anti-MAPK14 (MAPK14) Antikörper

Auf www.antikoerper-online.de finden Sie aktuell 196 Mitogen-Activated Protein Kinase 14 (MAPK14) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAPK14 Kits (48) und MAPK14 Proteine (38) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 313 MAPK14 Produkte verfügbar.
Synonyme:
186F5S, anon-sts23, AP22.98, AP22_98, ATMPK14, BG:DS00797.3, CG7393, CRK1, csbp, Csbp1, Csbp2, CSPB1, D-p38, D-p38 MAPK, D-p38b, Dmel\\CG7393, Dmp38b, Dm p38b, Dp38, dp38b, ESTS:186F5S, Exip, Hog, mapk14a, mitogen-activated protein kinase 14, Mpk34C, mxi2, p38, p38 beta, p38 MAPK, p38-alpha, p38a, p38alpha, p38B, p38beta, p38Hog, p38Kb, p38MAPK, Prkm14, Prkm15, RK, sapk2, sapk2a
Alle Antikörper anzeigen Gen GeneID UniProt
MAPK14 1432 Q16539
MAPK14 26416 P47811
MAPK14 81649  

Meistgesuchte Reaktivitäten zu anti-MAPK14 (MAPK14) Antikörper

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Weitere Antikörper gegen MAPK14 Interaktionspartner

Cow (Bovine) Mitogen-Activated Protein Kinase 14 (MAPK14) Interaktionspartner

  1. results suggest that ET-1 (zeige EDN1 Antikörper)-induced activation of proMMP-2 is mediated via cross-talk between NADPH oxidase (zeige NOX1 Antikörper)-PKCalpha (zeige PKCa Antikörper)-p(38)MAPK (zeige MAPK1 Antikörper) and NFkappaB-MT1MMP (zeige MMP14 Antikörper) signaling pathways along with a marked decrease in TIMP-2 (zeige TIMP2 Antikörper) expression in the cells

  2. cross-talk between p(38)MAPK (zeige MAPK1 Antikörper) and Gialpha play a pivotal role for full activation of cPLA2 (zeige PLA2G4A Antikörper) during ET-1 (zeige EDN1 Antikörper) stimulation of pulmonary artery smooth muscle cells.

  3. MAPK14 signalling pathway is largely involved in heat-induced sperm damage.

  4. p38 MAPK is an early redox sensor in the laminar shear stress with hydrogen peroxide being a signaling mediator.

  5. Blockade of p38 enhances chondrocyte phenotype in monolayer culture and may promote more efficient cartilage tissue regeneration for cell-based therapies.

  6. p38 phosphorylation and MMP13 (zeige MMP13 Antikörper) expression are regulated by Rho/ROCK activation, and support the potential novel pathway that Rho/ROCK is in the upper part of the mechanical stress-induced matrix degeneration cascade in cartilage.

  7. These data suggest that the p38 and JNK (zeige MAPK8 Antikörper) signaling pathways play pivotal roles in PRRSV replication and may regulate immune responses during virus infection.

  8. findings support the hypothesis that ischemic factor stimulation of the blood-brain barrier Na-K-Cl cotransporter (zeige SLC12A1 Antikörper) involves activation of p38 and JNK (zeige MAPK8 Antikörper) MAPKs

  9. These data suggest a differential requirement of JNK1 (zeige MAPK8 Antikörper) and p38 MAPK in TNF (zeige TNF Antikörper) regulation of E2F1 (zeige E2F1 Antikörper). Targeted inactivation of JNK1 (zeige MAPK8 Antikörper) at arterial injury sites may represent a potential therapeutic intervention for ameliorating TNF (zeige TNF Antikörper)-mediated EC dysfunction.

  10. p38 MAPK (MAPK14) is redox-regulated in reactive oxygen species-dependent endothelial barrier dysfunction.

Fruit Fly (Drosophila melanogaster) Mitogen-Activated Protein Kinase 14 (MAPK14) Interaktionspartner

  1. ROS (zeige ROS1 Antikörper)/JNK (zeige MAPK8 Antikörper)/p38/Upd (zeige UROD Antikörper) stress responsive module restores tissue homeostasis. This module is not only activated after cell death induction but also after physical damage and reveals one of the earliest responses for imaginal disc regeneration.

  2. Taken together, our findings indicate that the p38 MAP Kinase is an integral component of the core circadian clock of Drosophila in addition to playing a role in stress-input pathways.

  3. Data show that the genetic interaction between p38b MAPK (zeige MAPK1 Antikörper) and Rack1 (zeige GNB2L1 Antikörper) controls muscle aggregate formation, locomotor function, and longevity.

  4. The interaction of any of several Drosophila Delta class glutathione transferases and p38b mitogen-activated protein kinase (zeige MAPK1 Antikörper) can affect the substrate specificity of either enzyme, which suggests induced conformational changes affecting catalysis.

  5. found a correlation between the depth of integration of individual p38 kinases into the protein interaction network and their functional significance; propose a central role of p38b in the p38 signaling module with p38a and p38c playing more peripheral auxiliary roles

  6. Loss of p38 MAPK causes early lethality and precipitates age-related motor dysfunction and stress sensitivity.

  7. The p38 pathway-mediated stress response contribute to Drosophila host defense against microbial infection.

  8. p38b MAPK (zeige MAPK1 Antikörper) plays a crucial role in the balance between intestinal stem cell proliferation and proper differentiation in the adult Drosophila midgut.

  9. the D-p38b gene is regulated by the DREF (zeige ZBED1 Antikörper) pathway and DREF (zeige ZBED1 Antikörper) is involved in the regulation of proliferation and differentiation of Drosophila ISCs (zeige NFS1 Antikörper) and progenitors

Horse (Equine) Mitogen-Activated Protein Kinase 14 (MAPK14) Interaktionspartner

  1. p38 mitogen-activated protein kinase is crucial for bovine papillomavirus type-1 transformation of equine fibroblasts.

  2. p38 Mitogen-activated protein kinase (MAPK (zeige MAPK1 Antikörper)) is essential for drug-induced COX-2 (zeige PTGS2 Antikörper) expression in leukocytes, suggesting that p38 MAPK is a potential target for anti-inflammatory therapy.

  3. These findings support a function for p38 MAPK in equine neutrophil migration and suggest the potential for the ability of p38 MAPK inhibition to limit neutrophilic inflammation in the laminae during acute laminitis.

  4. Cultured equine digital vein endothelial cells were exposed to lipopolysaccharide and phosphorylation of p38 MAPK was assessed by Western blotting using phospho-specific antibodies.

Human Mitogen-Activated Protein Kinase 14 (MAPK14) Interaktionspartner

  1. findings show that endothelial MAPKs ERK (zeige EPHB2 Antikörper), p38 (zeige CRK Antikörper), and JNK (zeige MAPK8 Antikörper) mediate diapedesis-related and diapedesis-unrelated functions of ICAM-1 (zeige ICAM1 Antikörper) in cerebral and dermal microvascular endothelial cells

  2. Tetraarsenic hexoxide (As4O6) induced G2/M arrest, apoptosis and autophagic cell death through PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) and p38 MAPK pathways alteration in SW620 colon cancer cells.

  3. The N-Terminal phosphorylation of RB by p38 (zeige CRK Antikörper) bypasses its inactivation by cyclin (zeige PCNA Antikörper)-dependent kinases and prevents proliferation in cancer cells.

  4. Inhibition of MAPK14 conclusively facilitates elucidation of the impact of the complex network of p38 MAPK signaling on atherogenesis.

  5. Collectively, this study provides more insights into RELT (zeige RELT Antikörper) expression, RELT (zeige RELT Antikörper) family member function, and the mechanism of RELT (zeige RELT Antikörper)-induced death.

  6. Data, including data from studies conducted in cells from transgenic/knockout mice, suggest that p38alpha MAPK (zeige MAPK1 Antikörper) (MAPK14) activity is required for hypoxia-induced pro-angiogenic activity involving cardiomyocytes and vascular endothelial cells; p38 MAPK activation in cardiomyocyte is sufficient to promote paracrine signaling-mediated, pro-angiogenic activity/myocardial revascularization.

  7. The findings indicate that p38alpha and GADD45alpha (zeige GADD45A Antikörper) are involved in an enhanced vitamin D signaling on TRPV6 (zeige TRPV6 Antikörper) expression.

  8. These results suggest that the p38 (zeige CRK Antikörper)/NPM (zeige NPM1 Antikörper)/PP2A (zeige PPP2R4 Antikörper) complex acts as a dynamic sensor, allowing endothelial cells to react rapidly to acute oxidative stress.

  9. Inhibition of the inflammatory signaling intermediate p38 MAPK reduced tissue factor (zeige F3 Antikörper) (TF) mRNA by one third but increased tumor necrosis factor (TNF (zeige TNF Antikörper)) and interleukin-1 beta (IL-1beta (zeige IL1B Antikörper)) mRNA.

  10. These results suggest that the activation of endogenous levels of SFK renders the endothelial barrier more susceptible to low, physiologic doses of TNF-alpha (zeige TNF Antikörper) through activation of p38 (zeige CRK Antikörper) which leads to a loss of endothelial tight junctions.

Mouse (Murine) Mitogen-Activated Protein Kinase 14 (MAPK14) Interaktionspartner

  1. Soluble epoxide hydrolase (zeige EPHX2 Antikörper) inhibitor AUDA decreases bleomycin-induced pulmonary toxicity in mice by inhibiting the p38 (zeige CRK Antikörper)/Smad3 (zeige SMAD3 Antikörper) signaling pathway.

  2. These results provide evidence supporting a key role for the p38 MAPK signaling pathway which is involved in the regulation of Abeta1-42 internalization in the parietal cortex and hippocampus of mouse through LRP1 (zeige LRP1 Antikörper) in vivo.

  3. The N-Terminal phosphorylation of RB by p38 (zeige CRK Antikörper) bypasses its inactivation by cyclin (zeige PCNA Antikörper)-dependent kinases and prevents proliferation in cancer cells.

  4. Quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting were used to detect the mRNA and protein expressions of p-p38MAPK, AAT (zeige SERPINA1A Antikörper), signal transducer and activator of transcription 1 (STAT1 (zeige STAT1 Antikörper)) and activating transcription factor2 (ATF2 (zeige ATF2 Antikörper))

  5. p38alpha is essential to maintain in actin dynamics with age in hepatocytes.

  6. Data, including data from studies conducted in cells from transgenic/knockout mice, suggest that p38alpha MAPK (zeige MAPK1 Antikörper) (Mapk14) activity is required for hypoxia-induced pro-angiogenic activity involving cardiomyocytes and vascular endothelial cells; p38 MAPK activation in cardiomyocyte is sufficient to promote paracrine signaling-mediated, pro-angiogenic activity/myocardial revascularization.

  7. blockage of NF-kappaB (zeige NFKB1 Antikörper) p65 (zeige NFkBP65 Antikörper) and/or MAPK p38 (zeige MAPK1 Antikörper) with their specific inhibitors strongly attenuated B7-H3 (zeige CD276 Antikörper)-amplified inflammatory response with significantly reduced proinflammatory cytokine and chemokine (zeige CCL1 Antikörper) production, and markedly ameliorated B7-H3 (zeige CD276 Antikörper)-exacerbated disruption of blood-brain barrier and severity of disease status in S. pneumoniae-infected mice.

  8. Data suggest that single muscle immobilization induces a shift of myosin heavy chain (MHC) isoforms composition toward a faster contractile phenotype and decreases the polymorphic profile of single fibres, and that activation of p38 and JNK could be a potential mechanism involved in these contractile phenotype modifications during muscle immobilization.

  9. The kinase TPL2 (zeige MAP3K8 Antikörper) activates ERK (zeige EPHB2 Antikörper) and p38 (zeige CRK Antikörper) signaling to promote neutrophilic inflammation

  10. studies have therefore uncovered a p38alpha-mediated pathway that alters Hematopoietic Stem/Progenitor Cell metabolism to respond to stress and promote recovery.

Rabbit Mitogen-Activated Protein Kinase 14 (MAPK14) Interaktionspartner

  1. These findings suggest that the TQ-induced production of ROS (zeige ROS1 Antikörper) causes dedifferentiation through the ERK (zeige MAPK1 Antikörper) pathway and inflammation through the PI3K and p38 pathways in rabbit articular chondrocytes.

  2. These results suggest that p38 MAPK signal transduction pathway is critical to NO-induced chondrocyte apoptosis, and p38 plays a role by way of stimulating NF-kappaB (zeige NFKB1 Antikörper), p53 (zeige TP53 Antikörper) and caspase-3 (zeige CASP3 Antikörper) activation.

Pig (Porcine) Mitogen-Activated Protein Kinase 14 (MAPK14) Interaktionspartner

  1. Porcine reproductive and respiratory syndrome virus strain CH-1a could significantly up-regulate IL-10 (zeige IL10 Antikörper) production through p38 MAPK activation.

  2. JNK (zeige MAPK8 Antikörper) plays an active role in fragmentation of pig oocytes and p38 MAPK is not involved in this process.[p38MAPK]

  3. Retinal ischemia-reperfusion alters expression of mitogen-activated protein kinases, particularly ERK1/2 (zeige MAPK1/3 Antikörper), in the neuroretina and retinal arteries.

Xenopus laevis Mitogen-Activated Protein Kinase 14 (MAPK14) Interaktionspartner

  1. cytochrome c (zeige CYCS Antikörper) microinjection induces p38 phosphorylation through caspase-3 (zeige CASP3 Antikörper) activation, and caspase (zeige CASP3 Antikörper) inhibition reduces p38 activation induced by osmostress, indicating that a positive feedback loop is engaged by hyperosmotic shock

MAPK14 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Alternative names and synonyms associated with MAPK14

  • mitogen-activated protein kinase 14 (MPK14) Antikörper
  • mitogen-activated protein kinase 14 (MAPK14) Antikörper
  • mitogen-activated protein kinase 14 (Mapk14) Antikörper
  • CG7393 gene product from transcript CG7393-RA (p38b) Antikörper
  • mitogen activated protein kinase 14 (Mapk14) Antikörper
  • mitogen-activated protein kinase 14 (mapk14) Antikörper
  • 186F5S Antikörper
  • anon-sts23 Antikörper
  • AP22.98 Antikörper
  • AP22_98 Antikörper
  • ATMPK14 Antikörper
  • BG:DS00797.3 Antikörper
  • CG7393 Antikörper
  • CRK1 Antikörper
  • csbp Antikörper
  • Csbp1 Antikörper
  • Csbp2 Antikörper
  • CSPB1 Antikörper
  • D-p38 Antikörper
  • D-p38 MAPK Antikörper
  • D-p38b Antikörper
  • Dmel\\CG7393 Antikörper
  • Dmp38b Antikörper
  • Dm p38b Antikörper
  • Dp38 Antikörper
  • dp38b Antikörper
  • ESTS:186F5S Antikörper
  • Exip Antikörper
  • Hog Antikörper
  • mapk14a Antikörper
  • mitogen-activated protein kinase 14 Antikörper
  • Mpk34C Antikörper
  • mxi2 Antikörper
  • p38 Antikörper
  • p38 beta Antikörper
  • p38 MAPK Antikörper
  • p38-alpha Antikörper
  • p38a Antikörper
  • p38alpha Antikörper
  • p38B Antikörper
  • p38beta Antikörper
  • p38Hog Antikörper
  • p38Kb Antikörper
  • p38MAPK Antikörper
  • Prkm14 Antikörper
  • Prkm15 Antikörper
  • RK Antikörper
  • sapk2 Antikörper
  • sapk2a Antikörper

Bezeichner auf Proteinebene für MAPK14

MAP kinase 14 , MAP kinase p38 alpha , MAPK 14 , mitogen-activated protein kinase p38 alpha , p38 mitogen activated protein kinase , CG7393-PA , p38 mitogen-activated protein kinase , p38b-PA , stress-activated p38b MAP kinase , p38 mitogen-activated kinase , cytokine suppressive anti-inflammatory drug binding protein 1 , mitogen activated protein kinase 14 , p38 MAP kinase alpha , p38 MAPK , p38 alpha , tRNA synthetase cofactor p38 , CSAIDS-binding protein 1 , mitogen-activated protein kinase 14A , stress-activated protein kinase 2a , Csaids binding protein , MAP kinase 2 , MAP kinase Mxi2 , MAX-interacting protein 2 , cytokine suppressive anti-inflammatory drug binding protein , cytokine-supressive anti-inflammatory drug binding protein , mitogen-activated protein kinase 14 , p38 MAP kinase , p38alpha Exip , reactive kinase , stress-activated protein kinase 2A , MAPK p38 , MPK2 , Mitogen-activated protein kinase 2 , mitogen-activated Mitogen-activated protein kinase 2

GENE ID SPEZIES
829797 Arabidopsis thaliana
534492 Bos taurus
403856 Canis lupus familiaris
100723285 Cavia porcellus
34780 Drosophila melanogaster
100063532 Equus caballus
421183 Gallus gallus
1432 Homo sapiens
26416 Mus musculus
100341695 Oryctolagus cuniculus
450161 Pan troglodytes
81649 Rattus norvegicus
100156630 Sus scrofa
379992 Xenopus laevis
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