TUBB2B Proteine (TUBB2B)

Bezeichnung:
Tubulin, beta 2B Proteine (TUBB2B)
Auf www.antikoerper-online.de finden Sie aktuell 6 Tubulin, beta 2B (TUBB2B) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TUBB2B Antikörper (61) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 71 TUBB2B Produkte verfügbar.
Synonyme:
2410129E14Rik, bA506K6.1, fb40f09, N-Tub, n-tubulin, NBT, NST, ntubulin, PMGYSA, RGD1309427, TUBB, Tubb2, TUBB2A, TUBB2B, tubb2c, wu:fb40f09, Xn-tubulin
alle Proteine anzeigen Gen GeneID UniProt
TUBB2B 347733 Q9BVA1
TUBB2B 73710 Q9CWF2
TUBB2B 291081 Q3KRE8

Weitere Synonyme anzeigen

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Weitere Proteine zu TUBB2B Interaktionspartnern

Human Tubulin, beta 2B (TUBB2B) Interaktionspartner

  1. The TUBB2B mutation described here represents an unusual recessive mode of inheritance for missense-mediated tubulinopathies and reinforces the sensitivity of the developing cerebellum to microtubule defects.

  2. At the cellular level, the p.Cys239Phe TUBB2B mutant leads to tubulin (zeige TUBB Proteine) heterodimerization impairment, decreased ability to incorporate into the cytoskeleton, microtubule dynamics alteration, with an accelerated rate of depolymerization

  3. off-target, non-immune mediated effects of the mTOR (zeige FRAP1 Proteine)-inhibitor everolimus on the podocyte cytoskeleton might involve regulation of microtubules, revealing a potential novel role of TUBB2B and DCDC2 (zeige DCDC2 Proteine) in glomerular podocyte development

  4. The association of polymicrogyria with thin or absent corpus callosum, dysmorphic basal ganglia, brainstem and vermis hypoplasia is highly likely to result from mutations in TUBB2B.

  5. The present study confirms that mutations in tubulin (zeige TUBB Proteine) genes are responsible for complex brain malformation.

  6. Congenital fibrosis of the extraocular muscles and intellectual disability segregate with a heterozygous mutation in TUBB2B.

  7. The TUBB2B and TUBA1 (zeige TUBA4A Proteine) coding regions have been sequenced in patients with cortical malformations associated with these genes.

  8. Three new TUBB2B mutations have been identified in three unrelated patients with a diffuse and rather symmetrical cortical abnormality.

  9. Brain malformations are associated with mutations in the beta-tubulin (zeige TUBB Proteine) gene TUBB2B, supporting its critical role in migration/organization and axon guidance processes.

  10. TUBB2B is required for neuronal migration two disease-associated mutations lead to impaired formation of tubulin (zeige TUBB Proteine) heterodimers.

Mouse (Murine) Tubulin, beta 2B (TUBB2B) Interaktionspartner

  1. The data presented here demonstrate that a heterozygous Tubb2b brdp/+ mutation in mice leads to significant spatial learning and memory reductions and conditioned contextual, but not cued, fear deficits.

  2. study shows TUBB2B significantly upregulated in melanoma multinucleated giant cells, which indicates that it may play an important role in melanoma metastasis.

  3. Study showed that Tubb2b is expressed in Sox2 (zeige SOX2 Proteine)- and Tbr2 (zeige EOMES Proteine)-positive neuronal progenitors and, at higher levels, in Dcx (zeige DCX Proteine)-positive postmitotic neurons in the developing mouse neocortex

  4. Results show that the missense mutation at a highly conserved residue (N247S) in Tubb2b gene represents the most severely affected mouse tubulin (zeige TUBB Proteine) phenotype involving neuronal proliferation and survival.

Cow (Bovine) Tubulin, beta 2B (TUBB2B) Interaktionspartner

  1. A combination of molecular dynamics simulations and computational docking is used to identify a single high-affinity binding site on five beta-tubulin (zeige TUBB Proteine) microtubule inhibitors adjacent to the exchangeable GTP (zeige AK3 Proteine) site on beta-tubulin (zeige TUBB Proteine).

  2. Results suggest that the axonemal motif sequences of betaI, betaIV and betaV tubulin (zeige TUBB Proteine) are essential for ciliary function.

  3. These data indicate that phosphorylation of tubulin (zeige TUBB Proteine) by Cdk1 (zeige CDK1 Proteine) could be involved in the regulation of microtubule dynamics during mitosis.

TUBB2B Protein Überblick

Protein Überblick

The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria.

Alternative names and synonyms associated with TUBB2B

  • tubulin, beta 2b (tubb2b)
  • tubulin, beta 2B class IIb (tubb2b)
  • tubulin, beta 2B class IIb (TUBB2B)
  • tubulin, beta 2B (TUBB2B)
  • hypothetical protein (MW1385)
  • tubulin, beta 2B class IIB (Tubb2b)
  • tubulin, beta 2B class IIb (Tubb2b)
  • 2410129E14Rik Protein
  • bA506K6.1 Protein
  • fb40f09 Protein
  • N-Tub Protein
  • n-tubulin Protein
  • NBT Protein
  • NST Protein
  • ntubulin Protein
  • PMGYSA Protein
  • RGD1309427 Protein
  • TUBB Protein
  • Tubb2 Protein
  • TUBB2A Protein
  • TUBB2B Protein
  • tubb2c Protein
  • wu:fb40f09 Protein
  • Xn-tubulin Protein

Bezeichner auf Proteinebene für Tubulin, beta 2B Proteine (TUBB2B)

tubulin, beta 2b , neural beta-tubulin , tubb-paralog , tubulin, beta 2 , beta-tubulin class-II , tubulin beta-2 chain , tubulin, beta 2B , hypothetical protein , class II beta-tubulin isotype , class IIb beta-tubulin , tubulin beta-2B chain , tubulin, beta polypeptide paralog , tubulin, beta 2A class IIa , tubulin, beta polypeptide , beta-tubulin T beta15 (aa 1-445) , t beta-15

GENE ID SPEZIES
322003 Danio rerio
394889 Xenopus (Silurana) tropicalis
420883 Gallus gallus
462400 Pan troglodytes
478702 Canis lupus familiaris
1003497 Staphylococcus aureus subsp. aureus MW2
100021036 Monodelphis domestica
347733 Homo sapiens
73710 Mus musculus
281555 Bos taurus
291081 Rattus norvegicus
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