Ninein (GSK3B Interacting Protein) Proteine (NIN)

Bezeichnung:
Ninein (GSK3B Interacting Protein) Proteine (NIN)
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Synonyme:
3110068G20Rik, AI385615, AU024711, mKIAA1565, ninein, SCKL7, si:ch211-282c13.6
alle Proteine anzeigen Gen GeneID UniProt
NIN 18080 Q61043
NIN 51199 Q8N4C6
NIN 299117  

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Weitere Proteine zu Ninein (GSK3B Interacting Protein) Interaktionspartnern

Mouse (Murine) Ninein (GSK3B Interacting Protein) (NIN) Interaktionspartner

  1. ninein is localized at the centrosome in undifferentiated neural precursors; but ninein was barely detected in migrating neurons, such as those in the intermediate layer of the cerebral cortex and the internal granular layer of the cerebellar cortex

Human Ninein (GSK3B Interacting Protein) (NIN) Interaktionspartner

  1. Ninein influences the rate of axonal growth and branching by affecting microtubule stability and dynamics.

  2. JAK2 Tyrosine Kinase (zeige JAK2 Proteine) phosphorylates centrosomal protein ninein, which negatively regulates it

  3. A Ninein (NIN) missense mutation identified in a family with spondyloepimetaphyseal dysplasia with joint laxity (leptodactylic type)-like phenotype.

  4. The role of hNinein isoform 6 expression in cell differentiation was assessed in BrdU-treated IMR-32 cells

  5. The prevalence of hNinein autoreactivity and its specificity in 22 rheumatoid arthritis and 32 systemic lupus erythematosus autoimmune disease sera.

  6. Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 (zeige ODF1 Proteine) and ninein.

  7. Two single nucleotide polymorphisms in the APC (zeige APC Proteine) and NIN loci were significantly associated with pancreatic cancer risk

  8. Ninein is essential for the reformation of specific aspects of the interphase centrosome architecture following mitosis as well as being required for the centrosome to function as a MTOC.

  9. ninein protein has two distinct subdomains required for centrosomal targeting and regulating signals in cell cycle

  10. Elevated ninein causes mislocalization of gamma-tubulin (zeige TUBG1 Proteine), recruiting it to ectopic (noncentrosomal) ninein-containing sites which are not active in nucleating microtubules, suggesting a regulatory role for ninein in microtubule nucleation.

Ninein (GSK3B Interacting Protein) (NIN) Protein Überblick

Protein Überblick

This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported.

Alternative names and synonyms associated with Ninein (GSK3B Interacting Protein) (NIN)

  • ninein (GSK3B interacting protein) (NIN)
  • ninein (GSK3B interacting protein) (nin)
  • ninein (lpg0126)
  • ninein (LPC_0146)
  • ninein (lpa_00185)
  • ninein (Nin)
  • ninein (GSK3B interacting protein) (Nin)
  • 3110068G20Rik Protein
  • AI385615 Protein
  • AU024711 Protein
  • mKIAA1565 Protein
  • ninein Protein
  • SCKL7 Protein
  • si:ch211-282c13.6 Protein

Bezeichner auf Proteinebene für NIN

ninein (GSK3B interacting protein) , ninein , ninein-like , glycogen synthase kinase 3 beta-interacting protein , hNinein , ninein centrosomal protein

GENE ID SPEZIES
480320 Canis lupus familiaris
510366 Bos taurus
100066583 Equus caballus
100157402 Sus scrofa
428928 Gallus gallus
571879 Danio rerio
709532 Macaca mulatta
733210 Xenopus laevis
779600 Xenopus (Silurana) tropicalis
3079450 Legionella pneumophila subsp. pneumophila str. Philadelphia 1
5181950 Legionella pneumophila str. Corby
9127893 Legionella pneumophila 2300/99 Alcoy
100078065 Ornithorhynchus anatinus
100351189 Oryctolagus cuniculus
100436699 Pongo abelii
100472191 Ailuropoda melanoleuca
100541919 Meleagris gallopavo
100604228 Nomascus leucogenys
18080 Mus musculus
51199 Homo sapiens
299117 Rattus norvegicus
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