anti-RGS6 (RGS6) Antikörper

anti-Regulator of G-Protein Signaling 6 Antikörper (RGS6)
Auf finden Sie aktuell 28 Regulator of G-Protein Signaling 6 (RGS6) Antikörper von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RGS6 Proteine (6) und RGS6 Kits (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 44 RGS6 Produkte verfügbar.
DKFZp459O0734, GAP, hm:zeh0300, RGS6, si:ch211-268e23.2

Meistgesuchte Reaktivitäten zu anti-RGS6 (RGS6) Antikörper

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anti-Human RGS6 Antikörper:

anti-Mouse (Murine) RGS6 Antikörper:

anti-Rat (Rattus) RGS6 Antikörper:

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Am meisten referenzierte anti-RGS6 Antikörper

  1. Human Polyclonal RGS6 Primary Antibody für WB - ABIN2778234 : Gu, Wu, Dong, Romeo, Lin, Gutkind, Berman: A nonsynonymous single-nucleotide polymorphism in the PDZ-Rho guanine nucleotide exchange factor (Ser1416Gly) modulates the risk of lung cancer in Mexican Americans. in Cancer 2006 (PubMed)

  2. Human Polyclonal RGS6 Primary Antibody für WB - ABIN252606 : Chen, Shim, Morhardt, Dallman, Krahn, McWhinney, Rao, Gold, Chen: Functional redundancy of R7 RGS proteins in ON-bipolar cell dendrites. in Investigative ophthalmology & visual science 2010 (PubMed)

  3. Cow (Bovine) Polyclonal RGS6 Primary Antibody für IHC, WB - ABIN2778235 : Liu, Fisher: RGS6 interacts with DMAP1 and DNMT1 and inhibits DMAP1 transcriptional repressor activity. in The Journal of biological chemistry 2004 (PubMed)

Weitere Antikörper gegen RGS6 Interaktionspartner

Human Regulator of G-Protein Signaling 6 (RGS6) Interaktionspartner

  1. Data support the notion that the Galpha (zeige SUCLG1 Antikörper), but not Gbetagamma, arm of the Gi/o signalling is involved in TRPC4 (zeige TRPC4 Antikörper) activation and unveil new roles for RGS (zeige PITX2 Antikörper) and RGS6 in fine-tuning TRPC4 (zeige TRPC4 Antikörper) activities.

  2. No significant association between SNPs of RGS6 and central adiposity has been found.

  3. reduced RGS6 expression is associated with poor survival in colorectal cancer patients, suggesting that RGS6 expression may serve as an important prognostic marker

  4. these date demonstrate that RGS6 decreases in tumor tissue and may serve as a novel biomarker for outcomes in pancreatic cancer patients and be a potential therapeutic target potential therapeutic target.

  5. we found a novel mutation in RGS6, the splice-acceptor variant c.1369-1G>C that was not previously reported in congenital cataract phenotypes.

  6. genetic association studies in Hispanic-American families in Texas and Colorado: SNP in RGS6 are associated with high dietary fat intake, food preferences, and adiposity/obesity phenotype

  7. RGS6-induced apoptosis in both breast cancer cells and mouse embryonic fibroblasts does not require its GAP activity toward G proteins

  8. interacts with SCG10 (zeige STMN2 Antikörper) and promotes neuronal differentiation; role of the G gamma subunit-like (GGL (zeige GGT5 Antikörper)) domain of this protein

  9. Role of the RGS (zeige PITX2 Antikörper) domain in stress-induced trafficking of RGS6 protein

  10. RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL (zeige GGT5 Antikörper)) domain in subcellular localization of RGS6 splice variants

Mouse (Murine) Regulator of G-Protein Signaling 6 (RGS6) Interaktionspartner

  1. The genetic loss of Rgs6 is associated with three phenotypes each individually associated with midbrain dopaminergic neuron neuron degeneration.

  2. propose that inhibition of RGS6 might represent a viable means to reduce alcohol cravings and withdrawal in human patients, while simultaneously protecting the heart and liver from further damage upon relapse

  3. RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60 (zeige KAT5 Antikörper)-mediated Dnmt1 (zeige DNMT1 Antikörper) degradation and promoting apoptosis

  4. Data indicate taht m2R-RGS6-IKACh pathway sets heart rate variability independently from the autonomic input.

  5. Data indicate that genetic ablation of RGS6 expression resulted in anxiolytic and antidepressant behavior by enhancing signaling through the 5-HT1A receptor (zeige CC2D1A Antikörper)-adenylyl cyclase (AC) axis.

  6. RGS6-Gbeta5 (zeige GNB5 Antikörper), but not RGS4 (zeige RGS4 Antikörper), is the primary RGS (zeige PITX2 Antikörper) modulator of parasympathetic HR regulation and SAN M2R-IKACh signaling in mice.

  7. Spontaneous tumor formation was also seen in old female RGS6(-/-) but not in wild-type mice.

  8. results identify RGS6 as an essential mediator of the pathogenic responses to doxorubicin in heart, and they argue that RGS6 inhibition offers a rational means to circumvent doxorubicin cardiotoxicity in human patients with cancer

  9. establish RGS6 as a key component of GABA(B)R signaling

  10. Regulator of G-protein signaling 6 (RGS6) is a previously unrecognized, but essential, negative regulator of parasympathetic activation in heart.

RGS6 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.

Alternative names and synonyms associated with RGS6

  • regulator of G-protein signaling 6 (RGS6) Antikörper
  • regulator of G-protein signaling 6 (Rgs6) Antikörper
  • regulator of G-protein signaling 6 (rgs6) Antikörper
  • regulator of G-protein signalling 6 (rgs6) Antikörper
  • DKFZp459O0734 Antikörper
  • GAP Antikörper
  • hm:zeh0300 Antikörper
  • RGS6 Antikörper
  • si:ch211-268e23.2 Antikörper

Bezeichner auf Proteinebene für RGS6

regulator of G-protein signaling 6 , regulator of G-protein signalling 6 , regulator of G-protein signaling 6-like , GTPase activating protein , H_DJ1108A12.1 , S914 , WUGSC:H_DJ0283M22.1 , WUGSC:H_DJ1108A12.1

453009 Pan troglodytes
517545 Bos taurus
694620 Macaca mulatta
100024815 Monodelphis domestica
100055109 Equus caballus
100172360 Pongo abelii
100387876 Callithrix jacchus
100549212 Meleagris gallopavo
100579925 Nomascus leucogenys
9628 Homo sapiens
50779 Mus musculus
54295 Rattus norvegicus
734690 Xenopus laevis
395618 Gallus gallus
562667 Danio rerio
480380 Canis lupus familiaris
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