in 5-HTT (zeige SLC6A4 Antikörper) KO and upregulated in 5-HTT (zeige SLC6A4 Antikörper) TG mice which exhibit opposite changes in anxiety-related behavior; findings suggesti this peptide can be involved in behavioral changes observed in 5-HTT (zeige SLC6A4 Antikörper) mutant mice
This study provides provide evidence for leptin (zeige LEP Antikörper) actions that go beyond the hypothalamus and proposes that leptin (zeige LEP Antikörper) can directly influence the activity of the midbrain Ucn1 neurons.
The lack of brain Ucn 1 immunoreactivity at birth and the gradual postnatal increase in Ucn 1 in the perioculomotor area suggests that this peptide plays a greater behavioral role in adulthood than during the early postnatal development of an organism.
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.
, urocortin, preproprotein