anti-RPS6KA3 (RPS6KA3) Antikörper

anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 Antikörper (RPS6KA3)
Auf finden Sie aktuell 153 Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RPS6KA3 Proteine (14) und RPS6KA3 Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 179 RPS6KA3 Produkte verfügbar.
CLS, HU-3, ISPK-1, MAPKAPK1B, MPK-9, MRX19, p90-RSK2, pp90RSK2, RSK, RSK2, S6K-alpha3
Alle Antikörper anzeigen Gen GeneID UniProt
RPS6KA3 110651 P18654
RPS6KA3 6197 P51812

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Meistgesuchte Reaktivitäten zu anti-RPS6KA3 (RPS6KA3) Antikörper

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anti-Mouse (Murine) RPS6KA3 Antikörper:

anti-Human RPS6KA3 Antikörper:

anti-Rat (Rattus) RPS6KA3 Antikörper:

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Am meisten referenzierte anti-RPS6KA3 Antikörper

  1. Human Polyclonal RPS6KA3 Primary Antibody für EIA - ABIN358394 : Yang, Matsuda, Bialek, Jacquot, Masuoka, Schinke, Li, Brancorsini, Sassone-Corsi, Townes, Hanauer, Karsenty: ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. in Cell 2004 (PubMed)
    Zeige alle 5 Referenzen für 358394

  2. Human Monoclonal RPS6KA3 Primary Antibody für ICC, FACS - ABIN969386 : Dehan, Bassermann, Guardavaccaro, Vasiliver-Shamis, Cohen, Lowes, Dustin, Huang, Taunton, Pagano: betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis. in Molecular cell 2009 (PubMed)
    Zeige alle 2 Referenzen für 969386

  3. Human Monoclonal RPS6KA3 Primary Antibody für EIA, IF - ABIN1108903 : Koutsilieris, Mitsiades, Bogdanos, Dimopoulos, Karamanolakis, Milathianakis, Tsintavis: Combination of somatostatin analog, dexamethasone, and standard androgen ablation therapy in stage D3 prostate cancer patients with bone metastases. in Clinical cancer research : an official journal of the American Association for Cancer Research 2004 (PubMed)

Weitere Antikörper gegen RPS6KA3 Interaktionspartner

Mouse (Murine) Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) Interaktionspartner

  1. The purified protein can be fully activated in vitro by phosphorylation with protein kinases ERK2 (zeige MAPK1 Antikörper) and PDK1 (zeige PDPK1 Antikörper).

  2. Downregulation of Rps6ka3 is a promising strategy for the treatment of multiple sclerosis.

  3. Data show that the phosphoinositide-dependent kinase 1 (PDK1 (zeige PDPK1 Antikörper))-p90 (zeige GPAM Antikörper) kDa ribosomal S6 kinases (Rsks) Rsk1 (zeige RPS6KA1 Antikörper)/2 pathway is critical for establishment and maintenance of a normal Langerhans cells (LC) network.

  4. RSK2 regulates craniofacial development including tooth development and patterning via novel transcriptional targets

  5. The results of this study show that RSK2 loss-of-function is associated in the dentate gyrus with multi-level alterations that encompass modifications of glutamate (zeige GRIN1 Antikörper) receptor channel properties, synaptic transmission.

  6. We propose that loss of function mutations in RSK2 that lead to Coffin-Lowry syndrome are related to defects in neuronal growth due to impaired RSK2-dependent PLD1 activity resulting in a reduced vesicle fusion rate and membrane supply.

  7. RSK2 interacted and phosphorylated GSK-3beta (zeige GSK3b Antikörper) at Ser9. Notably, GSK-3beta (zeige GSK3b Antikörper) phosphorylation at Ser9 was suppressed in RSK2(-/-) mouse embryonic fibroblasts.

  8. Pin1 (zeige PIN1 Antikörper) plays a critical role in tumorigenesis plausibly via physical interaction with RSK2 and reciprocal phosphorylation

  9. This study showed that RSK2 signaling contributes to morphine analgesia in the tail withdrawal response.

  10. Results show increased protein levels of Rsk1 (zeige RPS6KA1 Antikörper) and Rsk2 in the striatum of Huntington disease (zeige HTT Antikörper) mice and and striatal cells transfected with full-length mutant Huntingtin (zeige HTT Antikörper).

Human Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3) Interaktionspartner

  1. we discuss the function of the RSK2 signaling axis by interactions with binding partners in cancer development--{REVIEW}

  2. Results showed that RSK2 gene was overexpressed in osteosarcoma patients cells and its knockdown increased cell apoptosis, enhanced cell chemosensitivity, inhibits proliferation and migration, and weakened tumor formation.

  3. Upregulated expression of RSK2 is associated with breast cancer.

  4. Data show that the 90 kDa ribosomal protein S6 (zeige RPS6 Antikörper) kinases RSK1 (zeige RPS6KA1 Antikörper) and RSK2 play a key role in the homing of ovarian cancer cells in metastatic sites by regulating cell adhesion and invasion.

  5. RSK1 (zeige RPS6KA1 Antikörper) and 3 but not RSK2 are down-regulated in breast tumour and are associated with disease progression. RSK (zeige RPS6KA1 Antikörper) may be a key component in the progression and metastasis of breast cancer.

  6. This case is one of the few examples where RPS6KA3 mutations are associated with a non-specific X-linked mental retardation.

  7. Results indicate that the phosphorylation of EphA2 (zeige EPHA2 Antikörper) at Ser (zeige SIGLEC1 Antikörper)-897 is controlled by RSK (zeige RPS6KA1 Antikörper) and the RSK (zeige RPS6KA1 Antikörper)-EphA2 (zeige EPHA2 Antikörper) axis might contribute to cell motility and promote tumour malignant progression.

  8. miR (zeige MLXIP Antikörper)-191 represses proliferation in primary human fibroblasts via targeting multiple proto-oncogenes, including CDK9 (zeige CDK9 Antikörper), NOTCH2 (zeige NOTCH2 Antikörper), and RPS6KA3.

  9. This is the first report of exon skipping from an exonic mutation of RPS6KA3, demonstrating that a missense mutation and concomitant disruption of normal splicing contribute to the manifestation of CLS (zeige CLS Antikörper)

  10. SL0101 and BI-D1870 induce distinct off-target effects in mTORC1-p70S6K (zeige RPS6KB1 Antikörper) signaling, and thus, the functions previously ascribed to RSK1 (zeige RPS6KA1 Antikörper)/2 based on these inhibitors should be reassessed.

RPS6KA3 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Alternative names and synonyms associated with RPS6KA3

  • ribosomal protein S6 kinase polypeptide 3 (Rps6ka3) Antikörper
  • ribosomal protein S6 kinase, 90kDa, polypeptide 3 (RPS6KA3) Antikörper
  • CLS Antikörper
  • HU-3 Antikörper
  • ISPK-1 Antikörper
  • MAPKAPK1B Antikörper
  • MPK-9 Antikörper
  • MRX19 Antikörper
  • p90-RSK2 Antikörper
  • pp90RSK2 Antikörper
  • RSK Antikörper
  • RSK2 Antikörper
  • S6K-alpha3 Antikörper

Bezeichner auf Proteinebene für RPS6KA3

90 kDa ribosomal protein S6 kinase 3 , MAP kinase-activated protein kinase 1b , MAPK-activated protein kinase 1b , MAPKAP kinase 1b , MAPKAPK-1b , RSK-2 , S6K-alpha-3 , p90-RSK 3 , p90RSK3 , ribosomal S6 kinase 2 , ribosomal protein S6 kinase 2 , ribosomal protein S6 kinase alpha-3 , insulin-stimulated protein kinase 1

110651 Mus musculus
6197 Homo sapiens
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