anti-MAP3K14 (MAP3K14) Antikörper

Bezeichnung:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 14 Antikörper (MAP3K14)
Auf www.antikoerper-online.de finden Sie aktuell 132 Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP3K14 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 153 MAP3K14 Produkte verfügbar.
Synonyme:
aly, F23F1.4, F23F1_4, FLH21957, FTDCR1B, HGK, HS, HSNIK, MEKKK4, mitogen-activated protein kinase kinase kinase 14, Nik
Alle Antikörper anzeigen Gen GeneID UniProt
MAP3K14 9020 Q99558
MAP3K14 360640  
MAP3K14 53859 Q9WUL6

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Meistgesuchte Reaktivitäten zu anti-MAP3K14 (MAP3K14) Antikörper

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anti-Human MAP3K14 Antikörper:

anti-Rat (Rattus) MAP3K14 Antikörper:

anti-Mouse (Murine) MAP3K14 Antikörper:

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Am meisten referenzierte anti-MAP3K14 Antikörper

  1. Human Polyclonal MAP3K14 Primary Antibody für WB - ABIN392539 : Bouzakri, Zierath: MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance. in The Journal of biological chemistry 2007 (PubMed)
    Zeige alle 4 Referenzen für 392539

  2. Mouse (Murine) Polyclonal MAP3K14 Primary Antibody für WB - ABIN658077 : Bhattacharyya, Borthakur, Dudeja, Tobacman: Lipopolysaccharide-induced activation of NF-κB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations. in Experimental cell research 2010 (PubMed)
    Zeige alle 4 Referenzen für 658077

  3. Human Polyclonal MAP3K14 Primary Antibody für EIA, IHC (p) - ABIN360384 : Andreakos, Smith, Monaco, Brennan, Foxwell, Feldmann: Ikappa B kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction. in Blood 2003 (PubMed)
    Zeige alle 3 Referenzen für 360384

Weitere Antikörper gegen MAP3K14 Interaktionspartner

Human Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) Interaktionspartner

  1. OLFM1 (zeige OLFM1 Antikörper) is a negative regulator of non-canonical NF-kappaB (zeige NFKB1 Antikörper) signalling by interacting with and inhibiting NIK. Thus, OLFM1 (zeige OLFM1 Antikörper) may serve as a valuable biomarker and therapeutic target for colorectal cancer (CRC (zeige CALR Antikörper)) patients.

  2. The expression of OTUD7B (zeige OTUD7B Antikörper) and NIK were negatively correlated in non-small cell lung cancer tumor samples. the higher expression of NIK was related to more lymph node metastasis and later TNM (zeige ODZ1 Antikörper) stage. high OTUD7B (zeige OTUD7B Antikörper)/low NIK index can predict an good prognosis.

  3. NIK expression was significantly increased in the tumor tissue of patients with breast carcinoma, which may be an important factor that affects the prognosis of these patients.

  4. This study identified two novel independent loci (MAP3K14 and CARD9 (zeige CARD9 Antikörper)) strongly associated with joint damage in Mexican Americans and European Americans and a few shared loci showing suggestive evidence for association.

  5. The forced expression of NDRG2 (zeige NDRG2 Antikörper) in ATL cells down-regulates not only the canonical pathway by inhibiting AKT (zeige AKT1 Antikörper) signaling but also the non-canonical pathway by inducing NF-kappaB (zeige NFKB1 Antikörper)-inducing kinase (NIK) dephosphorylation via the recruitment of PP2A (zeige PPP2R4 Antikörper)

  6. NIK(+) endothelial cells may play an important role in the persistence of synovitis

  7. Data suggest microRNA302c, but not microRNA520e, promotes replication of influenza A virus H3N2 although the two microRNAs target same site of NFkappaB (zeige NFKB1 Antikörper)-inducing kinase (MAP3K14) 3prime untranslated region; studies were conducted in lung epithelial cells.

  8. TWEAK (zeige TNFSF12 Antikörper) induces noncanonical NF-kappaB (zeige NFKB1 Antikörper) signaling and signal-specific regulation of NIK mRNA expression.

  9. by demonstrating a critical role of NIK in mediating NF-kappaB (zeige NFKB1 Antikörper) activation and BAG3 (zeige BAG3 Antikörper) induction upon ST80/Bortezomib cotreatment, our study provides novel insights into mechanisms of resistance to proteotoxic stress in RMS

  10. Loss-of-function mutations in NIK can cause B-cell lymphopenia, hypogammaglobulinemia, impaired ICOSL (zeige ICOSLG Antikörper) expression, and disordered T helper cell and NK cell function.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) Interaktionspartner

  1. this study demonstrates that although NIK (zeige MAP4K4 Antikörper) is dispensable for thymocyte development, it has a cell-intrinsic role in regulating the homeostasis and function of peripheral T cells

  2. Using a novel conditional mutant of NIK (zeige MAP4K4 Antikörper), the authors could show in vivo that NIK (zeige MAP4K4 Antikörper) signaling in thymic epithelial cells is essential for the thymic hardwiring of gammadelta T cell cytokine production.

  3. NIK (zeige MAP4K4 Antikörper) not only contributes to lymphoid organogenesis, inflammation and cell survival but also to TNFR1 (zeige TNFRSF1A Antikörper)/RIP1 (zeige RALBP1 Antikörper)-dependent cell death independently of the alternative NF-kappaB (zeige NFKB1 Antikörper) pathway.

  4. This study demonstrated that NFkappaB-inducing kinase inhibits NFkappaB activity specifically in neurons of the CNS.

  5. results assign NIK (zeige MAP4K4 Antikörper)-induced alternative NF-kappaB (zeige NFKB1 Antikörper) signaling a master regulatory role in B-cells, starting from the T1 stage and also show that B-1 B cells are less dependent on this pathway, presumably owing to the existence of alternative pathways yet to be determined

  6. NIK (zeige MAP4K4 Antikörper), and thus probably the noncanonical NF-kappaB (zeige NFKB1 Antikörper) pathway, is critical to allow DCs to acquire the capacity to cross-present antigen and prime CD8 (zeige CD8A Antikörper) T cells after exposure to licensing stimuli.

  7. Deletion of NIK (zeige MAP4K4 Antikörper) in adult mice results in decreases in B cell populations in lymph nodes and spleen, similar to what is observed upon blockade of BAFF (zeige TNFSF13B Antikörper).

  8. We identify NIK (zeige MAP4K4 Antikörper) as a critical negative regulator of beta cell function, as pharmacological NIK (zeige MAP4K4 Antikörper) activation results in impaired glucose-stimulated insulin (zeige INS Antikörper) secretion in mouse and human islets.

  9. the NIK (zeige MAP4K4 Antikörper) in thymic stroma may be critically involved in the differentiation of most NKT (zeige CTSL1 Antikörper) cell subsets (although the level of NIK (zeige MAP4K4 Antikörper) dependence may vary among the subsets), and also the NIK (zeige MAP4K4 Antikörper) in NKT (zeige CTSL1 Antikörper)-alphabeta cells may be dispensable for their effector function.

  10. CHIP/TRAF3 (zeige TRAF3 Antikörper)/NIK (zeige MAP4K4 Antikörper) interactions recruit NIK (zeige MAP4K4 Antikörper) to E3 ligase complexes for ubiquitination and degradation, thus maintaining NIK (zeige MAP4K4 Antikörper) at low levels

MAP3K14 Antigen-Profil

Beschreibung des Gens

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

Alternative names and synonyms associated with MAP3K14

  • mitogen-activated protein kinase kinase kinase 14 (MAP3K14) Antikörper
  • mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) Antikörper
  • mitogen-activated protein kinase kinase kinase 14 (Map3k14) Antikörper
  • mitogen-activated protein kinase kinase kinase 14 (MAPKKK14) Antikörper
  • aly Antikörper
  • F23F1.4 Antikörper
  • F23F1_4 Antikörper
  • FLH21957 Antikörper
  • FTDCR1B Antikörper
  • HGK Antikörper
  • HS Antikörper
  • HSNIK Antikörper
  • MEKKK4 Antikörper
  • mitogen-activated protein kinase kinase kinase 14 Antikörper
  • Nik Antikörper

Bezeichner auf Proteinebene für MAP3K14

NF-kappa-beta-inducing kinase , serine/threonine protein-kinase , serine/threonine-protein kinase NIK , HPK/GCK-like kinase HGK , MAPK/ERK kinase kinase kinase 4 , MEK kinase kinase 4 , Ste20 group protein kinase HGK , hepatocyte progenitor kinase-like/germinal center kinase-like kinase , nck-interacting kinase , NF kappa B-inducing kinase , Nfkb inducing kinase , alymphoplasia , protein kinase

GENE ID SPEZIES
9020 Homo sapiens
9448 Homo sapiens
360640 Rattus norvegicus
817555 Arabidopsis thaliana
53859 Mus musculus
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