Paraoxonase 3 Proteine (PON3)

Auf finden Sie aktuell 6 Paraoxonase 3 (PON3) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Paraoxonase 3 Antikörper (72) und Paraoxonase 3 Kits (19) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 104 Paraoxonase 3 Produkte verfügbar.
2810004E20, AI786302
alle Proteine anzeigen Gen GeneID UniProt
PON3 5446 Q15166
PON3 269823 Q62087
Ratte PON3 PON3 312086 Q68FP2

Paraoxonase 3 Proteine (PON3) nach Spezies

Weitere Proteine zu Paraoxonase 3 Interaktionspartnern

Cow (Bovine) Paraoxonase 3 (PON3) Interaktionspartner

  1. The aim of this study was to evaluate expression of the natural anti-oxidants paraoxonase (PON) 1 (zeige PON1 Proteine), 2 and 3 in granulosa cells and PON1 (zeige PON1 Proteine) activity in follicular fluid and plasma of dairy cows.

Human Paraoxonase 3 (PON3) Interaktionspartner

  1. Data suggest that paraoxonases (PON1 (zeige PON1 Proteine), PON2 (zeige PON2 Proteine), PON3) play roles in innate immunity, inflammatory response, and protection against oxidative stress; these factors are associated with the body's response to infectious diseases; low serum PON1 (zeige PON1 Proteine) activities are associated with poor survival in patients with severe sepsis. [REVIEW]

  2. Data show that the mRNA levels of both paraoxonases PON2 (zeige PON2 Proteine) and PON3 were significantly upregulated whereas PON1 (zeige PON1 Proteine)'s mRNA was absent in transgenic mouse hearts.

  3. Although inappropriate promoter methylation was not invariantly associated with reduced transcript expression, a significant association was apparent for the ARHGEF4 (zeige ARHGEF4 Proteine), PON3, STAT5a (zeige STAT5A Proteine), and VAX2 (zeige VAX2 Proteine) gene transcripts (P<0.05). Herein, we present the first genome-wide DNA methylation (zeige HELLS Proteine) analysis in a unique HG-NMIBC cohort, showing extensive and discrete methylation changes relative to normal bladder and low-intermediate-grade tumor

  4. Low PON3 expression is associated with hepatocellular carcinoma progression.

  5. This study showed that the PI3K (zeige PIK3CA Proteine)/Akt (zeige AKT1 Proteine) pathway is up-regulated by the expression of PON3 in oral squamous cell carcinoma by AP-1 (zeige FOSB Proteine).

  6. Studies indicate that three paraoxonases PON1 (zeige PON1 Proteine), PON2 (zeige PON2 Proteine), and PON3 genes are clustered on chromosome 7, and that PONs possess numerous atheroprotective properties.

  7. PON3 SNP rs13226149 was associated with intracerebral hemorrhage in log-additive and dominant models. The A allele of rs13226149 contributed to the decreased risk of ICH (zeige COL4a2 Proteine). SNP rs1053275 was not associated with ICH (zeige COL4a2 Proteine).

  8. Data suggest cigarette smoke leads to inhibition of hydrolytic activity of paraoxonase isoenzymes (PON1 (zeige PON1 Proteine), PON2 (zeige PON2 Proteine), PON3) by modification of thiol groups, by interactions with free radicals/heavy metals, or by decreasing HDL (zeige HSD11B1 Proteine) level in blood. [REVIEW]

  9. Interaction of PON-3 and PON-1 (zeige PON1 Proteine) and HDL (zeige HSD11B1 Proteine) are associated with the presence and severity of coronary artery disease in type 2 diabetes mellitus patients.

  10. PON3 in HDL (zeige HSD11B1 Proteine) may be an important protein in preventing atherosclerosis.

Mouse (Murine) Paraoxonase 3 (PON3) Interaktionspartner

  1. study suggests a role for PON3 in the metabolism of lipid and bile acid as well as protection against atherosclerosis, gallstone disease, and obesity

  2. PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death.

  3. investigation of effect of knockout of Pon3 in embryo: Data suggest that Pon3-/- mice exhibit increased early embryonic and neonatal mortality.

  4. mouse Pon3 is expressed in a wide range of tissues, and that its expression is temporally controlled

  5. PON3 proteins were present in the vast majority of tissues investigated. mRNA for these proteins was also expressed in most of these tissues suggesting local production and the ability to respond in situ to inflammatory stimuli.

  6. The anti-atherogenic biological activities were studied in vitro using serum or cell cultures, and also in vivo, using PON 1 (zeige PON1 Proteine)/2/3 knockout or transgenic mice, as well as humans - healthy volunteers and atherosclerotic patients.

  7. The directed evolution and characterization of recombinant variants of serum paraoxonase PON3, is described.

Rabbit Paraoxonase 3 (PON3) Interaktionspartner

  1. The directed evolution and characterization of recombinant variants of serum paraoxonase PON3, is described.

Pig (Porcine) Paraoxonase 3 (PON3) Interaktionspartner

  1. Results show that PON3 mRNA and protein are ubiquitously expressed in pig tissues. Moreover, the relative abundance of PON3 mRNA, measured in perirenal and subcutaneous fat tissues, is higher in obese gilts compared with the leaner (zeige CACNA1A Proteine) gilts.

Paraoxonase 3 (PON3) Protein Überblick

Protein Überblick

This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described\; however, only one has been fully characterized.

Alternative names and synonyms associated with Paraoxonase 3 (PON3)

  • paraoxonase 3 (PON3)
  • paraoxonase 3 (Pon3)
  • 2810004E20 Protein
  • AI786302 Protein

Bezeichner auf Proteinebene für Paraoxonase 3 Proteine (PON3)

paraoxonase 3 , serum paraoxonase/lactonase 3-like , serum paraoxonase/lactonase 3 , paraoxanase-3

699236 Macaca mulatta
100337686 Ovis aries
100408549 Callithrix jacchus
100436262 Pongo abelii
100603110 Nomascus leucogenys
463548 Pan troglodytes
510953 Bos taurus
5446 Homo sapiens
269823 Mus musculus
312086 Rattus norvegicus
100008754 Oryctolagus cuniculus
475235 Canis lupus familiaris
733674 Sus scrofa
100721546 Cavia porcellus
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