PKC eta Proteine (PRKCH)

Protein Kinase C, eta Proteine (PRKCH)
Auf finden Sie aktuell 13 Protein Kinase C, eta (PRKCH) Proteine von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PKC eta Antikörper (102) und PKC eta Kits (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 139 PKC eta Produkte verfügbar.
nPKC-eta, pkc-eta, PKC-L, Pkch, PKCL, prkch, PRKCL, si:ch211-212g7.5, zgc:172124
alle Proteine anzeigen Gen GeneID UniProt
PRKCH 5583 P24723
PRKCH 18755 P23298
PRKCH 81749 Q64617

Weitere Synonyme anzeigen

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Weitere Proteine zu PKC eta Interaktionspartnern

Human Protein Kinase C, eta (PRKCH) Interaktionspartner

  1. PRKCH is highly expressed in hematopoietic stem cell (HSC (zeige FUT1 Proteine)) and is necessary for optimal HSC (zeige FUT1 Proteine) function.

  2. The association between PRKCH 1425G/A and lacunar infarction was independent of traditional stroke risk factors

  3. Data suggest that targeted manipulation of protein kinase C isoforms PKCalpha (zeige PKCa Proteine), PKCbeta, and PKCeta might be beneficial in certain proteinuric kidney diseases with altered transient receptor potential cation channel subfamily C member 6 (zeige TRPC6 Proteine) protein (TRPC6 (zeige TRPC6 Proteine)) functions.

  4. variant genotypes of PRKCH 1425G/A are an independent prognostic factor for ischemic stroke in the final multivariate Cox (zeige COX8A Proteine) regression model

  5. Meta-analysis indicated that the 1425G/A SNP in PRKCH may contribute to susceptibility of stroke, especially for ischemic stroke.

  6. PKCeta promotes senescence through its ability to upregulate the expression of the cell cycle inhibitors p21Cip1 (zeige CDKN1A Proteine) and p27Kip1 (zeige CDKN1B Proteine) and enhance transcription and secretion of IL-6 (zeige IL6 Proteine).

  7. The 1425G/A polymorphism in PRKCH is not a significant predictor of stroke recurrence in patients with acute ischemic stroke during a 2-year follow-up period.

  8. PKC-eta associates with NHE3 (zeige SLC9A3 Proteine) and gamma tubulin (zeige TUBG1 Proteine) to promote the cell polarity during migration.

  9. the PKC family genes may play a role in the pathogenesis of MS relapse through modulating the association between 25(OH)D and relapse.

  10. Upregulation of PKCeta contributes to breast cancer cell growth and targeting either PKCepsilon (zeige PRKCE Proteine) or PDK1 (zeige PDK1 Proteine) triggers PKCeta downregulation

Mouse (Murine) Protein Kinase C, eta (PRKCH) Interaktionspartner

  1. genetic deficiency results in defective suppressive activity of T reg (zeige KCNH2 Proteine) cells

  2. data suggest that PKCeta shares some redundant roles with PKCtheta (zeige PRKCQ Proteine); in T cell biology and also performs nonredundant functions that are required for T cell homeostasis and activation

  3. Protein kinase C eta promotes a proliferation to differentiation switch in keratinocytes via upregulation of p27Kip1 (zeige CDKN1B Proteine) mRNA through suppression of JNK/c-Jun signaling under stress conditions.

  4. these results establish a previously uncharacterized role forPKC-epsilon, PKC-eta, PKC-theta (zeige PRKCQ Proteine) in T cell polarity.

  5. ATP1A1 (zeige ATP1A1 Proteine) interaction with PKCeta and occludin (zeige OCLN Proteine) was involved in the integrity of the blood-labyrinth-barrier

  6. PKC-eta/Fyn (zeige FYN Proteine)-dependent pathway leading to keratinocyte growth arrest and differentiation

  7. The expression of specific PKC isotypes was significantly changed as embryonic stem cells differentiated into cardiomyocytes.

  8. Parvovirus infection was found to result in activation of both PDK1 (zeige PDPK1 Proteine) and PKCeta, as evidenced by changes in their subcellular distribution and overall (auto)phosphorylation.

  9. directs the induction of IRF-4 (zeige IRF4 Proteine) expression downstream of BLNK (zeige BLNK Proteine) in the pre-BCR (zeige BCR Proteine) signaling pathway promoting kappa gene rearrangement

  10. Translational regulation could provide an additional level for controlling the expression of PKC family members.

PKC eta (PRKCH) Protein Überblick

Protein Überblick

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.

Alternative names and synonyms associated with PKC eta (PRKCH)

  • protein kinase C, eta (prkch)
  • protein kinase C, eta (PRKCH)
  • protein kinase C, eta, b (prkchb)
  • protein kinase C, eta, a (prkcha)
  • protein kinase C, eta (Prkch)
  • nPKC-eta Protein
  • pkc-eta Protein
  • PKC-L Protein
  • Pkch Protein
  • PKCL Protein
  • prkch Protein
  • PRKCL Protein
  • si:ch211-212g7.5 Protein
  • zgc:172124 Protein

Bezeichner auf Proteinebene für Protein Kinase C, eta Proteine (PRKCH)

protein kinase C, eta , protein kinase C eta type , protein kinase C eta type-like , PKC-L , nPKC-eta , protein kinase C-eta

444221 Xenopus laevis
490722 Canis lupus familiaris
556591 Danio rerio
746068 Pan troglodytes
100051560 Equus caballus
100144561 Danio rerio
100151731 Xenopus (Silurana) tropicalis
100410970 Callithrix jacchus
100474521 Ailuropoda melanoleuca
100545425 Meleagris gallopavo
100586510 Nomascus leucogenys
5583 Homo sapiens
18755 Mus musculus
81749 Rattus norvegicus
423518 Gallus gallus
100344184 Oryctolagus cuniculus
518542 Bos taurus
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