MAPK3 Proteine (MAPK3)

Mitogen-Activated Protein Kinase 3 Proteine (MAPK3)
Auf finden Sie aktuell 36 Mitogen-Activated Protein Kinase 3 (MAPK3) Proteine von 11 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAPK3 Antikörper (512) und MAPK3 Kits (42) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 621 MAPK3 Produkte verfügbar.
ATMAPK3, ATMPK3, Erk-1, Erk1, Ert2, Esrk1, fi06b09, HS44KDAP, HUMKER1A, MAPK1, mitogen-activated protein kinase 3, MNK1, Mtap2k, p44, p44-ERK1, p44-MAPK, p44erk1, p44mapk, Prkm3, T6D9.4, Tb08.10J17.940, wu:fi06b09, zERK1
alle Proteine anzeigen Gen GeneID UniProt
MAPK3 5595 P27361
MAPK3 26417 Q63844
MAPK3 50689 P21708

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Am meisten referenzierte MAPK3 Proteine

  1. Human MAPK3 Protein expressed in Escherichia coli (E. coli) - ABIN667192 : Kim, Cochran: Extracellular signal-regulated kinase binds to TFII-I and regulates its activation of the c-fos promoter. in Molecular and cellular biology 2000 (PubMed)

Weitere Proteine zu MAPK3 Interaktionspartnern

Arabidopsis thaliana Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

  1. MKK4 (zeige MAP2K4 Proteine), MKK5 (zeige MAP2K5 Proteine), MKK7 (zeige MAP2K7 Proteine), and MKK9, are responsible for the activation of MPK3 and MPK6 (zeige MAPK6 Proteine) by melatonin, indicating that melatonin-mediated innate immunity is triggered by MAPK (zeige MAPK1 Proteine) signaling through MKK4 (zeige MAP2K4 Proteine)/5/7/9-MPK3/6 cascades.

  2. Phosphatase AP2C1, as well as AP2C1-targeted MPK3 and MPK6 (zeige MAPK6 Proteine), are important regulators of plant-nematode interaction, where the co-ordinated action of these signalling components ensures the timely activation of plant defence.

  3. Results demonstrated the contribution of MPK3 and MPK6 (zeige MAPK6 Proteine) to riboflavin-induced resistance.

  4. These results indicate that the MVB pathway is positively regulated by pathogen-responsive MPK3/6 through LIP5 phosphorylation and plays a critical role in plant immune system

  5. MKK3-MPK6 is activated by blue light in a MYC2-dependent manner.

  6. MPK3 and MPK6 (zeige MAPK6 Proteine) target a subclass of 'VQ-motif'-containing proteins to regulate immune responses.

  7. MicroRNA biogenesis factor DRB1 (zeige EPHX1 Proteine) is a phosphorylation target of mitogen activated protein kinase (zeige MAPK1 Proteine) MPK3 in both rice and Arabidopsis

  8. MPK3 represses the constitutive and flg22-induced expression of defence genes in Arabidopsis thaliana.

  9. These results suggest that the MKK9-MPK3/MPK6 (zeige MAPK6 Proteine) cascade is part of the phosphate signaling pathway in plants.

  10. AZI1 overexpression in the mpk3 genetic background partially alleviates the salt-hypersensitive phenotype of this mutant, but functional MPK3 appears to be required for the full extent of AZI1-conferred robustness.

Cow (Bovine) Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

  1. MAPK3/1 is involved in luteinizing hormone-mediated decrease of C-type natriuretic peptide (zeige NPPC Proteine) and this process is related to the EGFR (zeige EGFR Proteine) and MAPK3/1 signal pathways

  2. Chronic hypoxia induces Egr-1 via activation of ERK1/2 and contributes to pulmonary vascular remodeling.

  3. ER Ca(2+) release enhances eNOS Ser-635 phosphorylation and function via ERK1/2 activation.

  4. Thrombospondin 1 (zeige THBS1 Proteine), fibronectin (zeige FN1 Proteine), and vitronectin (zeige VTN Proteine) are differentially dependent upon RAS, ERK1/2, and p38 (zeige MAPK14 Proteine) for induction of vascular smooth muscle cell chemotaxis.

  5. results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation

  6. These data suggest that Gab1-ERK1/2 binding and their nuclear translocation play a crucial role in Egr-1 (zeige EGR1 Proteine) nuclear accumulation.

  7. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt, mTOR, p70S6K, and ERK1/2.

  8. This study demonstrates for the first time that cyclic mechanical stretch induces the proliferation of bovine satellite cells and suppresses their myogenic differentiation through the activation of ERK (zeige MAPK1 Proteine).

  9. findings indicate that exposure to DHEA, at concentrations found in human blood, causes vascular endothelial proliferation by a plasma membrane-initiated activity that is Gi/o and ERK1/2 dependent.

  10. Results suggest that estrogen receptors and the ERK1/2 signaling pathway are involved in the anti-apoptotic action of LY117018 in vascular endothelial cells.

Candida albicans Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

  1. Cek2 (zeige FGFR3 Proteine) has a cryptic role in cell-wall biogenesis and its role is not entirely redundant to Cek1.

  2. knockdown of SUV420H1 (zeige SUV420H1 Proteine) reduced phosphorylated ERK1 and total ERK1 proteins, and interestingly suppressed ERK1 at the transcriptional level

  3. Secreted aspartic protease-mediated proteolytic cleavage of Msb2 is required for activation of the Cek1 mitogen activated protein kinase (zeige MAPK1 Proteine) pathway in response to environmental cues.

  4. The authors propose that a Msb2, Cek1 and Ace2 signalling pathway addresses PMT genes as downstream targets and that different modes of regulation have evolved for PMT1 and PMT2/PMT4 genes.

  5. Msb2 is involved in the transmission of the signal toward Cek1 mediated by the Cdc42 (zeige CDC42 Proteine) GTPase (zeige RACGAP1 Proteine).

Zebrafish Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

  1. ERK1/2-Akt1 (zeige AKT1 Proteine) crosstalk regulates arteriogenesis in mice and zebrafish.

  2. eena (zeige SH3GL1 Proteine) plays an important role in the development of the myeloid cell through activation of the ERK1/ERK2 (zeige MAPK1 Proteine) pathway

  3. ERK1 and ERK2 (zeige MAPK1 Proteine) target common and distinct gene sets, confirming diverse roles for these kinases during embryogenesis; for ERK1 different specific genes involved in dorsal-ventral patterning and subsequent embryonic cell migration were identified.

  4. These results demonstrate that induction of Hsp70 (zeige HSPA1A Proteine) in response to heat stress is dependent on ERK (zeige MAPK1 Proteine) activation in Pac2 (zeige PSMG2 Proteine) cells.

  5. Data define distinct roles for ERK1 and ERK2 (zeige MAPK1 Proteine) in developmental cell migration processes during zebrafish embryogenesis.

Human Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

  1. findings uncover a role of ERK1 in the regulation of furin (zeige FURIN Proteine) activity by supporting a self-sustaining loop for high TGF-beta (zeige TGFB1 Proteine) activity in glioma-initiating cells.

  2. Bile duct adenocarcinoma cells overexpress claudin-18 (zeige CLDN18 Proteine) via the EGFR (zeige EGFR Proteine)/RAS/ERK (zeige EPHB2 Proteine) pathway, contributing to cell proliferation and invasion.

  3. Genome-wide gene expression profiling identified a network of VEGF (zeige VEGFA Proteine)-responsive and ERG (zeige ERG Proteine)-dependent genes.

  4. Finally, the authors show that EGFR (zeige EGFR Proteine)-ERK1/2 and beta1-integrin signaling are the main pathways used for bacteria-mediated EGR1 (zeige EGR1 Proteine) upregulation.

  5. ERK1 phosphorylation is mediated by Src (zeige SRC Proteine) and Csk (zeige CSK Proteine).

  6. Integrin beta1 appears to serve as a partner of Stathmin (zeige STMN1 Proteine) induction of ERK (zeige EPHB2 Proteine) and Akt (zeige AKT1 Proteine) signaling by inhibiting apoptosis in the cholangiocarcinoma cell.

  7. Aberrant expression of sema3c is correlated with poor prognosis of pancreatic ductal adenocarcinoma patients and promotes tumor growth and metastasis by activating ERK1/2 signaling pathway.

  8. Increased staining for phosphorylated ERK1/2 does not correlate to BRAF or KRAS mutations in colorectal neoplasms.

  9. Mutations of MAP2K1 (zeige MAP2K1 Proteine) are frequent in pediatric-type follicular lymphoma and result in ERK1/ERK2 (zeige MAPK1 Proteine) pathway activation.

  10. Data show that succinate upregulates vascular endothelial growth factor (VEGF) expression by activation of signal transducer and activator of transcription 3 (STAT3 (zeige STAT3 Proteine)) and extracellular regulated kinase (ERK)1/2 via its receptor G-protein coupled receptor 91 (GPR91 (zeige SUCNR1 Proteine)).

Mouse (Murine) Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

  1. Studies indicate that progesterone receptor transgenic (Pgrcre/+) mitogen inducible gene 6 (Mig-6over) phosphatase and tensin homolog protein (Ptenf/f) knockout mice exhibited an increase of phospho-ERK1/2 and its target genes.

  2. Gpr182 reduction led to increased activation of ERK1/2 in basal and challenge models, demonstrating a potential role for this orphan GPCR in regulating the proliferative capacity of the intestine.

  3. ERK1 underexpression is associated with obesity.

  4. retinoschisin (zeige RS1 Proteine) is a novel regulator of MAP kinase (zeige MAPK1 Proteine) signalling and exerts an anti-apoptotic effect on retinal cells.

  5. Postnatal chondrocyte-specific deletion of Hdac3 (zeige HDAC3 Proteine) with an inducible Col2a1 (zeige COL2A1 Proteine)-Cre caused premature production of pErk1/2 and Mmp13 (zeige MMP13 Proteine) in the growth plate.

  6. The progress of neurogenesis depended on sustained ERK phosphorylation and resulted in ERK1/2 translocation to the nucleus.

  7. Mirtazapine suppressed 5-HT-mediated TGF-beta1/Smad3 and ERK1/2 signaling pathways as well as oxidative stress that contribute to the progression of liver fibrosis.

  8. The kinase TPL2 (zeige MAP3K8 Proteine) activates ERK (zeige EPHB2 Proteine) and p38 (zeige CRK Proteine) signaling to promote neutrophilic inflammation

  9. HAS2 (zeige HAS2 Proteine)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1/EGR1 (zeige EGR1 Proteine) signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (zeige TGFB1 Proteine)-stimulated CD44V6/ERK (zeige EPHB2 Proteine)/EGR1 (zeige EGR1 Proteine) signaling.

  10. We also demonstrated that ERK1 deletion potentiates DC vaccination and provides a survival advantage in high-grade gliomas.

Pig (Porcine) Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

  1. Pseudorabies virus glycoprotein gE-mediated ERK 1/2 phosphorylation also occurs in epithelial cells and in these cells, gE-mediated ERK 1/2 signaling is associated with degradation of the pro-apoptotic protein Bim (zeige BCL2L11 Proteine).

  2. Treatment with ERK inhibitors or ERK1/2 knockdown significantly suppressed porcine epidemic diarrhea virus progeny production.

  3. This study reveals a new function of the gE glycoprotein of pseudorabies virus and suggests that pseudorabies virus, through activation of ERK1/2 signaling, has a substantial impact on T cell behavior.

  4. CSF2 (zeige CSF2 Proteine) stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 MAPK (zeige MAPK1 Proteine)-dependent MTOR (zeige FRAP1 Proteine) signal transduction cascades.

  5. PGRN (zeige GRN Proteine) inhibits adipogenesis in porcine preadipocytes partially through ERK (zeige MAPK1 Proteine) activation mediated PPARgamma (zeige PPARG Proteine) phosphorylation.

  6. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK (zeige PRKAA1 Proteine)/ERK (zeige MAPK1 Proteine)/TSC2/mTOR (zeige FRAP1 Proteine) signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

  7. Data show that proinflammatory cytokines induction was ERK1/2 and JNK1 (zeige MAPK8 Proteine)/2 dependent.

  8. Saccharomyces cerevisiae inhibits the Enterotoxigenic Escherichia coli-induced expression of pro-inflammatory transcripts and this inhibition was associated to a decrease of ERK1/2 and p38 MAPK (zeige MAPK14 Proteine) phosphorylation

  9. ERK1 phosphorylation in response to Insulin-like Growth Factor-1 (zeige IGF1 Proteine) does not require activation of the Insulin-like Growth Factor-1 receptor tyrosine kinase (zeige IGF1R Proteine)

  10. Retinal ischemia-reperfusion alters expression of mitogen-activated protein kinases, particularly ERK1/2, in the neuroretina and retinal arteries.

MAPK3 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Alternative names and synonyms associated with MAPK3

  • mitogen-activated protein kinase 3 (MPK3)
  • mitogen-activated protein kinase 3 (MAPK3)
  • MAP kinase-like orf; aka CEK1; one of two protein kinase genes similar to S. cerevisiae MAP kinases FUS3 (YBL016W) and KSS1 (YGR040W) involved in pheromone signal transduction (ERK1)
  • mitogen-activated protein kinase 3 (Mapk3)
  • mitogen-activated protein kinase 3 (mapk3)
  • mitogen activated protein kinase 3 (Mapk3)
  • mitogen-activated protein kinase 3 (Tb927.8.3550)
  • mitogen-activated protein kinase 3 (Tc00.1047053509475.10)
  • ATMAPK3 Protein
  • ATMPK3 Protein
  • Erk-1 Protein
  • Erk1 Protein
  • Ert2 Protein
  • Esrk1 Protein
  • fi06b09 Protein
  • HS44KDAP Protein
  • HUMKER1A Protein
  • MAPK1 Protein
  • mitogen-activated protein kinase 3 Protein
  • MNK1 Protein
  • Mtap2k Protein
  • p44 Protein
  • p44-ERK1 Protein
  • p44-MAPK Protein
  • p44erk1 Protein
  • p44mapk Protein
  • Prkm3 Protein
  • T6D9.4 Protein
  • Tb08.10J17.940 Protein
  • wu:fi06b09 Protein
  • zERK1 Protein

Bezeichner auf Proteinebene für MAPK3

extracellular signal-regulated kinase 1 , likely protein kinase , MAP kinase isoform p44 , MAPK 1 , extracellular signal-related kinase 1 , insulin-stimulated MAP2 kinase , microtubule-associated protein 2 kinase , MAP kinase 3 , p44 MAP kinase , pp42/MAP kinase , MAP kinase 1 , MAPK 3 , mitogen-activated 3 , mitogen-activated protein kinase 1 , mitogen-activated protein kinase 3 , extracellular signal-regulated kinase-1

823706 Arabidopsis thaliana
531391 Bos taurus
3642789 Candida albicans SC5314
479790 Canis lupus familiaris
100725692 Cavia porcellus
399480 Danio rerio
100066173 Equus caballus
5595 Homo sapiens
26417 Mus musculus
50689 Rattus norvegicus
445013 Sus scrofa
3659358 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3531528 Trypanosoma cruzi strain CL Brener
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