CSF2RA Proteine (CSF2RA)

Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) Proteine (CSF2RA)
Auf www.antikoerper-online.de finden Sie aktuell 26 Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) Proteine von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CSF2RA Antikörper (189) und CSF2RA Kits (26) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 251 CSF2RA Produkte verfügbar.
alle Proteine anzeigen Gen GeneID UniProt
CSF2RA 1438 P15509
CSF2RA 12982 Q00941

Weitere Synonyme anzeigen

CSF2RA Proteine (CSF2RA) nach Spezies

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Am meisten referenzierte CSF2RA Proteine

  1. Human CSF2RA Protein expressed in HEK-293 - ABIN2666820 : Burmester, Feist, Sleeman, Wang, White, Magrini: Mavrilimumab, a human monoclonal antibody targeting GM-CSF receptor-α, in subjects with rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase I, first-in-human study. in Annals of the rheumatic diseases 2011 (PubMed)
    Zeige alle 6 Referenzen für 2666820

  2. Human CSF2RA Protein expressed in Human Cells - ABIN2003270 : McClure, Hercus, Cambareri, Woodcock, Bagley, Howlett, Lopez: Molecular assembly of the ternary granulocyte-macrophage colony-stimulating factor receptor complex. in Blood 2003 (PubMed)
    Zeige alle 5 Referenzen für 2003270

Weitere Proteine zu CSF2RA Interaktionspartnern

Cow (Bovine) Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) Interaktionspartner

Human Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) Interaktionspartner

  1. Our cohort broadens the spectrum of knowledge about the clinical variability and genotype-phenotype correlations of juvenile PAP (zeige REG3A Proteine), and illustrates the favorable outcome of WLL treatment in severely affected patients

  2. A possible relationship between dysfunction of the granulocyte-macrophage colony stimulating factor receptor, mapping to the pseudoautosomal X-Y region, may exist in myelodysplastic patients with initially lymphocytic Sweet syndrome.

  3. Studies indicate the action of GM-CSF (zeige CSF2 Proteine) can be inhibited by at least two approaches: inhibition by GM-CSF (zeige CSF2 Proteine) neutralising antibodies, or blockade of GM-CSF (zeige CSF2 Proteine) binding to its receptor by antibodies against the GM-CSF receptor alpha chain (zeige FCGRT Proteine) CSF2Ralpha.

  4. The GM-CSF (zeige CSF2 Proteine) Ralpha were ubiquitously but not uniformly expressed in neurons throughout the brain and downregulation in brain in patient with alzheimenr disease.

  5. This study reveals a novel functional role of clathrin-coated structure in GMR signaling and the oncogenesis of JAK2V617F.

  6. Identify defective expression and function of CD116 as a distinguishing feature of IBD and implicate an associated defect in innate immune responses toward granulocyte-macrophage colony-stimulating factor (zeige CSF2 Proteine).

  7. The expression rate of GM-CSFR in myelodysplastic syndrome patients was significantly higher than in aplastic anemia patients and controls.

  8. 67-kDa laminin receptor (zeige RPSA Proteine) expression influenced the characteristics of leukemia cells toward an aggressive phenotype and increased the number of granulocyte-macrophage colony-stimulating factor (zeige CSF2 Proteine) receptors

  9. Data show that Deletion of the Ig-like domain of GM-CSFRalpha abolished direct GM-CSF (zeige CSF2 Proteine) binding and decreased growth signalling in the presence of hbetac.

  10. soluble forms of the GM-CSF receptor alpha chain (zeige FCGRT Proteine) and beta chain were produced and a novel mechanism of receptor assembly was demonstrated

Mouse (Murine) Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) Interaktionspartner

  1. a STOP mutation in the GM-CSFRalpha chain, leading to a complete and specific deficiency in GM-CSF (zeige CSF2 Proteine) signaling, is reported.

  2. GM-CSFRalpha levels peaked between E13 and E15 in the brain.

  3. Loss of the CSF2RA gene may be a critical mutation explaining the high incidence of loss of sex chromosomes associated with the t(8;21)(q22;q22) translocation.

  4. ability to detect GM-CSF (zeige CSF2 Proteine) receptor expression in experimental studies should greatly facilitate the analysis of its role in immune pathologies[GM-CSF receptor alpha]

CSF2RA Protein Überblick

Protein Überblick

The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.

Alternative names and synonyms associated with CSF2RA

  • colony stimulating factor 2 receptor, alpha (CSF2RA)
  • colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA)
  • colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (Csf2ra)
  • CD116 Protein
  • CDw116 Protein
  • CSF2R Protein
  • CSF2RAX Protein
  • CSF2RAY Protein
  • CSF2RX Protein
  • CSF2RY Protein
  • Csfgmra Protein
  • GM-CSF-R-alpha Protein
  • GM-CSF-Ra Protein
  • GM-CSFR Protein
  • GMCSFR Protein
  • GMR Protein
  • SMDP4 Protein

Bezeichner auf Proteinebene für CSF2RA

CD116 antigen , GM-CSF receptor alpha subunit , GMCSFR-alpha , GMR-alpha , colony stimulating factor 2 receptor alpha subunit , granulocyte-macrophage colony-stimulating factor receptor alpha chain , granulocyte-macrophage colony-stimulating factor receptor subunit alpha , GM-CSF-R-alpha , GM-CSFRalpha , colony stimulating factor 2 receptor alpha chain

282207 Bos taurus
1438 Homo sapiens
12982 Mus musculus
Ausgewählte Anbieter für CSF2RA Proteine (CSF2RA)
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