IRF1 Proteine (IRF1)

Auf www.antikoerper-online.de finden Sie aktuell 22 Interferon Regulatory Factor 1 (IRF1) Proteine von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IRF1 Antikörper (138) und IRF1 Kits (17) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 188 IRF1 Produkte verfügbar.
Synonyme:
AU020929, Irf-1, IRF1, irf11, MAR, zgc:103566, zgc:136945
alle Proteine anzeigen Gen GeneID UniProt
IRF1 3659 P10914
IRF1 16362 P15314
IRF1 24508 P23570

IRF1 Proteine (IRF1) nach Spezies

Weitere Proteine zu IRF1 Interaktionspartnern

Zebrafish Interferon Regulatory Factor 1 (IRF1) Interaktionspartner

  1. Following spring viremia of carp (zeige ANKRD1 Proteine) virus infection, DrIFNPhi1/3 and DrIRF1/3/7 transcripts are significantly induced in zebrafish tissues, which correlates with the replication of spring viremia of carp (zeige ANKRD1 Proteine) virus. data provide evidence that fish and mammals have evolved a similar IRF (zeige TRIM63 Proteine)-dependent regulatory mechanism fine-tuning IFN gene activation.

Human Interferon Regulatory Factor 1 (IRF1) Interaktionspartner

  1. IFN regulatory factor 1 effectively inhibits hepatitis E virus replication through the activation of the JAK (zeige JAK3 Proteine)-STAT (zeige STAT1 Proteine) pathway

  2. B. abortus lipoproteins via IL-6 (zeige IL6 Proteine) inhibit the expression of IFN regulatory factor 1 (IRF-1), a critical regulatory transcription factor for CIITA (zeige CIITA Proteine) induction.

  3. STAT1 (zeige STAT1 Proteine) and IRF1 collaborate to induce interferon-gamma (zeige IFNG Proteine) stimulated genes (ISGs), but the extent to which they act alone or together is unclear.This study provides strong evidence for widespread cooperation between STAT1 (zeige STAT1 Proteine) and IRF1 at ISGs, and suggests that in silico predictions reliably predict the effect of nucleotide variants on binding in vivo.

  4. aimed to determine the role of Treg cells and IRF-1 in MDS (zeige PAFAH1B1 Proteine)

  5. Tat (zeige TAT Proteine) exploited the cellular HDM2 (human double minute 2 protein (zeige MDM2 Proteine)) ubiquitin ligase to accelerate IRF-1 proteasome-mediated degradation, resulting in a quenching of IRF-1 transcriptional activity during HIV-1 infection.

  6. Leading to a STAT1 (zeige STAT1 Proteine)-IRF1 controlled upregulation of TLR3 (zeige TLR3 Proteine) expression in macrophages.

  7. Regulatory elements for both IRF-1 (-1019 to -1016) and CREB (zeige CREB1 Proteine) (-1198 to -1195), specific to the distal THBS1 (zeige THBS1 Proteine) promoter, were required for leptin (zeige LEP Proteine)-induced TSP-1 (zeige THBS1 Proteine) transcription.

  8. silencing of IL1B (zeige IL1B Proteine) plus dexamethasone-induced DUSP1 (zeige DUSP1 Proteine) significantly reduced IRF1 expression. IL1B (zeige IL1B Proteine)-induced expression of CXCL10 (zeige CXCL10 Proteine) was largely insensitive to dexamethasone, whereas other DUSP1 (zeige DUSP1 Proteine)-enhanced, IRF1-dependent mRNAs showed various degrees of repression.

  9. Inflammation-driven IRF1 and NF-kappaB (zeige NFKB1 Proteine) activity promotes ERVK reactivation.

  10. MiR (zeige MLXIP Proteine)-23a downregulates the expression of IRF-1 in HCC (zeige FAM126A Proteine) cells.

Pig (Porcine) Interferon Regulatory Factor 1 (IRF1) Interaktionspartner

  1. Given these results, porcine IRF1 plays potential roles in cellular antiviral responses against swine viruses.

  2. In a healthy swine model, elevated levels of endothelial IRF-1 were also observed within atherosusceptible regions of the aorta by Western blot analysis and immunohistochemistry, implicating arterial hemodynamics in the regulation of IRF-1 expression.

  3. The results suggested that the porcine IRF1 gene is strong candidate gene for these immune traits in pig.

Mouse (Murine) Interferon Regulatory Factor 1 (IRF1) Interaktionspartner

  1. Our studies uncovered the critical role of two transcription factors, IRF1 and BATF, in preparing the chromatin landscape for induction of the Tr1 gene network in response to IL-27 signaling, where BATF acted as a pioneer factor and prepared the genomic landscape for the binding of additional transcription factors that define the Tr1 lineage.

  2. IRF-1 and interferon-alpha (zeige IFNA Proteine) with interferon-beta (zeige IFNB1 Proteine) cooperate to control acute gammaherpesvirus infection.

  3. this study shows that binding motifs for the transcription factors STAT1 (zeige STAT1 Proteine) and IRF1 are associated with robust and IL-4 (zeige IL4 Proteine)-resistant responses to IFN-gamma (zeige IFNG Proteine) in macrophages

  4. 5AZ had a protective effect after MI by potentiation of IRF1 sumoylation and is suggested as a novel therapeutic intervention for cardiac repair.

  5. direct the expression of a set of genes, the IRF8 (zeige IRF8 Proteine)/IRF1 regulome, that play critical roles in host inflammatory and antimicrobial defenses in mouse models of neuroinflammation and of pulmonary tuberculosis, respectively

  6. couples synthesis of miR (zeige MLXIP Proteine)-342-5p to the antiviral interferon (zeige IFNA Proteine) response

  7. The gammaherpesvirus-driven germinal center expansion was exaggerated and lost its transient nature in the absence of interferon-regulatory factor 1 (IRF-1), a transcription factor with antiviral and tumor suppressor functions.

  8. IRF1 is required for IRF8 (zeige IRF8 Proteine)-induced gene expression in microglia.

  9. in addition to regulating the enterocyte metabolic switch, Blimp1 functions as a gatekeeper in opposition to Irf1 to prevent premature activation of the MHC class I pathway in villus epithelium to maintain tolerance in the neonatal intestine.

  10. Although treatment with IFN-gamma (zeige IFNG Proteine) strongly induced the activation of STAT1 (zeige STAT1 Proteine) as a transcriptional activator, its target molecule, IRF1, was not clearly produced in Lmp2 (zeige PSMB9 Proteine)-deficient uterine smooth muscle cells.

IRF1 Protein Überblick

Protein Überblick

IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

Alternative names and synonyms associated with IRF1

  • interferon regulatory factor 1 (IRF1)
  • interferon regulatory factor 1a (irf1a)
  • interferon regulatory factor 1b (irf1b)
  • interferon regulatory factor 1 (Irf1)
  • AU020929 Protein
  • Irf-1 Protein
  • IRF1 Protein
  • irf11 Protein
  • MAR Protein
  • zgc:103566 Protein
  • zgc:136945 Protein

Bezeichner auf Proteinebene für IRF1

interferon regulatory factor 1 , interferon regulatory factor 11 , IRF-1 , interferon responsive factor 1

GENE ID SPEZIES
443136 Ovis aries
678604 Danio rerio
792160 Danio rerio
396384 Gallus gallus
3659 Homo sapiens
481500 Canis lupus familiaris
396611 Sus scrofa
789216 Bos taurus
16362 Mus musculus
24508 Rattus norvegicus
100328724 Oryctolagus cuniculus
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