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Transducer of ERBB2, 2 Proteine (TOB2)

Transducer of ERBB2, 2 Proteine (TOB2)
Auf finden Sie aktuell 4 Transducer of ERBB2, 2 (TOB2) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Transducer of ERBB2, 2 Antikörper (37) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 45 Transducer of ERBB2, 2 Produkte verfügbar.
2900090N22Rik, 4930545K18Rik, AV071822, mKIAA1663, tob2, TOB4, TOBL, TROB2
alle Proteine anzeigen Gen GeneID UniProt
Ratte TOB2 TOB2 315159  
TOB2 10766 Q14106
TOB2 57259 Q9JM55

Weitere Synonyme anzeigen

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Weitere Proteine zu Transducer of ERBB2, 2 Interaktionspartnern

Human Transducer of ERBB2, 2 (TOB2) Interaktionspartner

  1. Results show reduced Tob2 expression in primary hepatocellular Carcinoma cells (HCC (zeige FAM126A Proteine)) and that dysregulation of miR (zeige MLXIP Proteine)-362 and Tob2 may contribute to HCC (zeige FAM126A Proteine) malignancy.

  2. The antiproliferative and the mRNA deadenylation/decay-promoting effects of TOB1 and TOB2 proteins are linked.

  3. study identifies miR-378-TOB2-cyclin D1 as a functional module to mediate the cross talk between Myc and Ras signaling in cellular transformation

  4. TNFalpha (zeige TNF Proteine) is able to transactivate ErbB-2 (zeige ERBB2 Proteine) and use it as an obligatory downstream signaling molecule in the generation of mitogenic signals.

  5. Haploinsufficiency of the MLL (zeige MLL Proteine) and TOB2 genes in lymphoid malignancy.

  6. Antiproliferative proteins of the BTG/Tob (zeige TDO2 Proteine) family are degraded by the ubiquitin-proteasome system. the C-terminal regions are necessary and sufficient to control the stabilities of BTG1 (zeige BTG1 Proteine), BTG2 (zeige BTG2 Proteine), Tob (zeige TDO2 Proteine), and Tob2 proteins.

Mouse (Murine) Transducer of ERBB2, 2 (TOB2) Interaktionspartner

  1. Tob1(-/-), Tob2(-/-), and Tob1/2 double knockout (DKO, Tob1(-/-) & Tob2(-/-)) embryonic stem cells (ESCs (zeige NR2E3 Proteine)) grew faster than wild type (WT) ESCs (zeige NR2E3 Proteine) without losing pluripotency.

  2. miR (zeige MLXIP Proteine)-322 and its target protein Tob2 modulate Osx (zeige SP7 Proteine) mRNA stability

  3. Tob2 protein suppresses PPARgamma2 (zeige PPARG Proteine) transcription by inhibiting BMP2 (zeige BMP2 Proteine)-induced Smad1 (zeige SMAD1 Proteine)/5 phosphorylation through its interaction with Smad6 (zeige SMAD6 Proteine) and by sequestering C/EBPalpha (zeige CEBPA Proteine) from the PPARgamma2 (zeige PPARG Proteine) promoter.

  4. Tob2 negatively regulates formation of osteoclasts by suppressing RANKL (zeige TNFSF11 Proteine) expression through its interaction with vitamin D receptor (zeige VDR Proteine)

Transducer of ERBB2, 2 (TOB2) Protein Überblick

Protein Überblick

TOB2 belongs to the TOB (see TOB1\; MIM 605523)/BTG1 (MIM 109580) family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.

Alternative names and synonyms associated with Transducer of ERBB2, 2 (TOB2)

  • transducer of ERBB2, 2 (Tob2)
  • transducer of ERBB2, 2 (TOB2)
  • transducer of ERBB2, 2 (tob2)
  • 2900090N22Rik Protein
  • 4930545K18Rik Protein
  • AV071822 Protein
  • mKIAA1663 Protein
  • tob2 Protein
  • TOB4 Protein
  • TOBL Protein
  • TROB2 Protein

Bezeichner auf Proteinebene für Transducer of ERBB2, 2 Proteine (TOB2)

protein Tob2 , transducer of ERBB2, 2 , protein Tob4 , transducer of erbB-2 2

315159 Rattus norvegicus
458865 Pan troglodytes
548967 Xenopus (Silurana) tropicalis
707216 Macaca mulatta
10766 Homo sapiens
417992 Gallus gallus
481233 Canis lupus familiaris
507934 Bos taurus
57259 Mus musculus
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