TWIST1 Proteine (TWIST1)

Bezeichnung:
Twist Homolog 1 (Drosophila) Proteine (TWIST1)
Auf www.antikoerper-online.de finden Sie aktuell 13 Twist Homolog 1 (Drosophila) (TWIST1) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TWIST1 Antikörper (159) und TWIST1 Kits (10) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 196 TWIST1 Produkte verfügbar.
Synonyme:
AA960487, ACS3, bHLHa38, BPES2, BPES3, CRS1, cTwist, M-Twist, MGC69439, Pde, pdt, SCS, Ska10, Ska, Twist, twist-1, twist1, Twist1b, wu:fd04c01, X-twi, Xtwi, Xtwist, zgc:101115
alle Proteine anzeigen Gen GeneID UniProt
TWIST1 7291 Q15672
Maus TWIST1 TWIST1 22160 P26687
Ratte TWIST1 TWIST1 85489  

Weitere Synonyme anzeigen

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Weitere Proteine zu TWIST1 Interaktionspartnern

Cow (Bovine) Twist Homolog 1 (Drosophila) (TWIST1) Interaktionspartner

  1. Frame-shift mutation in TWIST1 is associated with type 2 scurs syndrome.

Xenopus laevis Twist Homolog 1 (Drosophila) (TWIST1) Interaktionspartner

  1. Interaction with Snail1/2, and Twist function more generally, is regulated by GSK-3-beta-mediated phosphorylation of conserved sites in the WR domain.

Human Twist Homolog 1 (Drosophila) (TWIST1) Interaktionspartner

  1. SPZ1 (zeige SPZ1 Proteine) promotes epithelial-mesenchymal transition (EMT (zeige ITK Proteine))transition by trans-activating the gene of TWIST1. A clinical analysis showed a marker association of SPZ1 (zeige SPZ1 Proteine) and TWIST1 with induction of tumorigenesis in HCC (zeige FAM126A Proteine) patients.

  2. TrpC5 (zeige TRPC5 Proteine) induces the epithelial-mesenchymal transition through the HIF-1alpha (zeige HIF1A Proteine)-Twist signaling pathway to promote tumor metastasis in colon cancer.

  3. molecular and cellular processes that regulate dural Cerebral vein development in mammals and describe venous malformations in humans with craniosynostosis and TWIST1 mutations that are recapitulated in mouse models, are reported.

  4. this study shows that low Twist1 expression in idiopathic pulmonary fibrosis patients is associated with dysregulation of T cells, and that Twist1 may regulate inflammation (zeige CXCL12 Proteine)in fibrotic lung injury

  5. High TWIST1 expression is associated with breast cancer invasion and metastasis.

  6. Results found concomitant overexpression of MAGEA4 (zeige MAGEA4 Proteine) and TWIST1 in esophageal squamous cell carcinoma (ESCC). Also, it showed a correlation between MAGEA4 (zeige MAGEA4 Proteine) and TWIST1 expression, which was found as indirect binding of TWIST1 to the E-boxes in the MAGEA4 (zeige MAGEA4 Proteine) promoter revealing transcriptional upregulation of MAGEA4 (zeige MAGEA4 Proteine) by TWIST1.

  7. RNF8 (zeige RNF8 Proteine)-promoted Twist ubiquitination is required for Twist localization to the nucleus for subsequent epithelial-mesenchymal transition and cancer stem cells functions, thereby conferring chemoresistance.

  8. Twist1 appears to require both palladin (zeige PALLD Proteine) and collagen alpha1(VI) as downstream effectors for its prometastatic effects, which could be future therapeutic targets in cancer metastasis.

  9. Clinically, Twist transcript and protein expression was higher in areca quid chewing-associated Oral submucous fibrosis (OSF (zeige OSTF1 Proteine)) tissues than in normal oral mucosa tissues. This evidence suggests that upregulation of Twist might be involved in the pathogenesis of areca quid-associated OSF (zeige OSTF1 Proteine) through dysregulation of myofibroblast activity.

  10. This is the first study that links Twist1 in a feedback loop with its activating kinase, which indicates that concurrent inhibition of AURKA (zeige AURKA Proteine) and Twist1 will be synergistic in inhibiting pancreatic tumorigenesis and metastasis.

Mouse (Murine) Twist Homolog 1 (Drosophila) (TWIST1) Interaktionspartner

  1. molecular and cellular processes that regulate dural Cerebral vein development in mammals and describe venous malformations in humans with craniosynostosis and TWIST1 mutations that are recapitulated in mouse models, are reported.

  2. Methyltransferase G9A (zeige EHMT2 Proteine) Regulates Osteogenesis via Twist Gene Repression in mice.

  3. this study shows that loss of Twist1 in collagen-producing cells leads to increased bleomycin-induced pulmonary fibrosis, which is mediated by increased expression of CXCL12 (zeige CXCL12 Proteine)

  4. RNF8 (zeige RNF8 Proteine)-promoted Twist ubiquitination is required for Twist localization to the nucleus for subsequent epithelial-mesenchymal transition and cancer stem cells functions, thereby conferring chemoresistance.

  5. These results indicate that Twist1 Ser42 phosphorylation contributes to the pathogenesis of bleomycin-induced pulmonary fibrosis through angiopoietin-Tie2 (zeige TEK Proteine) signaling.

  6. the mesenchymal properties of the cranial mesoderm are likely to be regulated by a network of TWIST1 targets that influences the extracellular matrix and cell-matrix interactions, and collectively they are required for the morphogenesis of the craniofacial structures.

  7. TWIST1 expression promotes developmental angiogenesis by inducing endothelial cell proliferation and migration.

  8. There was a possible regulatory link between Twist 1 and PPARgamma (zeige PPARG Proteine) in 3T3-L1 mature adipocytes. This regulatory link enhanced the regulation of PPARgamma (zeige PPARG Proteine) and may be a functional mechanism of Twist 1 regulation of adipocyte physiology and pathology

  9. ur study revealed the dynamic Twist localization within the early stage of embryo. The results are discussed in terms of potential roles of Twist1 in the processes of lineage segregation, hatching, and implantation in post-compaction embryos and in blastocysts.

  10. findings demonstrate that Twist-1, which maintains BMSC at an immature state, endows them with an increased capacity for supporting hematopoiesis via direct activation of CXCL12 (zeige CXCL12 Proteine) gene expression.

Zebrafish Twist Homolog 1 (Drosophila) (TWIST1) Interaktionspartner

  1. the ventral migration of Cranial neural crest cells (CNCCs) away from a source of Bmps in the dorsal ectoderm promotes ectomesenchyme development by relieving Id2a-dependent repression of Twist1 function.

  2. twist1a and twist1b control skeletal development and dorsoventral patterning by regulating runx2b in zebrafish

  3. These observations are consistent with a role for twist1 in craniofacial, vertebral, and early renal development.

TWIST1 Protein Überblick

Protein Überblick

Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue\; in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.

Alternative names and synonyms associated with TWIST1

  • twist homolog 1 (Drosophila) (TWIST1)
  • twist homolog 1 (twist1)
  • twist basic helix-loop-helix transcription factor 1 (twist1-a)
  • twist basic helix-loop-helix transcription factor 1 (TWIST1)
  • twist basic helix-loop-helix transcription factor 1 (Twist1)
  • twist1a (twist1a)
  • AA960487 Protein
  • ACS3 Protein
  • bHLHa38 Protein
  • BPES2 Protein
  • BPES3 Protein
  • CRS1 Protein
  • cTwist Protein
  • M-Twist Protein
  • MGC69439 Protein
  • Pde Protein
  • pdt Protein
  • SCS Protein
  • Ska10 Protein
  • Ska Protein
  • Twist Protein
  • twist-1 Protein
  • twist1 Protein
  • Twist1b Protein
  • wu:fd04c01 Protein
  • X-twi Protein
  • Xtwi Protein
  • Xtwist Protein
  • zgc:101115 Protein

Bezeichner auf Proteinebene für TWIST1

twist homolog 1 , twist transcription factor , twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) , hypothetical protein , twist-like protein , twist-related protein 1 , T18 , X-twist , twist-related protein , B-HLH DNA binding protein , H-twist , TWIST homolog of drosophila , class A basic helix-loop-helix protein 38 , Pluridigite , Skam10Jus , charlie chaplin , polydactyly EMS , twist gene homolog 1 , twist 1 , twist homolog 1 (Drosophila)

GENE ID SPEZIES
100431892 Pongo abelii
395054 Xenopus (Silurana) tropicalis
574278 Macaca mulatta
782170 Bos taurus
378698 Xenopus laevis
7291 Homo sapiens
22160 Mus musculus
85489 Rattus norvegicus
395491 Gallus gallus
609156 Canis lupus familiaris
450135 Pan troglodytes
30175 Danio rerio
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