anti-CHUK (CHUK) Antikörper

anti-conserved Helix-Loop-Helix Ubiquitous Kinase Antikörper (CHUK)
Auf finden Sie aktuell 364 conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) Antikörper von 34 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CHUK Kits (10) und CHUK Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 394 CHUK Produkte verfügbar.
AI256658, CHUK, Chuk1, Fbx24, Fbxo24, IKBKA, ikk, IKK-alpha, IKK1, Ikka, ikkalpha, NFKBIKA, TCF16, zgc:56539
Alle Antikörper anzeigen Gen GeneID UniProt
CHUK 1147 O15111
CHUK 12675  
CHUK 309361  

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Alle verfügbaren anti-CHUK Antikörper

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Am meisten referenzierte anti-CHUK Antikörper

  1. Human Monoclonal CHUK Primary Antibody für ChIP, FACS - ABIN252647 : Manna, Mukhopadhyay, Aggarwal: IFN-alpha suppresses activation of nuclear transcription factors NF-kappa B and activator protein 1 and potentiates TNF-induced apoptosis. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Zeige alle 71 Referenzen für 252647

  2. Human Polyclonal CHUK Primary Antibody für WB - ABIN1881204 : Lahtela, Nousiainen, Stefanovic, Tallila, Viskari, Karikoski, Gentile, Saloranta, Varilo, Salonen, Kestilä: Mutant CHUK and severe fetal encasement malformation. in The New England journal of medicine 2010 (PubMed)
    Zeige alle 5 Referenzen für 1881204

  3. Human Polyclonal CHUK Primary Antibody für WB - ABIN1881203 : Gouin, Adib-Conquy, Balestrino, Nahori, Villiers, Colland, Dramsi, Dussurget, Cossart: The Listeria monocytogenes InlC protein interferes with innate immune responses by targeting the I{kappa}B kinase subunit IKK{alpha}. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Zeige alle 5 Referenzen für 1881203

  4. Human Monoclonal CHUK Primary Antibody für IP, WB - ABIN967550 : DiDonato, Hayakawa, Rothwarf, Zandi, Karin: A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. in Nature 1997 (PubMed)
    Zeige alle 5 Referenzen für 967550

  5. Human Monoclonal CHUK Primary Antibody für IF, WB - ABIN393762 : Li, Morgan, Choksi, Zhang, Kim, Liu: MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation. in Nature immunology 2010 (PubMed)
    Zeige alle 5 Referenzen für 393762

  6. Human Polyclonal CHUK Primary Antibody für IHC, ELISA - ABIN1531285 : Régnier, Song, Gao, Goeddel, Cao, Rothe: Identification and characterization of an IkappaB kinase. in Cell 1997 (PubMed)
    Zeige alle 3 Referenzen für 1531285

  7. Human Polyclonal CHUK Primary Antibody für IHC (p), WB - ABIN196836 : Yuan, Feldman, Sun, Olashaw, Coppola, Sussman, Shelley, Nicosia, Cheng: Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells. in The Journal of biological chemistry 2002 (PubMed)
    Zeige alle 2 Referenzen für 196836

  8. Human Polyclonal CHUK Primary Antibody für IHC (p), WB - ABIN197306 : Ozes, Mayo, Gustin, Pfeffer, Pfeffer, Donner: NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. in Nature 1999 (PubMed)
    Zeige alle 2 Referenzen für 197306

  9. Human Polyclonal CHUK Primary Antibody für ELISA, ICC - ABIN4324237 : Van Gammeren, Damrauer, Jackman, Kandarian: The IkappaB kinases IKKalpha and IKKbeta are necessary and sufficient for skeletal muscle atrophy. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009 (PubMed)
    Zeige alle 2 Referenzen für 4324237

  10. Human Polyclonal CHUK Primary Antibody für IF (p), IHC (p) - ABIN681508 : Huang, Yang, Wang, Ma, Cui, Huang, Sheng, Weng, Xu: Immunostimulatory activity of protein hydrolysate from oviductus ranae on macrophage in vitro. in Evidence-based complementary and alternative medicine : eCAM 2015 (PubMed)
    Zeige alle 2 Referenzen für 681508

Weitere Antikörper gegen CHUK Interaktionspartner

Human conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) Interaktionspartner

  1. IKKalpha promotes migration through dynamic interactions with the EGF (zeige EGF Antikörper) promoter depending on the redox state within cells.

  2. the dual regulation of STAT1 (zeige STAT1 Antikörper) by IKKalpha in antiviral signaling suggests a role for IKKalpha in the fine-tuning of antiviral signaling in response to non-self RNA.

  3. In epithelial ovarian cancer cells, miR (zeige MLXIP Antikörper)-23a enhances the expression of IKKalpha. The proliferation, migration, and invasion of EOC cells are increased by IKKalpha.

  4. TLR signaling led to lower expression of LRRC14 (zeige LRRC14 Antikörper).

  5. IKKalpha is an important determinant of poor outcome in patients with ER-positive invasive ductal breast cancer and thus may represent a potential therapeutic target

  6. The molecular mechanisms involved in IKKalpha-related tumors. [review]

  7. this study shows that miR (zeige MLXIP Antikörper)-23a regulated IL-17 (zeige IL17A Antikörper)-mediated proinflammatory mediators expression in rheumatoid arthritis by directly targeting IKKalpha

  8. W346 effectively inhibited tumor necrosis factor (TNF-a (zeige TNF Antikörper))-induced NF-kappaB (zeige NFKB1 Antikörper) activation by suppressing IKK phosphorylation, inhibiting IkB (zeige NFKBIB Antikörper)-a degradation, and restraining the accumulation of NF-kappaB (zeige NFKB1 Antikörper) subunit p65 (zeige GORASP1 Antikörper) nuclear translocation. W346 also affected NF-kappaB (zeige NFKB1 Antikörper)-regulated downstream products involved in cycle arrest and apoptosis.

  9. Data indicate a significantly higher quantity of mesenchymal stromal cells (MSCs)was produced from human embryonic stem cells (hESCs) with IkappaB kinase (IKK)/nuclear factor kappa B (NF-kappaB (zeige NFKB1 Antikörper)) suppression.

  10. Findings indicate that IkappaB kinase inhibitor ACHP (zeige LMBR1 Antikörper) can slowdown the accumulation of collagen type I (COL1A1 (zeige COL1A1 Antikörper)).

Mouse (Murine) conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) Interaktionspartner

  1. IKKalpha as a central mediator sensing both cytokine and microbial stimulation to suppress endoplasmic reticulum stress, thereby assuring antiinflammatory function during acute intestinal inflammation.

  2. The kinase IKKalpha inhibits activation of the transcription factor NF-kappaB (zeige NFKB1 Antikörper) by phosphorylating the regulatory molecule TAX1BP1 (zeige TAX1BP1 Antikörper).

  3. Data indicate that the inflammation and proliferation-related functions of I kappa B kinase (IKKbeta (zeige IKBKB Antikörper)) can be uncoupled by quinoxaline urea analog 13-197.

  4. Hematopoietic IKKalpha deficiency in mouse suppresses Akt (zeige AKT1 Antikörper) signaling, compromising monocyte/macrophage survival and this decreases early atherosclerosis.

  5. Anatomy of a negative feedback loop: the case of IkappaBalpha (zeige NFKBIA Antikörper).

  6. Epithelial-intrinsic IKK-alpha expression regulates group 3 innate lymphoid cell responses and antibacterial immunity.

  7. IKKalpha mediated the repair of the kidney via infiltrated regulatory T (Treg) cells, which can produce anti-inflammatory cytokine IL10 (zeige IL10 Antikörper)

  8. phosphorylation of DBC1 (zeige DBC1 Antikörper) at its C terminus by IKKalpha facilitates its interaction with RelB (zeige RELB Antikörper) and IKKalpha, indicating that DBC1 (zeige DBC1 Antikörper)-mediated suppression of alternative NF-kappaB (zeige NFKB1 Antikörper) is regulated by IKKalpha.

  9. IKKalpha controls the inflammasome at the level of the adaptor molecule ASC (zeige STS Antikörper), which interacts with IKKalpha in the nucleus of resting macrophages in an IKKalpha kinase-dependent manner.

  10. Stimulated BTK (zeige BTK Antikörper)-deficient dendritic cells are defective in the induction of IKK alpha/beta phosphorylation and IRF-1 (zeige IRF1 Antikörper) activation.

Zebrafish conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) Interaktionspartner

  1. These findings reveal a molecular mechanism regulating migration and invasion of epithelial cells and establish a key direct link between IKKbeta (zeige IKBKB Antikörper) and cell motility controlled by Rap (zeige LRPAP1 Antikörper)-integrin signaling.

  2. poky/chuk/ikk1 is required for differentiation of the zebrafish embryonic epidermis

  3. Ikk1 negatively regulates NF-kappaB (zeige NFKB1 Antikörper) by sequestering NEMO (zeige IKBKG Antikörper) from active IKK complexes, indicating that IKK1 can function as a repressor of NF-kappaB (zeige NFKB1 Antikörper).

CHUK Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

Alternative names and synonyms associated with CHUK

  • conserved helix-loop-helix ubiquitous kinase (chuk) Antikörper
  • conserved helix-loop-helix ubiquitous kinase (CHUK) Antikörper
  • conserved helix-loop-helix ubiquitous kinase (Chuk) Antikörper
  • AI256658 Antikörper
  • CHUK Antikörper
  • Chuk1 Antikörper
  • Fbx24 Antikörper
  • Fbxo24 Antikörper
  • IKBKA Antikörper
  • ikk Antikörper
  • IKK-alpha Antikörper
  • IKK1 Antikörper
  • Ikka Antikörper
  • ikkalpha Antikörper
  • NFKBIKA Antikörper
  • TCF16 Antikörper
  • zgc:56539 Antikörper

Bezeichner auf Proteinebene für CHUK

IKK-A , IKK-alpha , NFKBIKA , i kappa-B kinase alpha , ikBKA , inhibitor of nuclear factor kappa-B kinase subunit alpha , nuclear factor NF-kappa-B inhibitor kinase alpha , SPFH domain-containing protein 1 , conserved helix-loop-helix ubiquitous kinase , I-kappa-B kinase 1 , I-kappa-B kinase-alpha , IKK-a kinase , IkB kinase alpha subunit , Nuclear factor NFkappaB inhibitor kinase alpha , TCF-16 , transcription factor 16 , I kappa B kinase 1 , I-kappa-B kinase alpha , IKK alpha , IkappaB kinase alpha , ikappaB kinase , IkB kinase-a , IKK1 , IKKa , pky

444556 Xenopus laevis
450673 Pan troglodytes
477796 Canis lupus familiaris
709511 Macaca mulatta
100174735 Pongo abelii
1147 Homo sapiens
12675 Mus musculus
309361 Rattus norvegicus
423669 Gallus gallus
100135662 Sus scrofa
281073 Bos taurus
393287 Danio rerio
Ausgewählte Anbieter für anti-CHUK (CHUK) Antikörper
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