anti-KAT2B (KAT2B) Antikörper

Bezeichnung:
anti-K(lysine) Acetyltransferase 2B Antikörper (KAT2B)
Auf www.antikoerper-online.de finden Sie aktuell 106 K(lysine) Acetyltransferase 2B (KAT2B) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen KAT2B Proteine (11) und KAT2B Kits (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 126 KAT2B Produkte verfügbar.
Synonyme:
A930006P13Rik, AI461839, AW536563, CAF, gb:dq017634, im:7156024, P, p/CAF, Pcaf, si:ch211-1j13.2, zgc:161980
Alle Antikörper anzeigen Gen GeneID UniProt
KAT2B 8850 Q92831
KAT2B 18519 Q9JHD1
KAT2B 301164  

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-KAT2B (KAT2B) Antikörper

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anti-Human KAT2B Antikörper:

anti-Mouse (Murine) KAT2B Antikörper:

anti-Rat (Rattus) KAT2B Antikörper:

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Am meisten referenzierte anti-KAT2B Antikörper

  1. Human Polyclonal KAT2B Primary Antibody für EIA, WB - ABIN954021 : Perez, Knights, Sahu, Catania, Kolukula, Stoler, Graessmann, Ogryzko, Pishvaian, Albanese, Avantaggiati: Restoration of DNA-binding and growth-suppressive activity of mutant forms of p53 via a PCAF-mediated acetylation pathway. in Journal of cellular physiology 2010 (PubMed)
    Zeige alle 3 Referenzen für 954021

  2. Human Polyclonal KAT2B Primary Antibody für EIA, WB - ABIN954022 : Mooney, Goel, DAssoro, Salisbury, Janknecht: Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 3 Referenzen für 954022

  3. Human Polyclonal KAT2B Primary Antibody für WB - ABIN656013 : Xiong, Svingen, Sarmento, Smyrk, Dave, Khanna, Lomberk, Urrutia, Faubion: Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene. in American journal of physiology. Regulatory, integrative and comparative physiology 2014 (PubMed)

  4. Cow (Bovine) Polyclonal KAT2B Primary Antibody für WB - ABIN2787454 : Zeng, Zhang, Gerona-Navarro, Moshkina, Zhou: Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. in Structure (London, England : 1993) 2008 (PubMed)

  5. Cow (Bovine) Polyclonal KAT2B Primary Antibody für WB - ABIN2779660 : Chu, Tran, Ku, Crowe: Regulation of ERK1 gene expression by coactivator proteins. in The Biochemical journal 2005 (PubMed)

Weitere Antikörper gegen KAT2B Interaktionspartner

Human K(lysine) Acetyltransferase 2B (KAT2B) Interaktionspartner

  1. PCAF is a novel modulator of autophagy in hepatocellular carcinoma.

  2. a mechanism of transcriptional regulation mediated by p27 (zeige PAK2 Antikörper), Pax5 (zeige PAX5 Antikörper), and PCAF

  3. The studies identify a P/CAF-PAX3 (zeige PAX3 Antikörper)-FOXO1 (zeige FOXO1 Antikörper) signalling node that promotes oncogenesis and may contribute to MyoD (zeige MYOD1 Antikörper) dysfunction in Alveolar rhabdomyosarcoma (ARMS).

  4. results strongly support our hypothesis that PCAF is induced and activated by ATRA, and the subsequent acetylation of PCAF substrates promotes granulocytic differentiation in leukemia cells

  5. Our findings demonstrated a novel epigenetic mechanism of IL-10 (zeige IL10 Antikörper) dysregulation in inflammatory bowel disease. Down-regulation of KAT2B may disrupt the innate and adaptive inflammatory responses due to the suppression of this crucial anti-inflammatory cytokine.

  6. Acetyltransferase p300/CBP-associated factor (PCAF) interacts with and acetylates HOXB9 (zeige HOXB9 Antikörper) both in vivo and in vitro.

  7. Results suggest that increase in nuclear expression of p300 (zeige EP300 Antikörper), as well as the presence of cytoplasmic but loss of nuclear expression of p300/CBP-associated factor (PCAF), could play an important role in the development and progression of cutaneous squamous cell carcinomas (SCC (zeige CYP11A1 Antikörper)).

  8. Loss of p300 (zeige EP300 Antikörper) reduced repair of mismatches in DNA mismatch repair-deficient cells, but did not have evident effects on Base Excision Repair (BER) mechanisms, including the long patch BER pathway.

  9. Kat2b is a crucial transcriptional regulator for adaptive betaeta cell function during metabolic stress by controlling Unfolded Protein Response and represents a promising target for type 2 diabetes prevention and treatment.

  10. data define an essential motif cNM (zeige MTM1 Antikörper) in N-terminal E1A (zeige BCKDHA Antikörper) as an acetyl-CoA (zeige LPCAT2 Antikörper) entry blocker that directly associates with the entrance of acetyl-CoA (zeige LPCAT2 Antikörper) binding pocket to block the HAT (zeige MGEA5 Antikörper) domain access to its cofactor

Mouse (Murine) K(lysine) Acetyltransferase 2B (KAT2B) Interaktionspartner

  1. This study demonstrated that pcaf increase in skeletal muscle in muscle atrophy.

  2. Treatment with a pan (zeige SUPT6H Antikörper)-acetylase inhibitor, anacardic acid, reduced the binding affinity of p300 (zeige NOTCH1 Antikörper) and PCAF to the NKX2.5 (zeige NKX2-5 Antikörper), beta-MHC (zeige MYH7 Antikörper), Cx43 (zeige GJA1 Antikörper) promoters and attenuated H3K9 hyperacetylation.

  3. Gcn5 (zeige KAT2A Antikörper) and PCAF repress IFN-beta (zeige IFNB1 Antikörper) production in an enzymatic activity-independent and non-transcriptional manner: by inhibiting the innate immune signaling kinase TBK1 (zeige TBK1 Antikörper) in the cytoplasm.

  4. PCAF acetylates two lysine residues K328 and K450 in PGC-1alpha (zeige PPARGC1A Antikörper). PCAF in the obese mouse liver greatly represses gluconeogenic enzyme activation and glucose production and improves glucose homeostasis and insulin (zeige INS Antikörper) sensitivity.

  5. Study reveals that Gcn5 (zeige KAT2A Antikörper)/PCAF facilitate adipogenesis through regulation of PPARgamma (zeige PPARG Antikörper) expression and regulate brown adipogenesis by influencing Prdm16 (zeige PRDM16 Antikörper) expression.

  6. KLF10 (zeige KLF10 Antikörper), functions as a toggle to integrate antagonistic signals regulating FOXP3 (zeige FOXP3 Antikörper) via Sin3-HDAC (zeige HDAC3 Antikörper)/PCAF pathway and, thus, immune activation.

  7. PCAF is necessary for axonal regeneration and also promotes regeneration after spinal cord injury.

  8. These data unveil a p53 (zeige TP53 Antikörper)/PCAF/Gli1 (zeige GLI1 Antikörper) circuitry centered on PCAF that limits Gli1 (zeige GLI1 Antikörper)-enhanced mitogenic and prosurvival response.

  9. PCAF is an important regulator for promoting osteoblast differentiation via acetylation modification of Runx2 (zeige RUNX2 Antikörper).

  10. CSB (zeige ERCC6 Antikörper) and PCAF play cooperative roles to establish the active state of rRNA genes by histone acetylation

KAT2B Antigen-Profil

Beschreibung des Gens

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Alternative names and synonyms associated with KAT2B

  • K(lysine) acetyltransferase 2B (KAT2B) Antikörper
  • K(lysine) acetyltransferase 2B (kat2b) Antikörper
  • K(lysine) acetyltransferase 2A (kat2a) Antikörper
  • K(lysine) acetyltransferase 2B (Kat2b) Antikörper
  • p300/CBP-associated factor (Pcaf) Antikörper
  • A930006P13Rik Antikörper
  • AI461839 Antikörper
  • AW536563 Antikörper
  • CAF Antikörper
  • gb:dq017634 Antikörper
  • im:7156024 Antikörper
  • P Antikörper
  • p/CAF Antikörper
  • Pcaf Antikörper
  • si:ch211-1j13.2 Antikörper
  • zgc:161980 Antikörper

Bezeichner auf Proteinebene für KAT2B

p300/CBP-associated factor , histone acetyltransferase KAT2B , PCAF , CREBBP-associated factor , histone acetylase PCAF , histone acetyltransferase PCAF , lysine acetyltransferase 2B , K(lysine) acetyltransferase 2B

GENE ID SPEZIES
460219 Pan troglodytes
563942 Danio rerio
100061976 Equus caballus
555517 Danio rerio
428441 Gallus gallus
8850 Homo sapiens
477052 Canis lupus familiaris
407215 Bos taurus
18519 Mus musculus
100626923 Sus scrofa
301164 Rattus norvegicus
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