Apelin Proteine (APLN)

Apelin Proteine (APLN)
Auf www.antikoerper-online.de finden Sie aktuell 10 Apelin (APLN) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Apelin Antikörper (94) und Apelin Kits (43) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 158 Apelin Produkte verfügbar.
6030430G11Rik, APEL, APLN, preproapelin, Xapelin, XNPEP2
alle Proteine anzeigen Gen GeneID UniProt
APLN 30878 Q9R0R4
APLN 8862 Q9ULZ1
APLN 58812 Q9R0R3

Weitere Synonyme anzeigen

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Weitere Proteine zu Apelin Interaktionspartnern

Zebrafish Apelin (APLN) Interaktionspartner

  1. Apelin signaling regulates lymphatic development by promoting serine-threonine kinase Akt/protein kinase B (zeige AKT1 Proteine) activity in a VEGF-C (zeige VEGFC Proteine)/VEGF receptor (zeige FLT1 Proteine) 3-independent manner during zebrafish embryogenesis.

  2. Apelin knockdown inhibits both hypoxia-induced endothelial cell proliferation in vitro and hypoxia-induced vessel regeneration in the caudal fin regeneration of zebrafish.

Mouse (Murine) Apelin (APLN) Interaktionspartner

  1. Results revealed that apelin-13 attenuated brain edema and reduced cellular death by suppressing apoptosis after intracerebral hemorrhage in mice.

  2. Apelin-36-[L28C(30kDa (zeige TAF10 Proteine)-PEG (zeige PAEP Proteine))] provides a starting point for the development of diabetes therapeutics that are devoid of the blood pressure effects associated with canonical APJ (zeige APLNR Proteine) activation

  3. miR (zeige MLXIP Proteine)-503 promotes cardiac fibrosis via miR (zeige MLXIP Proteine)-503-Apelin-13-TGF-beta (zeige TGFB1 Proteine)-CTGF (zeige CTGF Proteine)-collagen production pathway.

  4. Apelin directly interferes with thrombin-mediated signaling pathways and platelet activation, secretion, and aggregation, but not with ADP and thromboxane A2-mediated pathways.

  5. Apelin regulates inflammatory response, diminishes inflammatory remote organ damage and improves survival in an experimental model of burn sepsis, which is at least partly mediated by a phosphatidylinositol 3-kinase/protein kinase B (zeige AKT1 Proteine) dependent pathway.

  6. apelin is a potential activator of inflammation factors through the PI3K/Akt (zeige AKT1 Proteine) and Erk (zeige EPHB2 Proteine) signaling pathway and is potential therapeutically relevant to inflammatory responses of microglia cells

  7. we showed the effect of Apelin on RAW264.7 macrophage under normal and hypoxic condition, which could further influence the angiogenesis and inflammation process that promoted by macrophages.

  8. PDL- and Cer-induced CP resulted in increased production of the pancreatic BMP2, apelin, and PTHrP signaling systems and that significant cross talk occurred among pancreatic BMP2, apelin, and PTHrP

  9. Therapeutic potential of apelin to prevent myocardial metabolic abnormalities in heart failure paired with obesity.

  10. Data suggest that CTRP3 (cartducin) up-regulates expression and secretion of adipokines (adiponectin, leptin, visfatin, and apelin) in adipocytes; these responses to CTRP3 are down-regulated by insulin resistance or inhibition of AMPK signaling.

Cow (Bovine) Apelin (APLN) Interaktionspartner

  1. APJ receptor (zeige APLNR Proteine) in granulosa cells and both apelin and the APJ receptor (zeige APLNR Proteine) in theca tissues are expressed in bovine ovary.

  2. The data suggest that apelin/APJ (zeige APLNR Proteine) system is involved in the mechanism regulating angiogenesis during follicle maturation as well as during corpora lutea formation and function in the bovine ovary.

Human Apelin (APLN) Interaktionspartner

  1. The apelin/APLNR (zeige APLNR Proteine) axis regulates cholangiocarcinoma cell proliferation and tumor angiogenesis.

  2. While plasma apelin increases in obesity, it decreases with increasing age and pubertal stage

  3. Increased plasma concentrations of apelin are associated with ST-segment elevation acute myocardial infarction severity.

  4. Data suggest that the differential expression of Apelin and Apelin receptor APJ (zeige APLNR Proteine) yields a "self-generated" gradient mechanisms that accelerates the extension of the sprout.

  5. Postmenopausal breast cancer patients had high levels of apelin and high BMI scores.

  6. For the first time, PRCP (zeige PRCP Proteine) is identified as an apelin-cleaving enzyme.

  7. The aim of this study was to evaluate if polymorphisms of APLN and APLNR (zeige APLNR Proteine) genes may play a role as susceptibility markers for hypertension in a group of Mexican-Mestizo patients.

  8. According to this study results, physicians may use initial apelin-12 levels which have a correlation with the disease severity calculated by SYNTAX score to stratify ST-elevation myocardial infarction patients to a high-risk group during hospitalization because of its level as an independent predictor of major adverse coronary event.s

  9. Six-month CT-apelin might be a valuable novel biomarker in identifying non-responders to cardiac resynchronization therapy that was superior to NT-proBNP

  10. high ACE (zeige ACE Proteine) and low apelin preoperatively have roles in CRP (zeige CRP Proteine) and MDA being increased postoperatively, which may be associated with postoperative atrial fibrillation after off pump coronary artery bypass grafting

Pig (Porcine) Apelin (APLN) Interaktionspartner

  1. Pig Apelin mRNA was sequenced.

Apelin (APLN) Protein Überblick

Protein Überblick

This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.

Alternative names and synonyms associated with Apelin (APLN)

  • apelin (apln)
  • apelin (APLN)
  • apelin (apln-b)
  • apelin (Apln)
  • apelin-like (LOC100625006)
  • apelin-like (LOC100346492)
  • 6030430G11Rik Protein
  • APEL Protein
  • APLN Protein
  • preproapelin Protein
  • Xapelin Protein
  • XNPEP2 Protein

Bezeichner auf Proteinebene für Apelin Proteine (APLN)

apelin , apelin, AGTRL1 ligand , preproapelin , preproapelin-b , APJ endogenous ligand , apelin; peptide ligand for APJ receptor , AGTRL1 ligand

798375 Danio rerio
611497 Canis lupus familiaris
741949 Pan troglodytes
100037057 Xenopus laevis
100038188 Xenopus (Silurana) tropicalis
30878 Mus musculus
282143 Bos taurus
8862 Homo sapiens
58812 Rattus norvegicus
101747811 Gallus gallus
100625006 Sus scrofa
100346492 Oryctolagus cuniculus
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