alpha Adducin Proteine (ADD1)

Auf finden Sie aktuell 6 Adducin 1 (Alpha) (ADD1) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen alpha Adducin Antikörper (190) und alpha Adducin Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 211 alpha Adducin Produkte verfügbar.
ADD-1, ADD1, add1-a, add2, ADDA, AI256389, alpha-adducin, bHLHd1, bZ1H20.1, cb787, D630008H06, SREBP-1, SREBP-1a, SREBP-1c, Srebp1, SREBP1c, zgc:158352
alle Proteine anzeigen Gen GeneID UniProt
ADD1 118 P35611
ADD1 11518 Q9QYC0
Ratte ADD1 ADD1 24170 Q63028

alpha Adducin Proteine (ADD1) nach Spezies

Weitere Proteine zu alpha Adducin Interaktionspartnern

Human Adducin 1 (Alpha) (ADD1) Interaktionspartner

  1. ZNF322A (zeige ZNF322A Proteine) overexpression transcriptionally dysregulates genes involved in cell growth and motility therefore contributes to lung tumorigenesis and poor prognosis

  2. ADD1 rs4963 polymorphism showed an increased hypertension risk.

  3. This indicates that ADD1 G460W polymorphism could be an important factor in the pathophysiology of tinnitus.

  4. Study shows that ADD1-rs4963 conferred susceptibility to colorectal cancer (CRC (zeige CALR Proteine)) suggesting an association between ADD1 and CRC (zeige CALR Proteine) risk.

  5. The T allele of ADD1 is associated with essential hypertension in Asians.

  6. study of potential effects of interaction between DNA methylation (zeige HELLS Proteine) of ADD1 promoter and ADD1 tagSNPs and environmental factors on essential hypertension (EH); results indicate ADD1 SNP rs4961 has a protective role in development of EH; interactions between alcohol consumption and DNA methylation (zeige HELLS Proteine) of ADD1 gene promoter have a significant role in modifying EH susceptibility

  7. There were significant differences between the control group and pediatric hypertensive group in terms of ACE (zeige ACE Proteine) I/D (P<0.05) and AGT (zeige AGXT Proteine) M235T (P<0.05) polymorphisms, but there were no differences in ADD Gly460Trp (P>0.05) polymorphism.

  8. A significant association was found between ADD1 gene G614T polymorphism and essential hypertension in Chinese patients. Further studies need to be done to confirm these findings in a large sample.

  9. When alpha-adducin complexes with sodium potassium ATPase in astrocytes, non-cell autonomous neurodegeneration is triggered.

  10. Phosphorylation of ADD1 at Ser12 and Ser355 by cyclin-dependent kinase 1 enables ADD1 to bind to myosin-X (Myo10).

Mouse (Murine) Adducin 1 (Alpha) (ADD1) Interaktionspartner

  1. suggesting a specific effect of sterol regulatory element binding protein (zeige CNBP Proteine)-1c on neurosteroidogenesis

  2. Transforming growth factor-beta activated kinase 1 (TAK1 (zeige MAP3K7 Proteine)) regulation of sterol-regulatory element-binding proteins (SREBPs) critically contributes to the maintenance of liver homeostasis to prevent steatosis, which is a potentially important mechanism to prevent hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) development.

  3. miR (zeige MLXIP Proteine)-185 negatively regulates the differentiation of 3T3-L1 cells by targeting SREBP-1 (zeige SREBF1 Proteine)

  4. SREBP1 (zeige SREBF1 Proteine) pathway plays an important role in hepatocellular carcinoma pathogenesis.

  5. In hepatocytes, E4BP4 (zeige NFIL3 Proteine) interacts with nuclear SREBP-1c (zeige SREBF1 Proteine) to preserve its acetylation, and subsequently protects it from ubiquitination-dependent degradation

  6. SREBP1 (zeige SREBF1 Proteine) also contributes to the resolution phase of TLR4 (zeige TLR4 Proteine)-induced gene activation by reprogramming macrophage lipid metabolism.

  7. 27OH is not an important regulator of Srebp- or LXR regulated genes under basal conditions in mouse liver

  8. Collectively, these findings demonstrate that LXRalpha (zeige NR1H3 Proteine) activation induces 17beta-HSD13 expression in a SREBP-1c (zeige SREBF1 Proteine)-dependent manner.

  9. These results demonstrate that HDAC3 and SCAP control symbiotic pathways of liver lipid metabolism that are critical for suppression of lipotoxicity.

  10. data indicate that ATF4 (zeige ATF4 Proteine) regulates SREBP1c (zeige SREBF1 Proteine) expression to control fatty acids synthesis

alpha Adducin (ADD1) Protein Überblick

Protein Überblick

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms\; however, not all variants have been fully described.

Alternative names and synonyms associated with alpha Adducin (ADD1)

  • adducin 1 (alpha) (ADD1)
  • adducin 1 (alpha) (add1-a)
  • adducin 1 (alpha) (add1)
  • adducin 1 (alpha) (LOC100220908)
  • adducin 1 (alpha) (LOC100351048)
  • adducin 1 (alpha) (Add1)
  • sterol regulatory element binding transcription factor 1 (Srebf1)
  • ADD-1 Protein
  • ADD1 Protein
  • add1-a Protein
  • add2 Protein
  • ADDA Protein
  • AI256389 Protein
  • alpha-adducin Protein
  • bHLHd1 Protein
  • bZ1H20.1 Protein
  • cb787 Protein
  • D630008H06 Protein
  • SREBP-1 Protein
  • SREBP-1a Protein
  • SREBP-1c Protein
  • Srebp1 Protein
  • SREBP1c Protein
  • zgc:158352 Protein

Bezeichner auf Proteinebene für Adducin 1 (Alpha) Proteine (ADD1)

adducin 1 (alpha) , alpha-adducin-like , adducin 2 (beta) , alpha-adducin , erythrocyte adducin alpha subunit , erythrocyte adducin subunit alpha , alpha-ADD , adipocyte determination- and differentiation-dependent factor 1 , sterol regulatory element-binding protein 1

100051451 Equus caballus
100401343 Callithrix jacchus
100483493 Ailuropoda melanoleuca
394387 Xenopus laevis
448173 Xenopus (Silurana) tropicalis
700805 Macaca mulatta
740376 Pan troglodytes
100015485 Monodelphis domestica
100220908 Taeniopygia guttata
100351048 Oryctolagus cuniculus
100541144 Meleagris gallopavo
100564853 Anolis carolinensis
100590491 Nomascus leucogenys
118 Homo sapiens
11518 Mus musculus
24170 Rattus norvegicus
555511 Danio rerio
422882 Gallus gallus
488796 Canis lupus familiaris
100517353 Sus scrofa
507193 Bos taurus
100172752 Pongo abelii
20787 Mus musculus
78968 Rattus norvegicus
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