Chromogranin A Proteine (CHGA)

Chromogranin A Proteine (CHGA)
Auf finden Sie aktuell 31 Chromogranin A (CHGA) Proteine von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Chromogranin A Antikörper (707) und Chromogranin A Kits (70) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 849 Chromogranin A Produkte verfügbar.
cgA, CHGA, ChrA, fj05f09, si:dkey-177p2.2, wu:fj05f09, zgc:56075, zgc:101749
alle Proteine anzeigen Gen GeneID UniProt
CHGA 12652 P26339
CHGA 1113 P10645
CHGA 24258  

Weitere Synonyme anzeigen

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Am meisten referenzierte Chromogranin A Proteine

  1. Human CHGA Protein expressed in Escherichia coli (E. coli) - ABIN667739 : Montero-Hadjadje, Elias, Chevalier, Benard, Tanguy, Turquier, Galas, Yon, Malagon, Driouich, Gasman, Anouar: Chromogranin A promotes peptide hormone sorting to mobile granules in constitutively and regulated secreting cells: role of conserved N- and C-terminal peptides. in The Journal of biological chemistry 2009 (PubMed)
    Zeige alle 2 Referenzen für 667739

Weitere Proteine zu Chromogranin A Interaktionspartnern

Zebrafish Chromogranin A (CHGA) Interaktionspartner

  1. Study indicates that chga may play an important role in nervous system development during the early embryonic stages.

Mouse (Murine) Chromogranin A (CHGA) Interaktionspartner

  1. Increased myocardial CgA (zeige CGA Proteine) glycosylation and impaired CgA (zeige CGA Proteine) processing to catestatin in heart failure be considered detrimental because CST (zeige CORT Proteine) reduces diastolic Ca2 (zeige CA2 Proteine)+ leak via direct CaMKIIdelta inhibition.

  2. performance of CgA (zeige CGA Proteine)-deficient Chga-KO mice in treadmill exercise was impaired. CgA (zeige CGA Proteine) deficiency renders the muscle energy deficient, impairs performance in treadmill exercise and prevents regeneration after exercise-induced tissue damage.

  3. dilated mitochondrial cristae, endoplasmic reticulum and Golgi complex, as well as increased synaptic mitochondria, synaptic vesicles and glycogen (zeige GYS1 Proteine) granules in Chga-knockout mice compared to WT mice.

  4. the presence of ChgA and subsequent activation of ChgA-reactive T cells are essential for the initiation and development of autoimmune diabetes in NOD mice.

  5. Studied leptin (zeige LEP Proteine) and CST (zeige CORT Proteine) modulation of SGLT1 (zeige SLC5A1 Proteine) expression in hyperleptinemic type 2 diabetic mice.

  6. N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes.

  7. Data indicate that T-cell receptors that react to chromogranin A (ChgA) and islet amyloid polypeptide (zeige IAPP Proteine) precursor (IAPP (zeige IAPP Proteine)) autoantigens were impaired when the thymic stromal cells lacked thymus-specific serine protease (TSSP (zeige PRSS16 Proteine)).

  8. the important roles of CgA and CgB in glucose and cardiovascular homeostasis. This study also unveils the existence of direct implications of Cgs in the control of behaviour and mood.

  9. Chromogranin A (10-19) and chromogranin A (43-52) were identified as antigens for autoreactive CD8 (zeige CD8A Proteine)(+) T cells in NOD.beta2m(null).HHD mice.

  10. Report QT/heart rate variability in a genomically "humanized" chromogranin a monogenic mouse model with hyperadrenergic hypertension.

Human Chromogranin A (CHGA) Interaktionspartner

  1. Plasma catestatin was associated with coronary collateral developments, suggesting a useful biomarker for coronary collateral development and potential target for therapeutic angiogenesis in patients with coronary artery chronic total occlusions (CTO (zeige ATP6V0D1 Proteine)).

  2. Increased myocardial CgA (zeige CGA Proteine) glycosylation and impaired CgA (zeige CGA Proteine) processing to catestatin in heart failure be considered detrimental because CST (zeige GAL3ST1 Proteine) reduces diastolic Ca2 (zeige CA2 Proteine)+ leak via direct CaMKIIdelta inhibition.

  3. Data suggest pancreastatin, a 49 residue post-translational fragment of chromogranin A, as a routinely tested biomarker in neuroendocrine tumors (NETs) and in particular small bowel NET.

  4. Data indicate that measurement of chromogranin A (CgA) alone is sufficient in the management of patients with neuroendocrine tumours (NETs) and that routine additional measurement of chromogranin B (CgB (zeige CHGB Proteine)) provides little added value.

  5. Data show that chrysin suppressed cell proliferation and reducing expression of achaete-scute complex-like 1 (ASCL1 (zeige ASCL1 Proteine)) and the neuroendocrine biomarker chromogranin A (CgA).

  6. In a Japanese population, the Ser (zeige SIGLEC1 Proteine)-364 allele was associated with elevated systolic blood pressure and pulse pressure, consistent with increased arterial stiffness.

  7. ChrA levels were not effective in predicting outcomes or detecting recurrences of Merkel cell carcinoma.

  8. Decreased CSF (zeige CSF2 Proteine) levels of chromogranin A were found in Parkinson disease patients with orthostatic hypotension.

  9. In both mice and men the Gly364Ser polymorphism conferred metabolic traits such as elevated HDL (zeige HSD11B1 Proteine) and lowered norepinephrine levels; it was associated with superior baroreflex function and therefore better response to stress.

  10. In patients with resected pancreatic neuroendocrine tumors, an elevated preoperative CgA (zeige CGA Proteine) level was negatively associated with disease-free survival and overall survival.

Pig (Porcine) Chromogranin A (CHGA) Interaktionspartner

  1. High pancreastatin levels are significantly associated with neuroendocrine tumors.

  2. No circadian pattern was detected for salivary CgA in either spring or autumn, and there were no significant effects of gender or age. However, mean salivary CgA concentrations were significantly higher in the pigs sampled in autumn, compared to spring.

  3. expression and localization of chromogranin A (CgA), chromogranin B (CgB (zeige CHGB Proteine)), synaptophysin (zeige SYP Proteine), and insulin (zeige INS Proteine) were ultrastructurally studied with the immunogold technique in porcine and human pancreatic islet neuroendocrine cells

Cow (Bovine) Chromogranin A (CHGA) Interaktionspartner

  1. Vasoconstriction-Inhibiting Factor (VIF (zeige BTG1 Proteine)), a degradation product of chromogranin A, is a vasoregulatory peptide that modulates the vasoconstrictive effects of angiotensin II by acting on the angiotensin II type 2 receptor (zeige AGTR2 Proteine).

  2. chromogranin A has a role in the IP(3)-mediated Ca(2 (zeige CA2 Proteine)+) release mechanism of secretory granules

  3. chromogranin A has a specific site in the N-terminal domain that can bind membrane lipids from different species

  4. role of coupling with the inositol 1,4,5-trisphosphate receptor/Ca2 (zeige CA2 Proteine)+ channel (InsP3R (zeige ITPR1 Proteine))in the Ca2 (zeige CA2 Proteine)+-dependent ciliary movement

  5. involvement of CGA (zeige CGA Proteine) with other components of the senile plaque

  6. significant species differences in vasoactivity of the N-terminal domain of ChgA

  7. determination of the subcellular distribution of chromogranins A and B in chromaffin cells; results suggest that chromogranins are at the center of intracellular Ca(2 (zeige CA2 Proteine)+) homeostasis in secretory cells

Chromogranin A (CHGA) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides\; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.

Alternative names and synonyms associated with Chromogranin A (CHGA)

  • chromogranin A (chga)
  • chromogranin A (CHGA)
  • chromogranin A (Chga)
  • chromogranin A (parathyroid secretory protein 1) (CHGA)
  • chromogranin A (parathyroid secretory protein 1) (Chga)
  • cgA Protein
  • CHGA Protein
  • ChrA Protein
  • fj05f09 Protein
  • si:dkey-177p2.2 Protein
  • wu:fj05f09 Protein
  • zgc:56075 Protein
  • zgc:101749 Protein

Bezeichner auf Proteinebene für Chromogranin A Proteine (CHGA)

chromogranin-A , chromogranin A , cgA , SP-I , betagranin (N-terminal fragment of chromogranin A) , parathyroid secretory protein 1 , pituitary secretory protein I , pancreastatin

450039 Danio rerio
574388 Macaca mulatta
12652 Mus musculus
1113 Homo sapiens
397540 Sus scrofa
24258 Rattus norvegicus
607527 Canis lupus familiaris
281070 Bos taurus
100717887 Cavia porcellus
100033828 Equus caballus
423420 Gallus gallus
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