Stathmin 1 Proteine (STMN1)

Auf www.antikoerper-online.de finden Sie aktuell 28 Stathmin 1 (STMN1) Proteine von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Stathmin 1 Antikörper (358) und Stathmin 1 Kits (42) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 447 Stathmin 1 Produkte verfügbar.
Synonyme:
19k, C1orf215, cb959, fj43c10, Lag, Lap18, LOC100217988, Op18, P18, P19, Pig, Pp17, Pp18, Pp19, Pr22, prosolin, Smn, stathmin, stmn1, stmn1a, wu:fb14e04, wu:fj38b07, wu:fj43c10, zgc:110159, zgc:136942
alle Proteine anzeigen Gen GeneID UniProt
STMN1 3925 P16949
STMN1 16765 P54227
STMN1 29332 P13668

Stathmin 1 Proteine (STMN1) nach Spezies

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Human Stathmin 1 (STMN1) Interaktionspartner

  1. Our finding demonstrates that RSK2 (zeige RPS6KA3 Proteine) directly phosphorylates stathmin and regulates microtubule polymerization to provide a pro-invasive and pro-metastatic advantage to cancer cells. Therefore, the RSK2 (zeige RPS6KA3 Proteine)-stathmin pathway represents a promising therapeutic target and a prognostic marker for metastatic human cancers.

  2. stathmin expression was significantly associated with shorter progression-free survival and overall survival for all analyzed cases of endometrial cancer; findings demonstrate that high stathmin expression is a poor prognostic marker in endometrial cancer

  3. Integrin beta1 appears to serve as a partner of Stathmin induction of ERK (zeige EPHB2 Proteine) and Akt (zeige AKT1 Proteine) signaling by inhibiting apoptosis in the cholangiocarcinoma cell.

  4. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in gastric cancer (GC) and could be a novel therapeutic target in metastatic GC.

  5. STMN1,COF1 (zeige CFL1 Proteine) and PAIRBP1 (zeige SERBP1 Proteine) thus represent proteins associated with proliferative and aggressive tumors of high grades, while TSP2 (zeige THBS2 Proteine) and POSTN (zeige POSTN Proteine) were connected to low grade tumors with better prognosis

  6. The phosphorylation-specific association of STMN1 with GRP78 (zeige HSPA5 Proteine) promotes breast cancer metastasis.

  7. hese results suggested that STMN1 plays an important role in proliferation and migration of hypopharyngeal squamous cell carcinoma and may be used as a potential prognostic biomarker or therapeutic target of hypopharyngeal squamous cell carcinoma (HSCC) .

  8. High STMN1 expression is associated with invasion in endometrial carcinoma.

  9. High expression of stathmin 1 predicts poor outcome in oral squamous cell carcinoma patients treated by docetaxel-containing regimens.

  10. The expressions of TYMS (zeige TYMS Proteine), TUBB3 (zeige TUBB3 Proteine) and STMN1 were significantly associated with the clinicopathological characteristics of age, gender and family history of gastric cancer, but not with differentiation, growth patterns, metastasis and TNM (zeige ODZ1 Proteine) staging in patients with gastric cancer.

Mouse (Murine) Stathmin 1 (STMN1) Interaktionspartner

  1. EGFR (zeige EGFR Proteine) suppression of mitotic regulators including Rcc2 (zeige RCC2 Proteine) and Stathmin 1 are a mechanism for catagen induction in mouse skin

  2. We identified stathmin as a key molecule aiding in septin (zeige SEPT6 Proteine)-independent cytokinesis, demonstrated that stathmin supplementation is sufficient to override cytokinesis failure in SEPT7 (zeige SEPT7 Proteine)-null fibroblasts

  3. Overexpressing stathmin reduces complement receptor 3 (zeige ITGAM Proteine)-mediated phagocytosis and cellular activation, implicating a pivotal inhibitory role for stathmin in classically activated macrophages.

  4. Stathmin cooperates with p27(kip1 (zeige CDKN1B Proteine)) to control the early phase of G1 to S phase transition and that this function may be of particular relevance in the context of tumor progression.

  5. The protein profiles during murine embryo implantation were clarified. Stathmin 1 might be a potential regulator of embryo implantation.

  6. Results show an important role for stathmin during adult neurogenesis in the subgranular zone of the mouse hippocampus; propose that stathmin controls the transition from neuronal precursors to early postmitotic neurons

  7. Stathmin mutations disrupt changes in microtubule stability, GluA2 (zeige GRIA2 Proteine) localization, synaptic plasticity and memory.

  8. Stmn deletion does not prolong the lifespan of spinal muscular atrophy-like mice, suggesting that stathmin dysregulation and microtubule disruption are not a cause but rather a consequence of SMA (zeige SMN1 Proteine) pathology.

  9. stathmin expression is dispensable for tumor onset, at least in mice, thus making stathmin a virtually exclusive marker of aggressive disease and a promising therapeutic target for advanced cancers.

  10. results demonstrate the mechanism of stathmin-dependent control of MT dynamics, Rho signaling, and permeability

Stathmin 1 (STMN1) Protein Überblick

Protein Überblick

This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Stathmin 1 (STMN1)

  • stathmin 1 (stmn1-a)
  • stathmin 1 (STMN1)
  • stathmin 1 (stmn1)
  • stathmin 1b (stmn1b)
  • stathmin 1a (stmn1a)
  • stathmin 1/oncoprotein 18 (LOC100217988)
  • stathmin 1/oncoprotein 18 (LOC100229194)
  • stathmin (stmn1)
  • stathmin 1 (Stmn1)
  • 19k Protein
  • C1orf215 Protein
  • cb959 Protein
  • fj43c10 Protein
  • Lag Protein
  • Lap18 Protein
  • LOC100217988 Protein
  • Op18 Protein
  • P18 Protein
  • P19 Protein
  • Pig Protein
  • Pp17 Protein
  • Pp18 Protein
  • Pp19 Protein
  • Pr22 Protein
  • prosolin Protein
  • Smn Protein
  • stathmin Protein
  • stmn1 Protein
  • stmn1a Protein
  • wu:fb14e04 Protein
  • wu:fj38b07 Protein
  • wu:fj43c10 Protein
  • zgc:110159 Protein
  • zgc:136942 Protein

Bezeichner auf Proteinebene für Stathmin 1 Proteine (STMN1)

oncoprotein 18 , stathmin 1 a , stathmin 1/oncoprotein 18 , fj38b07 , stathmin 1/oncoprotein 18b , stathmin 1 , stathmin , leukemia-associated phosphoprotein p18 , metablastin , phosphoprotein 19 , phosphoprotein p19 , prosolin , transmembrane protein C1orf215 , leukemia associated phosphoprotein p18 , leukemia-associated gene protein , leukemia-associated cytosolic phosphoprotein stathmin , stathmin-1

GENE ID SPEZIES
380364 Xenopus laevis
456650 Pan troglodytes
493340 Xenopus (Silurana) tropicalis
550548 Danio rerio
678630 Danio rerio
100217988 Taeniopygia guttata
100229194 Taeniopygia guttata
100528882 Ictalurus punctatus
3925 Homo sapiens
16765 Mus musculus
29332 Rattus norvegicus
100732759 Cavia porcellus
396057 Gallus gallus
494463 Sus scrofa
616317 Bos taurus
478175 Canis lupus familiaris
101113917 Ovis aries
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