anti-ARHGEF6 (ARHGEF6) Antikörper

Auf finden Sie aktuell 36 rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6) Antikörper von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ARHGEF6 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 45 ARHGEF6 Produkte verfügbar.
1600028C08Rik, 1700038J06Rik, 4930592P22Rik, alpha-PIX, alphaPIX, Cool-2, COOL2, MRX46, PIXA
Alle Antikörper anzeigen Gen GeneID UniProt
ARHGEF6 9459 Q15052
ARHGEF6 73341 Q8K4I3
ARHGEF6 363509 Q5XXR3

Meistgesuchte Reaktivitäten zu anti-ARHGEF6 (ARHGEF6) Antikörper

anti-Human ARHGEF6 Antikörper:

anti-Mouse (Murine) ARHGEF6 Antikörper:

anti-Rat (Rattus) ARHGEF6 Antikörper:

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Weitere Antikörper gegen ARHGEF6 Interaktionspartner

Human rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6) Interaktionspartner

  1. we discuss recent findings in key physiological systems that exemplify current understanding of the function of this important regulatory complex. Further, we draw attention to gaps in crucial information that remain to be filled to allow a better understanding of the many roles of the GIT-PIX (zeige ARHGEF7 Antikörper) complex in health and disease

  2. show that ARHGEF6 is constitutively linked to GIT1, a GAP of Arf family small G proteins, and that ARHGEF6 phosphorylation enables binding of the 14-3-3 adaptor protein to the ARHGEF6/GIT1 complex

  3. The novel recycling regulator alpha-PIX and the degradation factor c-Cbl (zeige CBL Antikörper) closely cooperate in the regulation of EGFR (zeige EGFR Antikörper) trafficking.

  4. c-Cbl (zeige CBL Antikörper) negatively regulates alphaPix-mediated cell migration and invasion; the lack of c-Cbl (zeige CBL Antikörper) in C6 and A172 glioma cells is responsible for their malignant behavior

  5. results suggest that low doses of chlorambucil and very low doses of chronic oxidative stress together kill Cbl (zeige CBL Antikörper)-resistant ovarian carcinoma cells and ARHGEF6 signaling may have an instrumental role in induction of apoptosis in Cbl (zeige CBL Antikörper)(cos) cells.

  6. These findings suggest that alpha Pix plays an important role in mutant huntingtin (zeige HTT Antikörper) aggregation.

  7. The interaction of alphaPix with CagA (zeige S100A8 Antikörper) activates PAK1 (zeige PAK1 Antikörper), ERK (zeige EPHB2 Antikörper) and NF-kappaB (zeige NFKB1 Antikörper), which induces IL-8 (zeige IL8 Antikörper) expression in H. pylori-infected gastric epithelial cells.

  8. The plexin-B1 (zeige PLXNB1 Antikörper)/Rac (zeige AKT1 Antikörper) interaction inhibits PAK activation and enhances Sema4D (zeige SEMA4D Antikörper) ligand binding

  9. Expression of Cbl-b effectively blocks the ability of Cool-2 to stimulate PAK, providing an additional mechanism, aside from catalyzing receptor ubiquitination, by which Cbl-b acts as a negative regulator for signaling activities requiring PAK activation.

  10. Data suggest that Rac (zeige AKT1 Antikörper)-dependent activation of the NFkappaB (zeige NFKB1 Antikörper) pathway may be a critical element promoting thrombin (zeige F2 Antikörper)-induced tissue factor (zeige F3 Antikörper) expression and activity, and thus a prothrombotic state in pulmonary hypertension.

Mouse (Murine) rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6) Interaktionspartner

  1. this study has identified a new role for Parvin (zeige PARVA Antikörper) and alphaPix downstream of the integrin-ILK (zeige ILK Antikörper) signaling axis for mammary epithelial cell differentiation.

  2. Enforced expression of miR-135a in highly tumorigenic cancer stem cells strongly inhibited tumorigenesis by repressing the miR-135a direct target gene Arhgef6.

  3. Results indicate Arhgef6 (alphaPIX) as a regulator of thymocyte migration and subsequent arrest that is linked to positive selection.

  4. alphaPIX and GIT2 (zeige GIT2 Antikörper) are required for neuronal differentiation.

  5. suggest that imbalance in activity of different Rho GTPases may underlie altered neuronal connectivity and impaired synaptic function and cognition in alphaPix/Arhgef6 knockout mice

  6. The mouse Arhgef6 gene: cDNA sequence, expression analysis, and X chromosome assignment.

  7. ARHGEF6 is localized in dendritic spines where it contributes to regulate dendritic spine morphogenesis.

  8. These results reveal specific roles for alphaPIX in the immune system and suggest that redundancy with betaPIX (zeige ARHGEF7 Antikörper) precludes a more severe immune phenotype.

ARHGEF6 Antigen-Profil

Beschreibung des Gens

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.

Alternative names and synonyms associated with ARHGEF6

  • Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) Antikörper
  • Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (Arhgef6) Antikörper
  • 1600028C08Rik Antikörper
  • 1700038J06Rik Antikörper
  • 4930592P22Rik Antikörper
  • alpha-PIX Antikörper
  • alphaPIX Antikörper
  • Cool-2 Antikörper
  • COOL2 Antikörper
  • MRX46 Antikörper
  • PIXA Antikörper

Bezeichner auf Proteinebene für ARHGEF6

PAK-interacting exchange factor alpha , PAK-interacting exchange factor, alpha , Rac/Cdc42 guanine exchange factor (GEF) 6 , rac/Cdc42 guanine nucleotide exchange factor 6 , rho guanine nucleotide exchange factor 6 , alpha PIX Rho GTPase guanine nucleotide exchange factor , rac/cdc42 guanine nucleotide exchange factor 6

9459 Homo sapiens
73341 Mus musculus
363509 Rattus norvegicus
422247 Gallus gallus
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