MAP2K5 Proteine (MAP2K5)

Mitogen-Activated Protein Kinase Kinase 5 Proteine (MAP2K5)
Auf finden Sie aktuell 8 Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP2K5 Antikörper (179) und MAP2K5 Kits (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 205 MAP2K5 Produkte verfügbar.
AI324775, AI428457, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5, ATMAP2K_ALPHA, ATMEK5, ATMKK5, fb73f02, HsT17454, MAP2K_A, MAP kinase kinase 5, Mapkk5, MEK5, Prkmk5, wu:fb73f02, zgc:172137
alle Proteine anzeigen Gen GeneID UniProt
Ratte MAP2K5 MAP2K5 29568 Q62862
MAP2K5 5607 Q13163
MAP2K5 23938 Q9WVS7

Weitere Synonyme anzeigen

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Am meisten referenzierte MAP2K5 Proteine

  1. Human MAP2K5 Protein expressed in Wheat germ - ABIN1310183 : García-Hoz, Sánchez-Fernández, Díaz-Meco, Moscat, Mayor, Ribas: G alpha(q) acts as an adaptor protein in protein kinase C zeta (PKCzeta)-mediated ERK5 activation by G protein-coupled receptors (GPCR). in The Journal of biological chemistry 2010 (PubMed)
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Weitere Proteine zu MAP2K5 Interaktionspartnern

Human Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) Interaktionspartner

  1. Insights into a molecular mechanism by which MEK5 transcriptionally upregulated by Stat3 (zeige STAT3 Proteine) augments breast cancer cell EMT (zeige ITK Proteine), which subsequently enhances cancer cell invasion and metastasis. This finding may suggest that Stat3 (zeige STAT3 Proteine) and MEK5/Erk5 (zeige MAPK7 Proteine) pathways could be an effective therapeutic target for inhibition of breast cancer invasion and metastasis.

  2. Our findings confirm an association between the BTBD9, MEIS1, and MAP2K5/SKOR1 SNPs and periodic limb movements of sleep in an elderly cohort.

  3. Specifically, CKS1B (zeige CKS1B Proteine) and MAP2K5 significantly inhibited hepatitis C viral RNA replication. PACSIN1 (zeige PACSIN1 Proteine), by contrast, inhibited hepatitis C virus infection by decreasing the level of viral protein p7.

  4. High MEK5 expression is associated with colorectal cancer.

  5. SEC16B, MC4R, MAP2K5 and KCTD15 (rs17782313, rs543874, rs2241423 and rs11084753) polymorphisms are associated with the risk for children obesity in China.

  6. Periodic leg movements during sleep are associated with polymorphisms in BTBD9 (zeige BTBD9 Proteine), TOX3 (zeige TOX3 Proteine)/BC034767, MEIS1 (zeige MEIS1 Proteine), MAP2K5/SKOR1, and PTPRD (zeige PTPRD Proteine)

  7. Inhibitors of apoptosis proteins regulate myogenic differentiation by directly suppressing MEKK2 (zeige MAP3K2 Proteine)/3-MEK5-ERK5 (zeige MAPK7 Proteine) signaling.

  8. MiR (zeige MLXIP Proteine)-330-3p and MAP2K5 are potentially important contributors to mood and anxiety-related traits

  9. MEK5/ERK5 (zeige MAPK7 Proteine) signaling suppresses estrogen receptor (zeige ESR1 Proteine) expression and promotes hormone-independent tumorigenesis.

  10. Single nucleotide polymorphism in the MAP2K5 gene is associated with BMI and obesity.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) Interaktionspartner

  1. These results suggest that YAP (zeige YAP1 Proteine) promotes muscle differentiation by activating the Abl (zeige ABL1 Proteine)/Src (zeige SRC Proteine)/MEKK3 (zeige MAP3K3 Proteine)/MEK5/ERK5 (zeige MAPK7 Proteine) kinase cascade.

  2. MEK5 overexpression inhibits differentiation of osteoblasts.

  3. the MEK5-ERK5 (zeige MAPK7 Proteine) MAP kinase (zeige MAPK1 Proteine) signaling pathway has a critical role in BAFF (zeige TNFSF13B Proteine)-induced mature B cell survival and homeostatic maintenance of B2 cell numbers

  4. The MEK5/ERK5 (zeige MAPK7 Proteine) pathway also mediates FSS-induced Runx-2 (zeige RUNX2 Proteine) expression in osteoblast differentiation.

  5. finding suggested that REST promoted primordial germ cells survival via regulation of the Mek5 expression

  6. PB1 (zeige GPR97 Proteine) domain mediates the association of MEKK2 (zeige MAP3K2 Proteine) and MEKK3 (zeige MAP3K3 Proteine) with MEK5 and that the respective PB1 (zeige GPR97 Proteine) domains of these kinases are critical for regulation of the ERK5 (zeige MAPK7 Proteine) pathway.

  7. MEK5 is an activator of ERK5 (zeige MAPK7 Proteine) and an essential regulator of cell survival that is required for normal embryonic development

  8. the N terminus of MEK5alpha is critical for the specific organization of the components of the ERK5 (zeige MAPK7 Proteine) signaling pathway

  9. MEK5 and big MAP kinase 1 (BMK1 (zeige MAPK7 Proteine)) function downstream of MEKK3 (zeige MAP3K3 Proteine) in a signaling cascade that induces calcineurin (zeige PPP3CA Proteine) activity through phosphorylation of MCIP1 (zeige PPP3R1 Proteine)

  10. A noncanonical function of Map2k5 domain is decribed for coordinated erk5 (zeige MAPK7 Proteine) kinase and map2k7 (zeige MAP2K7 Proteine) signaling.

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) Interaktionspartner

  1. MKK4 (zeige MAP2K4 Proteine), MKK5, MKK7 (zeige MAP2K7 Proteine), and MKK9, are responsible for the activation of MPK3 (zeige MAPK3 Proteine) and MPK6 (zeige MAPK6 Proteine) by melatonin, indicating that melatonin-mediated innate immunity is triggered by MAPK (zeige MAPK1 Proteine) signaling through MKK4 (zeige MAP2K4 Proteine)/5/7/9-MPK3 (zeige MAPK3 Proteine)/6 cascades.

  2. Overexpression of MKK5 in wild-type plants enhanced their tolerance to salt treatments. Another kinase, MPK6 (zeige MAPK6 Proteine), was also involved in the MKK5-mediated iron superoxide dismutase (FSD) signalling pathway in salt stress.

  3. our data indicate that EDR1 physically associates with MKK4 (zeige MAP2K4 Proteine)/MKK5 and negatively regulates the MAPK (zeige MAPK1 Proteine) cascade to fine-tune plant innate immunity.

  4. Data indicate that in the MKK5-RNAi (RNA interference) lines, the induction of CSD1 and CSD2 (zeige TGFB1 Proteine) as well as the activation of MKK5 activity were completely arrested.

  5. Results suggest that the YDA-MKK4 (zeige MAP2K4 Proteine)/MKK5-MPK3 (zeige MAPK3 Proteine)/MPK6 (zeige MAPK6 Proteine) cascade functions downstream of the ER receptor in regulating localized cell proliferation, which further shapes the morphology of plant organs.

  6. MKK5 functions both in ozone-induced activation of MPK3 (zeige MAPK3 Proteine) and MPK6 (zeige MAPK6 Proteine) and in integrating reactive oxygen species homeostasis during ozone stress.

  7. MKK5 is a key regulator of stomatal development and patterning.

MAP2K5 Protein Überblick

Protein Überblick

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Alternative names and synonyms associated with MAP2K5

  • mitogen activated protein kinase kinase 5 (Map2k5)
  • mitogen-activated protein kinase kinase 5 (MAP2K5)
  • mitogen-activated protein kinase kinase 5 (Map2k5)
  • mitogen-activated protein kinase kinase 5 (map2k5)
  • mitogen-activated protein kinase kinase 5 (MKK5)
  • AI324775 Protein
  • AI428457 Protein
  • ATMAP2K_ALPHA Protein
  • ATMEK5 Protein
  • ATMKK5 Protein
  • fb73f02 Protein
  • HsT17454 Protein
  • MAP2K_A Protein
  • MAP kinase kinase 5 Protein
  • Mapkk5 Protein
  • MEK5 Protein
  • Prkmk5 Protein
  • wu:fb73f02 Protein
  • zgc:172137 Protein

Bezeichner auf Proteinebene für MAP2K5

MAP kinase kinase 5 , MAPK/ERK kinase 5 , MAPKK 5 , MEK 5 , dual specificity mitogen-activated protein kinase kinase 5 , mitogen-activated protein kinase kinase 5 , MAP kinase kinase MEK5b , MAPK/ERK kinese 5 , mitogen activated protein kinase kinase 5 , MEK5

29568 Rattus norvegicus
5607 Homo sapiens
609559 Canis lupus familiaris
23938 Mus musculus
100007679 Danio rerio
414694 Xenopus laevis
415557 Gallus gallus
100295732 Bos taurus
821676 Arabidopsis thaliana
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