YWHAZ Proteine (YWHAZ)

Auf www.antikoerper-online.de finden Sie aktuell 36 Phospholipase A2 (YWHAZ) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen YWHAZ Antikörper (102) und YWHAZ Kits (18) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 163 YWHAZ Produkte verfügbar.
Synonyme:
bvPLA2, C133, CG4346, Dmel\\CG42237, Dmel_CG4346, GB13351, PLA2, Pla2a, PLA2G1B, PPLA2, sPLA(2)-IB, sPLA2IB
alle Proteine anzeigen Gen GeneID UniProt
YWHAZ 5319 P04054
Maus YWHAZ YWHAZ 18778 Q9Z0Y2
Ratte YWHAZ YWHAZ 29526 P04055

YWHAZ Proteine (YWHAZ) nach Spezies

Weitere Proteine zu YWHAZ Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Phospholipase A2 (YWHAZ) Interaktionspartner

Human Phospholipase A2 (YWHAZ) Interaktionspartner

  1. The sPLA2 (zeige PLA2G2A Proteine) IB-PLA2R (zeige PLA2R1 Proteine) interaction stimulated podocyte apoptosis through activating ERK1/2 and cPLA2alpha (zeige PLA2G4A Proteine) and through increasing the podocyte AA content

  2. TNF-alpha (zeige TNF Proteine)-induced cPLA2 (zeige PLA2G4A Proteine) expression and PGE2 release were mediated through a Jak2 (zeige JAK2 Proteine)/PDGFR (zeige PDGFRB Proteine)/PI3K (zeige PIK3CA Proteine)/Akt (zeige AKT1 Proteine)/p42/p44 (zeige PSMC6 Proteine) MAPK (zeige MAPK3 Proteine)/Elk-1 (zeige ELK1 Proteine) pathway in human lung epithelial cells.

  3. stimulation of three isoforms of PLA2 by thapsigargin liberates free AA that, in turn, induces capacitative calcium influx in human T-cells

  4. results indicate a selective sorting of a cell-derived cPLA2 (zeige PLA2G4A Proteine) during human cytomegalovirus maturation, which is further required for infectivity

  5. Group IB phospholipase A2 (PLA2G1B) stimulates leukotriene B4 (LTB4 (zeige PTGR1 Proteine)) production in the absence of cytochalasin B in human neutrophils.

  6. Here, we report sPLA2 (zeige PLA2G2A Proteine)-IB in rat and human brain as well as in neurons in primary culture. The distribution of sPLA2 (zeige PLA2G2A Proteine)-IB seems to be mainly neuronal, with the highest abundance occurring in the cerebral cortex and hippocampus.

  7. a critical regulatory role of arachidonate reacylation that limits leukotriene biosynthesis in concert with 5-lipoxygenase (zeige ALOX5 Proteine) and cytosolic phospholipase A (zeige HRASLS Proteine)(2)alpha activation

  8. Results describe the structural basis for bile salt inhibition of pancreatic phospholipase A2.

  9. MMP-2 (zeige MMP2 Proteine)/9 production is regulated by sPLA2 (zeige PLA2G2A Proteine)-IB acting as a receptor ligand to activate cPLA2 (zeige PLA2G4A Proteine)

Pig (Porcine) Phospholipase A2 (YWHAZ) Interaktionspartner

  1. Equilibrium unfolding of porcine pancreatic phospholipase A2 was monitored using multiple approaches. An unusually broad unfolding transition at remarkably high denaturant concentration was observed.

  2. Porcine group IB secretory phospholipase A2 (PLA2G1B) stimulates the expression and secretion of CXC chemokine (zeige CXCL12 Proteine) ligand 8 (zeige CCL8 Proteine) (CXCL8 (zeige IL8 Proteine)) in human neutrophils without affecting other proinflammatory cytokines.

  3. Porcine pancreatic PLA(2) shows a long lag (zeige STMN1 Proteine) phase of several hours during which the enzyme binds to the bilayer surface, but only 5+/-3% of the lipids react before the onset of rapid hydrolysis.

  4. Results describe the structural basis for bile salt inhibition of pancreatic phospholipase A2.

  5. MMP-2 (zeige MMP2 Proteine)/9 production is regulated by sPLA2 (zeige PLA2G2A Proteine)-IB acting as a receptor ligand to activate cPLA2 (zeige PLA2G4A Proteine)

  6. Results show that the decylsulfate epitope for the successive E i (#) complexes increasingly resembles the micellar complex formed by the binding of PLA2 to preformed micelles.

  7. An increased sPLA(2 (zeige PLA2G2A Proteine)) activity and a reduced inhibition may play an important role in the pathogenesis of ischemia-reperfusion injury of non-heart-beating donor liver grafts.

  8. Interfacial activation of pig pancreatic IB phospholipase A (zeige HRASLS Proteine)(2) (PLA2) is modeled in terms of the three discrete premicellar complexes (E(i)(#), i = 1, 2, or 3) consecutively formed by the cooperative binding of a monodisperse amphiphile to the i-face

Cow (Bovine) Phospholipase A2 (YWHAZ) Interaktionspartner

  1. Phospholipase A2 isoforms are differentially regulated; they selectively participate in retinal signaling in an experimental model of age-related macular degeneration.

  2. results suggest the hydrophobic surfactant protein, SP-B, protects alveolar surfactant phospholiopids from hydrolysis mediated by multiple sPLA(2 (zeige PLA2G2A Proteine)) in both vesicles (alveolar subphase) and monomolecular films (air-liquid interface)

  3. crystal structure of the triple mutant pancreatic phospholipase A2 with calcium.

  4. NMR characterization of a unique low-barrier hydrogen bond between an active site residue from the enzyme and a bound inhibitor: the complex between secreted phospholipase A (zeige HRASLS Proteine)(2) (sPLA(2 (zeige PLA2G2A Proteine)), from bovine pancreas) and a transition-state analog inhibitor HK32

  5. The final protein model consists of 123 amino-acid residues, two calcium ions, one chloride ion, 243 water molecules and six 2 (zeige SIX2 Proteine)-methyl-2,4-pentanediol molecules.

  6. The crystal structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2 complexed with an organic molecule, p-methoxybenzoic acid (anisic acid), is reported.

  7. The quadruple mutant of phospholipase A2 has monoclinic or trigonal crystal structures and results suggested evidence for the involvement of the second calcium and surface loop in interfacial binding.

Mouse (Murine) Phospholipase A2 (YWHAZ) Interaktionspartner

  1. Pla2g1b inactivation suppressed diet-induced body weight gain and reduced diabetes and atherosclerosis in LDL receptor (zeige LDLR Proteine)-deficient mice.

  2. inhibition of Pla2g1b protects against diet-induced hyperlipidemia

  3. Lysophospholipids produced by Pla2g1b hydrolysis suppress hepatic fat utilization and down-regulate energy expenditure, preventing metabolically beneficial adaptation to a high-fat diet exposure in promoting diet-induced obesity and type 2 diabetes.

  4. sPLA2IB has a role in promoting MMP-2 (zeige MMP2 Proteine) mediated cell migration via the phosphatidylinositol 3-kinase and Akt (zeige AKT1 Proteine) pathway

  5. Elevating plasma lysophospholipid levels in Pla2g1b deficient mice via intraperitoneal injection resulted in glucose intolerance.

  6. pro-inflammatory effects of Ps. aeruginosa involve release of an sPLA2 of epithelial origin that, in part, via distinct signalling molecules, transactivates the ABCA1 gene, leading to export of phospholipid.

Horse (Equine) Phospholipase A2 (YWHAZ) Interaktionspartner

  1. The results indicate that PLA2 activity in equine endometrium changes with the stage of the oestrous cycle and thus may be influenced by systemic hormone concentrations.

  2. During pregnancy, PLA2 expression may be sufficient to initiate the cascade for prostaglandin f2alpha secretion and does not play a direct role in maternal recognition of pregnancy.

YWHAZ Protein Überblick

Protein Überblick

Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986

Alternative names and synonyms associated with YWHAZ

  • CG42237 gene product from transcript CG42237-RA (CG42237)
  • phospholipase A2 (PLA2)
  • phospholipase A2 (Pla2)
  • phospholipase A2, group IB (pancreas) (PLA2G1B)
  • phospholipase A2, group IB (pancreas) (Pla2g1b)
  • phospholipase A2, group IB, pancreas (Pla2g1b)
  • phospholipase A2, group IVA (cytosolic, calcium-dependent) (PLA2G4A)
  • bvPLA2 Protein
  • C133 Protein
  • CG4346 Protein
  • Dmel\\CG42237 Protein
  • Dmel_CG4346 Protein
  • GB13351 Protein
  • PLA2 Protein
  • Pla2a Protein
  • PLA2G1B Protein
  • PPLA2 Protein
  • sPLA(2)-IB Protein
  • sPLA2IB Protein

Bezeichner auf Proteinebene für Phospholipase A2 Proteine (YWHAZ)

CG42237-PA , phospholipase A2 , allergen Api m 1 , allergen Api m I , phosphatidylcholine 2-acylhydrolase , phosphatidylcholine 2-acylhydrolase 1B , group IB phospholipase A2 , group IB secretory phospholipase A(2) , phospholipase A2, major isoenzyme , Group IB phospholipase A2 , Phosphatidylcholine 2-acylhydrolase 1B , phospholipase A2, group IB, pancreas , PLA2-Ib , phospholipase A2 group IB , phospholipase A2, group 1B , cPLA2 , cytosolic phospholipase A2 , phospholipase A2 group IVA , phospholipase A2, group IB (pancreas)

GENE ID SPEZIES
32261 Drosophila melanogaster
5725622 Chlamydomonas reinhardtii
100631065 Bombus terrestris
406141 Apis mellifera
5319 Homo sapiens
404011 Canis lupus familiaris
445525 Sus scrofa
100732984 Cavia porcellus
282457 Bos taurus
101117700 Ovis aries
18778 Mus musculus
29526 Rattus norvegicus
100033889 Equus caballus
Ausgewählte Anbieter für YWHAZ Proteine (YWHAZ)
Haben Sie etwas anderes gesucht?