Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (N-Term) Peptid

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Proteinname
  • HGF
  • C230052L06Rik
  • HGF/SF
  • NK1
  • NK2
  • SF/HGF
  • HPTA
  • DFNB39
  • F-TCF
  • HGFB
  • SF
  • AI838057
  • HGFR
  • Par4
  • c-Met
  • hepatocyte growth factor
  • hepatocyte growth factor (hepapoietin A; scatter factor)
  • hepatocyte growth factor-like
  • met proto-oncogene
  • HGF
  • Hgf
  • LOC100525120
  • Met
Protein Region
N-Term
Spezies
Human
3
1
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
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Geblockter Antikörper anti-HGF Antikörper (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor)) (N-Term) (ABIN2781816)
Sequenz PFNSMSSGVK KEFGHEFDLY ENKDYIRNCI IGKGRSYKGT VSITKSGIKC
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-HGF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Hintergrund Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69- kDa alpha-chain and 34- kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.

Alias Symbols: HGF,HPTA,

Protein Size: 728
Molekulargewicht 79 kDa
Gen-ID 3082
NCBI Accession XP_006716019
UniProt P14210
Forschungsgebiet Angiogenesis, Growth Factors, Hormones, Cancer
Applikationshinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.