Urotensin 2 Proteine (UTS2)

Auf www.antikoerper-online.de finden Sie aktuell 4 Urotensin 2 (UTS2) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Urotensin 2 Antikörper (91) und Urotensin 2 Kits (41) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 166 Urotensin 2 Produkte verfügbar.
prepro-UII, PRO1068, U-II, Ucn2, UII, UTS2
alle Proteine anzeigen Gen GeneID UniProt
UTS2 10911 O95399
Ratte UTS2 UTS2 29180 Q9QZQ4
Maus UTS2 UTS2 24111 Q9QZQ3

Urotensin 2 Proteine (UTS2) nach Spezies

Weitere Proteine zu Urotensin 2 Interaktionspartnern

Human Urotensin 2 (UTS2) Interaktionspartner

  1. UII/GPR14 signaling was involved in the DSS (zeige NR0B1 Proteine)-induced colonic inflammation and its inhibition may serve as a potential therapeutic target, which may be associated with the NF-kappaB (zeige NFKB1 Proteine) signaling pathway.

  2. Ser89Asn polymorphisms of the UTS2 gene are significantly associated with atrial fibrillation in the Chinese population. Additionally, we demonstrated that genotype Met21Met may have a potential beneficial role in atrial fibrillation.

  3. Serum urotensin II levels were significantly lower in hemodialysis patients compared to healthy subjects.

  4. expression of UII is associated with ERS in patients with SPE. Our results indicate that UII may trigger ERS in placental trophoblastic cells in patients with preeclampsia.

  5. Our study suggests that U-II may play a role in migraine pathogenesis; also Thr21Met polymorphism was associated with the risk of migraine disease.

  6. Used transgenic rabbits as a model to study macrophage-specific expressing human UII (hUII) and studied the role of autocrine UII in the development of atherosclerosis.

  7. Urotensin II-increased reactive oxygen species production via the NADPH oxidase (zeige NOX1 Proteine) pathway is partially associated with activation of the PI3K (zeige PIK3CA Proteine)/Akt (zeige AKT1 Proteine) and ERK (zeige EPHB2 Proteine) cascades

  8. provide evidence that, in glioma cells, homogeneous concentration of UII allowed translocation of Galpha13 (zeige GNA13 Proteine) to the UT receptor at the plasma membrane and increased actin stress fibers, lamellipodia formation and vinculin (zeige VCL Proteine)-stained focal adhesions

  9. enzyme-linked immunosorbent assay (ELISA) and restriction fragment length polymorphism analysis were used to evaluate plasma levels of urotensin-II and Thr21Met and Ser89Asn polymorphisms of UTS2 gene in breast cancer patients.

  10. Urotensin II can induce the proliferation of BEL (zeige LHX2 Proteine)-7402 cells via the urotensin receptor mediated PKC (zeige PRRT2 Proteine)/ERK/p38 MAPK (zeige MAPK1 Proteine) signaling pathways.

Mouse (Murine) Urotensin 2 (UTS2) Interaktionspartner

  1. Urotensin II plays a role in the pathogenesis and priming of acute liver failure by triggering an inflammatory cascade and driving the early release of TNF-alpha (zeige TNF Proteine) and Il1beta (zeige IL1B Proteine).

  2. UII/UTR system plays a role in lipopolysaccharide (LPS (zeige TLR4 Proteine))/D-galactosamine (GalN (zeige GAL Proteine))-induced acute liver failure.

  3. Data suggest that aortic urotensin II (UII) is increased in diabetes-associated atherosclerosis in humans and mice; diabetes-associated plaque development is attenuated by UII/UII receptor antagonism in in vitro (human) and in vivo (mouse) settings.

  4. It is believed that U-II is an important mediator in Systemic sclerosis.

  5. role of urotensin II gene deletion in atherosclerosis and suggest that the use of pharmaceutical agents aimed at blocking the urotensin II pathway may provide a novel approach in the treatment of atherosclerosis.

  6. mouse UII is expressed in a subpopulation of motoneurons in the spinal cord

  7. In the CNS UII mRNAs are expressed in brainstem and spinal motoneurons, also expressed in the medial vestibular nucleus, locus coeruleus and the ventral medulla.

  8. increased plasma urotensin II level stimulates oxidized low-density lipoprotein and reactive oxygen species production and macrophage foam cell formation

  9. Elevated expression of Uts2 in skeletal muscle of diabetic mouse is reported.

Urotensin 2 (UTS2) Protein Überblick

Protein Überblick

This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene.

Alternative names and synonyms associated with Urotensin 2 (UTS2)

  • urotensin 2 (UTS2)
  • urotensin 2 (uts2)
  • urotensin 2 (Uts2)
  • prepro-UII Protein
  • PRO1068 Protein
  • U-II Protein
  • Ucn2 Protein
  • UII Protein
  • UTS2 Protein

Bezeichner auf Proteinebene für Urotensin 2 Proteine (UTS2)

urotensin 2 , prepro U-II , urotensin II , urotensin-2 , U-II , UII , urocortin 2 , urotensin-II

746007 Pan troglodytes
100379687 Xenopus (Silurana) tropicalis
10911 Homo sapiens
29180 Rattus norvegicus
24111 Mus musculus
397268 Sus scrofa
574246 Macaca mulatta
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