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TGFA Proteine (TGFA)

Transforming Growth Factor, alpha Proteine (TGFA)
Auf finden Sie aktuell 45 Transforming Growth Factor, alpha (TGFA) Proteine von 14 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TGFA Antikörper (351) und TGFA Kits (84) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 488 TGFA Produkte verfügbar.
LOC100009482, NV15606, RATTGFAA, TFGA, TGFA, TGFAA, TGF alpha, wa-1, wa1
alle Proteine anzeigen Gen GeneID UniProt
TGFA 24827 P01134
TGFA 21802 P48030
TGFA 7039 P01135

Weitere Synonyme anzeigen

TGFA Proteine (TGFA) nach Spezies

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Am meisten referenzierte TGFA Proteine

  1. Human TGFA Protein expressed in Escherichia coli (E. coli) - ABIN2667579 : DeglInnocenti, Alberti, Castellano, Greco, Miranda, Pierotti, Seregni, Borrello, Canevari, Tomassetti: Integrated ligand-receptor bioinformatic and in vitro functional analysis identifies active TGFA/EGFR signaling loop in papillary thyroid carcinomas. in PLoS ONE 2010 (PubMed)
    Zeige alle 6 Referenzen für ABIN2667579

  2. Human TGFA Protein expressed in Escherichia coli (E. coli) - ABIN2666940 : Juanes, Ferreira, Montero, Arribas, Pandiella: N-terminal cleavage of proTGFalpha occurs at the cell surface by a TACE-independent activity. in The Biochemical journal 2005 (PubMed)
    Zeige alle 6 Referenzen für ABIN2666940

Weitere Proteine zu TGFA Interaktionspartnern

Mouse (Murine) Transforming Growth Factor, alpha (TGFA) Interaktionspartner

  1. c-Myc (zeige MYC Proteine) and transforming growth factor alpha enhance the development of hepatic lesions due to mutant beta-catenin (zeige CTNNB1 Proteine) in transgenic mice.

  2. Reverse transcriptase polymerase chain reaction studies showed that three members, Tgfa, Hbegf,and Nrg1 of the EGF family were expressed in the epithelium cultured with FGF7 + LPA as well as in the epithelium freshly isolated from the rudiments.

  3. findings suggest that elevated PHD4 (zeige P4HTM Proteine) levels disturb the angiogenic balance in osteosarcoma via induction of the TGF-alpha pathway and inhibit tumor growth by reducing the expression of HIF-2alpha (zeige EPAS1 Proteine)

  4. Interaction between IRF6 (zeige IRF6 Proteine) and TGFA genes contribute to the risk of nonsyndromic cleft lip/palate.

  5. These results imply that TGFalpha stimulates proliferation of endometrial stromal cells through multiple mechanisms, including its regulation of Igfbp3 (zeige IGFBP3 Proteine) and Mmp3 (zeige MMP3 Proteine) transcription.

  6. ADAM-17 (zeige ADAM17 Proteine) and TGF-alpha are strongly and locally upregulated following adult mice cortical damage.

  7. Different mechanisms regulate neurogenesis in neonatal and adult olfactory epithelium; fibroblast growth factor (FGF)2 (zeige FGF2 Proteine) and TGFalpha may have different roles throughout development.

  8. beta-catenin (zeige CTNNB1 Proteine) controlled both cell-autonomous and non-cell-autonomous hepatocyte proliferation, through direct transcriptional and complex control of cyclin D1 (zeige CCND1 Proteine) gene expression and of the expression of a new target gene, Tgfalpha.

  9. variable TGF-alpha expression may explain, in part, the genetic susceptibility to chronic kidney disease (CKD) progression.

  10. This may be the first report of the expression of carcinogenesis-related molecules such as EGFR (zeige EGFR Proteine), K-ras (zeige HRAS Proteine), Cox2 and TGFalpha during chronic pancreatitis.

Human Transforming Growth Factor, alpha (TGFA) Interaktionspartner

  1. In conclusion, we identified four novel loci (TGFA, PIK3R1, FGFR3 (zeige FGFR3 Proteine) and TREH (zeige TREH Proteine)) and confirmed two loci known to be associated with cartilage thickness.The identified associations were not caused by rare exonic variants. This is the first report linking TGFA to human Osteoarthritis, which may serve as a new target for future therapies.

  2. Our study showed that TGFA/TGFB3 (zeige TGFB3 Proteine)/MSX1 (zeige MSX1 Proteine) gene polymorphisms were associated with congenital NSHI. The distribution of genotype frequencies and allele frequencies of TGFA rs3771494, TGFB3 (zeige TGFB3 Proteine) rs3917201 and rs2268626, and MSX1 (zeige MSX1 Proteine) rs3821949 and rs62636562 were significantly different between the case and the control groups

  3. TGFA gene expression is regulated by MiR (zeige MLXIP Proteine)-374a in lung adenocarcinoma.TGFA plays role in lung adenocarcinoma cell proliferation and invasion.

  4. Overall, our findings indicated that intratumoral administration of TGFalphaL3-SEB effectively inhibited the growth of breast tumors through induction of necrosis and suppressing proliferation and angiogenesis without systemic toxicity.

  5. TGFA expression decreased after 10 and 30min of treatment even when transcription was not inhibited. We found that activation of PI3K (zeige PIK3CA Proteine) was necessary for triiodothyronine to modulate HIF1A (zeige HIF1A Proteine) and TGFA expression

  6. This is the first demonstration that miR (zeige MLXIP Proteine)-490-3P might act as a suppressor in endometrial cancer tumorigenesis and progression by targeting TGFalpha.

  7. miR (zeige MLXIP Proteine)-505 acts as tumor suppressor in endometrial cancer by regulating TGF-alpha.

  8. findings strongly suggest that phosphorylated HSP20 (zeige HSPB6 Proteine) inhibits TGF-alpha-induced HCC (zeige FAM126A Proteine) cell migration and invasion via suppression of the JNK (zeige MAPK8 Proteine) signaling pathway

  9. miR (zeige MLXIP Proteine)-205 may function as a tumor suppressor via targeting TGF-alpha in Osteosarcoma

  10. our data suggest that the anti-inflammatory actions of paricalcitol in tubular cells could depend on the inhibition of TGF-a/ADAM17 (zeige ADAM17 Proteine)/EGFR (zeige EGFR Proteine) pathway in response to aldosterone, showing an important mechanism of VDRAs action.

Pig (Porcine) Transforming Growth Factor, alpha (TGFA) Interaktionspartner

  1. upregulation of TGFalpha or FGF2 (zeige FGF2 Proteine) expression is not a pre-requisite for enhanced testicular growth and increased Sertoli cell proliferation that occurs subsequent to hemicastration in the neonatal boar

TGFA Protein Überblick

Protein Überblick

This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TGFA

  • transforming growth factor, alpha (tgfa)
  • transforming growth factor, alpha (TGFA)
  • transforming growth factor alpha (LOC100009482)
  • transforming growth factor alpha (LOC100121300)
  • transforming growth factor alpha (Tgfa)
  • transforming growth factor alpha (TGF-A)
  • transforming growth factor-alpha (LOC100009150)
  • transforming growth factor, alpha (LOC100358936)
  • LOC100009482 Protein
  • NV15606 Protein
  • RATTGFAA Protein
  • TFGA Protein
  • TGFA Protein
  • TGFAA Protein
  • TGF alpha Protein
  • wa-1 Protein
  • wa1 Protein

Bezeichner auf Proteinebene für TGFA

transforming growth factor, alpha , transforming growth factor alpha , protransforming growth factor alpha , transforming growth factor-alpha , waved 1 , TGF alpha , TGF-alpha

496037 Xenopus laevis
737080 Pan troglodytes
100009482 Oryctolagus cuniculus
100121300 Nasonia vitripennis
100172994 Pongo abelii
24827 Rattus norvegicus
21802 Mus musculus
443307 Ovis aries
100009150 Oryctolagus cuniculus
7039 Homo sapiens
613031 Macaca mulatta
397484 Sus scrofa
100358936 Oryctolagus cuniculus
403431 Canis lupus familiaris
540388 Bos taurus
414743 Gallus gallus
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