TNFSF13B Proteine (TNFSF13B)

Tumor Necrosis Factor (Ligand) Superfamily, Member 13b Proteine (TNFSF13B)
Auf finden Sie aktuell 78 Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) Proteine von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TNFSF13B Antikörper (306) und TNFSF13B Kits (60) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 462 TNFSF13B Produkte verfügbar.
BAFF, BLyS, CD257, D8Ertd387e, DTL, RGD1561519, TALL-1, TALL1, THANK, TNFSF13B, TNFSF20, zTNF4
alle Proteine anzeigen Gen GeneID UniProt
TNFSF13B 498666  
TNFSF13B 10673 Q9Y275
TNFSF13B 24099 Q9WU72

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Am meisten referenzierte TNFSF13B Proteine

  1. Human TNFSF13B Protein expressed in CHO Cells - ABIN2666541 : Nardelli, Belvedere, Roschke, Moore, Olsen, Migone, Sosnovtseva, Carrell, Feng, Giri, Hilbert: Synthesis and release of B-lymphocyte stimulator from myeloid cells. in Blood 2001 (PubMed)
    Zeige alle 8 Referenzen für 2666541

  2. Mouse (Murine) TNFSF13B Protein expressed in CHO Cells - ABIN2666770 : Koizumi, Hiasa, Kumagi, Yamanishi, Azemoto, Kobata, Matsuura, Abe, Onji: Increased B cell-activating factor promotes tumor invasion and metastasis in human pancreatic cancer. in PLoS ONE 2013 (PubMed)
    Zeige alle 8 Referenzen für 2666770

  3. Human TNFSF13B Protein expressed in Escherichia coli (E. coli) - ABIN1344400 : Bossen, Cachero, Tardivel, Ingold, Willen, Dobles, Scott, Maquelin, Belnoue, Siegrist, Chevrier, Acha-Orbea, Leung, Mackay, Tschopp, Schneider: TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts. in Blood 2008 (PubMed)
    Zeige alle 2 Referenzen für 1344400

  4. Cynomolgus TNFSF13B Protein expressed in Human Cells - ABIN3216414 : Oren, Li, Volovik, Morris, Dharia, Das, Galperina, Gentz, Arnold: Structural basis of BLyS receptor recognition. in Nature structural biology 2002 (PubMed)

  5. Human TNFSF13B Protein expressed in HEK-293 Cells - ABIN1344293 : Huard, Tran, Benkhoucha, Manzin-Lorenzi, Santiago-Raber: Selective APRIL blockade delays systemic lupus erythematosus in mouse. in PLoS ONE 2012 (PubMed)

Weitere Proteine zu TNFSF13B Interaktionspartnern

Horse (Equine) Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) Interaktionspartner

  1. Equine adipose-derived stem cell (ASC (zeige PYCARD Proteine)) expresses BAFF (TNFSF13B) and its receptors, which may be associated with the differentiation process of ASC (zeige PYCARD Proteine) towards adipocyte.

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) Interaktionspartner

  1. this study provides new useful information about the increased levels of BAFF observed during HIV-1 infection and highlights the importance of macrophages as a source of BAFF

  2. The novel association between BAFF and inflammatory bowel disease (IBD) seems to identify that BAFF might regulate the inflammatory process in these diseases and it appears to be a potential marker of IBD.

  3. In BAFF, rs2893321 may be a susceptible genetic variant for the development of GD and AITDs. Associations of rs2893321 with susceptibility to GD and AITDs and the correlation between rs2893321 and TAb exhibit a dimorphic pattern. Additional studies with larger sample sizes are required to confirm our findings.

  4. BAFF and IL-17A (zeige IL17A Proteine) are associated with different subphenotypes of primary Sjogren's syndrome.

  5. The expression levels of serum BAFF and the three receptors (TACI (zeige TNFRSF13B Proteine), BCMA (zeige TNFRSF17 Proteine) and BAFF-R (zeige TNFRSF13C Proteine)) in non-Hodgkin lymphoma patients were significantly higher than in healthy controls.

  6. Plasma BAFF levels were positively associated with serum creatinine, proteinuria, uric acid and group A Streptococcus infection index in patients with IgA nephropathy.

  7. this study shows that chicoric acid suppresses BAFF expression by inhibiting NF-kappaB (zeige NFKB1 Proteine) activity, and chicoric acid may serve as a novel therapeutic agent to down-regulate excessive BAFF expression in autoimmune diseases

  8. Findings indicate that BAFF expression is significantly increased in chronic rhinosinusitis with nasal polyps patients and may orchestrate inflammatory load in polyp tissues by regulating T and B cell-mediated response.

  9. Urinary APRIL (uAPRIL) and BAFF (uBAFF) levels were raised significantly in AN.

  10. During remission, serum CXCL13 (zeige CXCL13 Proteine) and BAFF levels have not decreased to normal in neuromyelitis optica patients, and B-cell-related autoimmune response persists. Immunosuppressive therapy decreased serum BAFF levels, but did not affect CXCL13 (zeige CXCL13 Proteine) expression.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) Interaktionspartner

  1. This study suggests that BAFF selects IL-10 (zeige IL10 Proteine)(-)B cells over IL-10 (zeige IL10 Proteine)(+) regulatory B cells via BAFF receptors in inflammatory responses

  2. BAFF plays a previously unappreciated role in lupus nephritis by inducing renal tertiary lymphoid structures and regulating the position of T cells within the glomeruli.

  3. this study shows that BAFF overexpression reduces hypercholesterolemia and atherosclerosis in hyperlipidemic mice via TACI (zeige TNFRSF13B Proteine)-dependent B cell activation (zeige BLNK Proteine)

  4. B cell-activating factor (BAFF) upregulates CD28 (zeige CD28 Proteine)/B7 and CD40 (zeige CD40 Proteine)/CD154 (zeige CD40LG Proteine) expression, and promotes the interactions between T and B cells in a BAFF receptor (zeige TNFRSF13C Proteine)-dependent manner.

  5. findings highlight a novel mechanism through which BAFF promotes humoral autoimmunity via direct, TACI (zeige TNFRSF13B Proteine)-dependent activation of transitional B cells

  6. neutrophils secreted a B cell-activating factor that highly accelerated plasma cell generation and antigen-specific antibody production.

  7. The enhanced thermogenic program was confirmed by higher protein levels of UCP1 (zeige UCP1 Proteine) and irisin (zeige FNDC5 Proteine) in female BAFF-/- than in WT mice.

  8. Antibodies That Block or Activate Mouse B Cell Activating Factor of the Tumor Necrosis Factor (TNF (zeige TNF Proteine)) Family (BAFF), Respectively, Induce B Cell Depletion or B Cell Hyperplasia.

  9. Increased B-cell activating factor (BAFF) induced B cell differentiation into germinal center (GC) B (zeige NPR2 Proteine) cells within the autoimmune target tissue.

  10. The Tnfas13b in the hippocampus in the prefrontal cortex of the DBA (zeige RPS19 Proteine)/2 J strain were up-regulated.

Pig (Porcine) Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) Interaktionspartner

  1. study reports the molecular cloning, expression and bioactivity of the porcine homologue of human BAFF

  2. This study demonstrated expression of BAFF on cultured monocyte-derived dendritic cells, which was further enhanced by interferon-alpha (zeige IFNA Proteine) or interferon-gamma (zeige IFNG Proteine) treatment.

Rabbit Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) Interaktionspartner

  1. Although BAFF expression is dispensable for B cell development in the bone marrow, it is required for B cell development in gut (zeige GUSB Proteine)-associated lymphoid tissue.

  2. BAFF and its receptors during B-cell activation (zeige BLNK Proteine) and autoantibody production in rabbits derived from selective breeding to develop a reproducible rabbit model of Systemic Lupus Erythematosus, were investigated.

  3. Cloning and expression analysis of B-cell activating factor (BAFF) provide the basis for investigation of its role in regulating rabbit B-lymphocyte (zeige AKAP17A Proteine) development and immune responses.

  4. BAFF was detected in developing appendix of young rabbits by immunohistochemical staining suggesting that BAFF plays a role during the period following birth when rabbit B-cell development is occurring.

TNFSF13B Protein Überblick

Protein Überblick

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Alternative names and synonyms associated with TNFSF13B

  • tumor necrosis factor (ligand) superfamily, member 13b (Tnfsf13b)
  • tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B)
  • BAFF Protein
  • BLyS Protein
  • CD257 Protein
  • D8Ertd387e Protein
  • DTL Protein
  • RGD1561519 Protein
  • TALL-1 Protein
  • TALL1 Protein
  • THANK Protein
  • TNFSF13B Protein
  • TNFSF20 Protein
  • zTNF4 Protein

Bezeichner auf Proteinebene für TNFSF13B

tumor necrosis factor ligand superfamily member 13B , tumor necrosis factor (ligand) superfamily, member 13b , B-cell activating factor , B-lymphocyte stimulator , TNF- and APOL-related leukocyte expressed ligand 1 , ApoL related ligand TALL-1 , B-cell-activating factor , Delta4 BAFF , TNF and ApoL-related leukocyte expressed ligand 1 , TNF homolog that activates apoptosis , delta BAFF , dendritic cell-derived TNF-like molecule , tumor necrosis factor (ligand) superfamily, member 20 , tumor necrosis factor-like protein ZTNF4 , b cell-activating factor , tumor necrosis factor superfamily member 13b

498666 Rattus norvegicus
467323 Pan troglodytes
485545 Canis lupus familiaris
504507 Bos taurus
693917 Macaca mulatta
100051550 Equus caballus
10673 Homo sapiens
24099 Mus musculus
100038026 Sus scrofa
100101577 Oryctolagus cuniculus
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