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Kallikrein 14 Proteine (KLK14)

Bezeichnung:
Kallikrein 14 Proteine (KLK14)
Auf www.antikoerper-online.de finden Sie aktuell 5 Kallikrein 14 (KLK14) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Kallikrein 14 Antikörper (54) und Kallikrein 14 Kits (12) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 74 Kallikrein 14 Produkte verfügbar.
Synonyme:
GK14, KLK-L6
alle Proteine anzeigen Gen GeneID UniProt
KLK14 317653 Q8CGR5
Ratte KLK14 KLK14 308562  
KLK14 43847 Q9P0G3

Weitere Synonyme anzeigen

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Human Kallikrein 14 (KLK14) Interaktionspartner

  1. increased KLK14 activity could contribute at multiple levels to HGF (zeige HGF Proteine)/Met-mediated processes in prostate and other cancers

  2. KLK7 (zeige KLK7 Proteine) and KLK14 gene expression can be regarded as markers of poor prognosis for colorectal cancer patients with discriminating power between CC and adenoma patients.

  3. genetic variants in the KLK14 locus are associated with risk and/or aggressiveness of prostate cancer

  4. KLK14, acting via PAR-2 (zeige F2RL1 Proteine), represents an autocrine/paracrine regulator of colon tumorigenesis

  5. KLK8 (zeige KLK8 Proteine) and KLK14 can signal differentially via the PARs (zeige EPRS Proteine) to affect tissue function

  6. KLK14 gene expression could be evaluated as a putative independent diagnostic biomarker in breast tumour biopsies.

  7. The differences in the levels of KLK14 suggest that KLKs may aid in the differential diagnosis of salivary gland tumors. The coexpression of KLKs suggests their possible involvement in an enzymatic pathway activated in salivary gland.

  8. KLK14 overexpression was found to be a significant predictor of decreased disease-free survival and overall survival in breast cancer patients

  9. KLK14 expression upregulated in advanced and more aggressive prostate tumors; may play role in tumor spread and may be new marker for prostate cancer diagnosis and prognosis

  10. hK14 has dual activity, trypsin- and chymotrypsin-like, with a preference for cleavage after arginine residues

Kallikrein 14 (KLK14) Protein Überblick

Protein Überblick

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. An additional transcript variant has been described but its full length nature has not been determined.

Alternative names and synonyms associated with Kallikrein 14 (KLK14)

  • kallikrein related-peptidase 14 (Klk14)
  • kallikrein-related peptidase 14 (KLK14)
  • GK14 Protein
  • KLK-L6 Protein

Bezeichner auf Proteinebene für Kallikrein 14 Proteine (KLK14)

glandular kallikrein KLK14 , kallikrein 14 , kallikrein-14 , mGK14 , hK14 , kallikrein-like protein 6

GENE ID SPEZIES
317653 Mus musculus
308562 Rattus norvegicus
43847 Homo sapiens
484348 Canis lupus familiaris
613993 Bos taurus
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