KCNJ5 Proteine (KCNJ5)

Auf www.antikoerper-online.de finden Sie aktuell 9 Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen KCNJ5 Antikörper (55) und KCNJ5 Kits (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 76 KCNJ5 Produkte verfügbar.
cir, GIRK4, KATP1, Kir3.4, LQT13, xcir
alle Proteine anzeigen Gen GeneID UniProt
KCNJ5 9541 Q86X95
KCNJ5 16521 P48545
KCNJ5 29713 P48548

KCNJ5 Proteine (KCNJ5) nach Spezies

Weitere Proteine zu KCNJ5 Interaktionspartnern

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5) Interaktionspartner

  1. These findings expand on the clinical spectrum of phenotypes associated with KCNJ5 mutations and implicate these mutations in the pathogenesis of hypertension associated with increased aldosterone response to ACTH (zeige POMC Proteine) stimulation.

  2. KCNJ5 mutations predominate in large zona fasciculata (ZF)-like Aldosterone-producing Adenomas.

  3. Mutations in KCNJ5 cause the excessive autonomous aldosterone secretion of Aldosterone-producing Adenomas.

  4. KCNJ5 genetic mutation plays a role in the development of primary aldosteronism in aldosterone producing adenomas.

  5. Study provides new evidence, indicating that some glutamate receptor ionotropic kainate 4 (zeige GRIK4 Proteine) variants modulate the response to electroconvulsive therapy in patients with depression resistant to treatment, suggesting a role for kainate receptor modulation.

  6. documented for the first time the expression of inflammation-related genes in aldosterone-producing adenomas (APAs) and the correlation of their expression levels with the KCNJ5 mutation status and mRNA expression levels of steroidogenic enzymes, indicating the pathophysiological relevance of inflammation-related genes in APAs

  7. GIRK1 (zeige KCNJ3 Proteine)/GIRK4 hetero-tetramers are not activated by Na+, but rather are in a permanent state of high responsiveness to G proteins beta-gamma, suggesting that the GIRK1 (zeige KCNJ3 Proteine) subunit functions like a GIRK4 subunit with Na+ permanently bound.

  8. japanese Aldosterone-Producing Adenoma patients may have distinct features including a higher prevalence of KCNJ5 mutations, no gender difference in the frequency of these mutations, and characteristics similar to the zona glomerulosa.

  9. Novel somatic KCNJ5 variants likely cause adenomas by loss of potassium selectivity, similar to previously described mutations.

  10. KCNJ5 mutations in aldosterone-producing adenomas are more frequent in women; however, this gender dimorphism is a reported phenomenon of Western but not East Asian populations (review).

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5) Interaktionspartner

  1. These results provide a novel molecular mechanism for autocrine negative feedback regulation of insulin (zeige INS Proteine) secretion.

  2. study establishes the role of f-channels in cardiac automaticity and indicates that arrhythmia related to HCN loss-of-function may be managed by pharmacological or genetic inhibition of GIRK4 channels

  3. Data indicate taht m2R-RGS6 (zeige RGS6 Proteine)-IKACh pathway sets heart rate variability independently from the autonomic input.

  4. Therefore, the lack of proper functioning of the cardio-protective K(ATP) system in the mdx (zeige DMD Proteine) cardiomyocytes may be part of the mechanism contributing to development of cardiac disease in dystrophic patients.

  5. Data suggest HL-1 (zeige ASGR1 Proteine) cells express GIRK1 (zeige KCNJ3 Proteine)/4 and M2 muscarinic receptors and are a good model to study acetylcholine-activated potassium currents.

  6. Data show that the composition of the Kir3.1 (zeige KCNJ3 Proteine) and Kir (zeige GEM Proteine) 3.4 subunits of the G protein-gated potassium channel (zeige KCNAB2 Proteine) changes during embryonic development.

  7. These data implicate GIRK4-containing channels in signaling crucial to energy homeostasis and body weight.

Pig (Porcine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5) Interaktionspartner

  1. Blockade of K(ATP) channels further diminished (approximately 45%) the repayment of flow debt (zeige PLXNB2 Proteine) in lean but not metabolic syndrome swine.

KCNJ5 Protein Überblick

Protein Überblick

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.

Alternative names and synonyms associated with KCNJ5

  • corepressor interacting with RBPJ, 1 (CIR1)
  • corepressor interacting with RBPJ, 1 (cir1)
  • potassium inwardly-rectifying channel, subfamily J, member 5 (KCNJ5)
  • potassium inwardly-rectifying channel, subfamily J, member 5 (Kcnj5)
  • cir Protein
  • GIRK4 Protein
  • KATP1 Protein
  • Kir3.4 Protein
  • LQT13 Protein
  • xcir Protein

Bezeichner auf Proteinebene für KCNJ5

CBF1 interacting corepressor , CBF1-interacting corepressor , corepressor interacting with RBPJ 1 , recepin , G protein-activated inward rectifier potassium channel 4 , IRK-4 , cardiac ATP-sensitive potassium channel , heart KATP channel , inward rectifier K+ channel KIR3.4 , CIR , GIRK-4 , KATP-1 , cardiac inward rectifier , inward rectifier K(+) channel Kir3.4 , potassium channel, inwardly rectifying subfamily J member 5 , GIRK4 , inward rectifying K channel , potassium inwardly-rectifying channel J5

9541 Homo sapiens
446936 Xenopus laevis
426529 Gallus gallus
3762 Homo sapiens
16521 Mus musculus
29713 Rattus norvegicus
395925 Gallus gallus
489284 Canis lupus familiaris
397448 Sus scrofa
100352473 Oryctolagus cuniculus
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