CSF2RA Proteine (CSF2RA)

Bezeichnung:
Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) Proteine (CSF2RA)
Auf www.antikoerper-online.de finden Sie aktuell 26 Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) Proteine von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CSF2RA Antikörper (189) und CSF2RA Kits (26) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 251 CSF2RA Produkte verfügbar.
Synonyme:
CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, Csfgmra, GM-CSF-R-alpha, GM-CSF-Ra, GM-CSFR, GMCSFR, GMR, SMDP4
alle Proteine anzeigen Gen GeneID UniProt
CSF2RA 1438 P15509
CSF2RA 12982 Q00941

Weitere Synonyme anzeigen

CSF2RA Proteine (CSF2RA) nach Spezies

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Am meisten referenzierte CSF2RA Proteine

  1. Human CSF2RA Protein expressed in HEK-293 - ABIN2666820 : Burmester, Feist, Sleeman, Wang, White, Magrini: Mavrilimumab, a human monoclonal antibody targeting GM-CSF receptor-α, in subjects with rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase I, first-in-human study. in Annals of the rheumatic diseases 2011 (PubMed)
    Zeige alle 6 Referenzen für 2666820

  2. Human CSF2RA Protein expressed in Human Cells - ABIN2003270 : McClure, Hercus, Cambareri, Woodcock, Bagley, Howlett, Lopez: Molecular assembly of the ternary granulocyte-macrophage colony-stimulating factor receptor complex. in Blood 2003 (PubMed)
    Zeige alle 5 Referenzen für 2003270

Weitere Proteine zu CSF2RA Interaktionspartnern

Cow (Bovine) Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) Interaktionspartner

Human Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) Interaktionspartner

  1. Our cohort broadens the spectrum of knowledge about the clinical variability and genotype-phenotype correlations of juvenile PAP (zeige REG3A Proteine), and illustrates the favorable outcome of WLL treatment in severely affected patients

  2. A possible relationship between dysfunction of the granulocyte-macrophage colony stimulating factor receptor, mapping to the pseudoautosomal X-Y region, may exist in myelodysplastic patients with initially lymphocytic Sweet syndrome.

  3. Studies indicate the action of GM-CSF (zeige CSF2 Proteine) can be inhibited by at least two approaches: inhibition by GM-CSF (zeige CSF2 Proteine) neutralising antibodies, or blockade of GM-CSF (zeige CSF2 Proteine) binding to its receptor by antibodies against the GM-CSF receptor alpha chain (zeige FCGRT Proteine) CSF2Ralpha.

  4. The GM-CSF (zeige CSF2 Proteine) Ralpha were ubiquitously but not uniformly expressed in neurons throughout the brain and downregulation in brain in patient with alzheimenr disease.

  5. This study reveals a novel functional role of clathrin-coated structure in GMR signaling and the oncogenesis of JAK2V617F.

  6. Identify defective expression and function of CD116 as a distinguishing feature of IBD and implicate an associated defect in innate immune responses toward granulocyte-macrophage colony-stimulating factor (zeige CSF2 Proteine).

  7. The expression rate of GM-CSFR in myelodysplastic syndrome patients was significantly higher than in aplastic anemia patients and controls.

  8. 67-kDa laminin receptor (zeige RPSA Proteine) expression influenced the characteristics of leukemia cells toward an aggressive phenotype and increased the number of granulocyte-macrophage colony-stimulating factor (zeige CSF2 Proteine) receptors

  9. Data show that Deletion of the Ig-like domain of GM-CSFRalpha abolished direct GM-CSF (zeige CSF2 Proteine) binding and decreased growth signalling in the presence of hbetac.

  10. soluble forms of the GM-CSF receptor alpha chain (zeige FCGRT Proteine) and beta chain were produced and a novel mechanism of receptor assembly was demonstrated

Mouse (Murine) Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) Interaktionspartner

  1. a STOP mutation in the GM-CSFRalpha chain, leading to a complete and specific deficiency in GM-CSF (zeige CSF2 Proteine) signaling, is reported.

  2. GM-CSFRalpha levels peaked between E13 and E15 in the brain.

  3. Loss of the CSF2RA gene may be a critical mutation explaining the high incidence of loss of sex chromosomes associated with the t(8;21)(q22;q22) translocation.

  4. ability to detect GM-CSF (zeige CSF2 Proteine) receptor expression in experimental studies should greatly facilitate the analysis of its role in immune pathologies[GM-CSF receptor alpha]

CSF2RA Protein Überblick

Protein Überblick

The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.

Alternative names and synonyms associated with CSF2RA

  • colony stimulating factor 2 receptor, alpha (CSF2RA)
  • colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA)
  • colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (Csf2ra)
  • CD116 Protein
  • CDw116 Protein
  • CSF2R Protein
  • CSF2RAX Protein
  • CSF2RAY Protein
  • CSF2RX Protein
  • CSF2RY Protein
  • Csfgmra Protein
  • GM-CSF-R-alpha Protein
  • GM-CSF-Ra Protein
  • GM-CSFR Protein
  • GMCSFR Protein
  • GMR Protein
  • SMDP4 Protein

Bezeichner auf Proteinebene für CSF2RA

CD116 antigen , GM-CSF receptor alpha subunit , GMCSFR-alpha , GMR-alpha , colony stimulating factor 2 receptor alpha subunit , granulocyte-macrophage colony-stimulating factor receptor alpha chain , granulocyte-macrophage colony-stimulating factor receptor subunit alpha , GM-CSF-R-alpha , GM-CSFRalpha , colony stimulating factor 2 receptor alpha chain

GENE ID SPEZIES
282207 Bos taurus
1438 Homo sapiens
12982 Mus musculus
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