anti-RPS19 (RPS19) Antikörper

anti-Ribosomal Protein S19 Antikörper (RPS19)
Auf finden Sie aktuell 98 Ribosomal Protein S19 (RPS19) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RPS19 Proteine (24) und RPS19 Kits (14) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 143 RPS19 Produkte verfügbar.
DBA, DBA1, Dsk3, S19

Meistgesuchte Reaktivitäten zu anti-RPS19 (RPS19) Antikörper

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anti-Human RPS19 Antikörper:

anti-Mouse (Murine) RPS19 Antikörper:

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Am meisten referenzierte anti-RPS19 Antikörper

  1. Human Monoclonal RPS19 Primary Antibody für ELISA, WB - ABIN562734 : Rey, Duffy, Brown, Kennedy, Dick, Dror, Tailor: Enhanced alternative splicing of the FLVCR1 gene in Diamond Blackfan anemia disrupts FLVCR1 expression and function that are critical for erythropoiesis. in Haematologica 2008 (PubMed)
    Zeige alle 5 Referenzen für 562734

  2. Human Polyclonal RPS19 Primary Antibody für EIA, WB - ABIN954614 : Devlin, Dacosta, Mohandas, Elliott, Bodine: A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia. in Blood 2010 (PubMed)
    Zeige alle 5 Referenzen für 954614

  3. Human Polyclonal RPS19 Primary Antibody für ELISA, WB - ABIN185519 : Léger-Silvestre, Caffrey, Dawaliby, Alvarez-Arias, Gas, Bertolone, Gleizes, Ellis: Specific Role for Yeast Homologs of the Diamond Blackfan Anemia-associated Rps19 Protein in Ribosome Synthesis. in The Journal of biological chemistry 2005 (PubMed)

Weitere Antikörper gegen RPS19 Interaktionspartner

Human Ribosomal Protein S19 (RPS19) Interaktionspartner

  1. Reducing RPS19 in tumor cells or blocking the C5a receptor 1-RPS19 interaction decreases RPS19-mediated immunosuppression, impairs tumor growth, and delays the development of tumors in a transgenic model of breast cancer

  2. RPS19-downregulated erythroleukemia cells show reduced FLVCR1a and FLVCR1b mRNA levels associated with heme overload.

  3. Loss of RPS19 expression is associated with Diamond-Blackfan anemia.

  4. Mutations R62W and R101H impair RPS19 ability to associate with the ribosome.

  5. Data indicate that GATA1 (zeige GATA1 Antikörper) transcription factor is downregulated in ribosomal protein S19 (RPS19)-deficient cells through upregulation of TNF-alpha (zeige TNF Antikörper) and p38 MAPK (zeige MAPK14 Antikörper).

  6. RPS19 mutation is associated with Diamond Blackfan Anemia.

  7. A binding domain for RPS19 was identified and characterized in the N-terminus.

  8. increase of autophagy in cells derived from DBA patients, in CD34 (zeige CD34 Antikörper)+ erythrocyte progenitor cells with RPS19 knock down, in the red blood cells of zebrafish embryos with RP-deficiency, and in cells from patients with Shwachman-Diamond syndrome

  9. levels of branched-chain aminotransferase-1 (BCAT1 (zeige BCAT1 Antikörper)) transcripts are significantly decreased on the polysomes of both RPS19 and RPL11 (zeige RPL11 Antikörper) cells and that translation of BCAT1 (zeige BCAT1 Antikörper) protein is especially impaired in cells with small RP gene mutations

  10. High frequency of RPS19 gene deletion is associated with Italian Diamond-Blackfan anemia.

Mouse (Murine) Ribosomal Protein S19 (RPS19) Interaktionspartner

  1. Mutation of the key residue for extraribosomal function of ribosomal protein S19 cause increased grooming behaviors in mice. Results suggest an involvement of RP S19 (zeige ASAP1 Antikörper) oligomers in some anxiety-like behavior, especially grooming behavior.

  2. Rps19 mutant shows behavioural phenotypes resembling that of the human Diamond-Blackfan anaemia syndrome.

  3. indicate the importance of the RP S19 (zeige ASAP1 Antikörper) oligomer-induced macrophage recruitment in coagulum resorption

  4. Rps19 mutant embryonic stem cells showed significant increase in p53 (zeige TP53 Antikörper) protein expression.

  5. We report the generation of mouse models for RPS19-deficient Diamond Blackfan anemia using transgenic RNA interference that allows an inducible and graded down-regulation of Rps19.

  6. generated a transgenic model expressing an RPS19 mutation in which an arginine residue is replaced with a tryptophan residue at codon 62 as a model of Diamond-Blackfan anemia

  7. Combined Rps19 insufficiency and Pim-1 (zeige PIM1 Antikörper) deficiency promote murine myeloid cell growth through a deregulation of c-Myc (zeige MYC Antikörper) and a simultaneous up-regulation of anti-apoptotic Bcl proteins.

  8. RPS19 mRNA and protein expression were shown to decrease during terminal erythroid differentiation.

  9. Results indicate that ribosomal protein S19 (-/-) zygotes do not form blastocysts, whereas one normal Rps19 allele in mice is sufficient to maintain normal ribosomal and possibly extraribosomal functions.

  10. presence of an RP S19 (zeige ASAP1 Antikörper) dimer- and C5a receptor-mediated autocrine-type augmentation mechanism during Mn II-induced apoptosis in the mouse fibroblastic cell line

RPS19 Antigen-Profil

Beschreibung des Gens

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Alternative names and synonyms associated with RPS19

  • 30S ribosomal protein S19 (rps19) Antikörper
  • Protein RPS-19 (rps-19) Antikörper
  • ribosomal protein S19 (RPS19) Antikörper
  • ribosomal protein S19 (Rps19) Antikörper
  • DBA Antikörper
  • DBA1 Antikörper
  • Dsk3 Antikörper
  • S19 Antikörper

Bezeichner auf Proteinebene für RPS19

ribosomal protein S19 , 40S ribosomal protein S19

801541 Cyanophora paradoxa
2715642 Spinacia oleracea
172805 Caenorhabditis elegans
6223 Homo sapiens
476450 Canis lupus familiaris
516063 Bos taurus
20085 Mus musculus
29287 Rattus norvegicus
100169962 Felis catus
100173042 Pongo abelii
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