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Transthyretin Proteine (TTR)

Bezeichnung:
Transthyretin Proteine (TTR)
Auf www.antikoerper-online.de finden Sie aktuell 62 Transthyretin (TTR) Proteine von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Transthyretin Antikörper (307) und Transthyretin Kits (72) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 449 Transthyretin Produkte verfügbar.
Synonyme:
AA408768, AI787086, CTS, CTS1, D17860, HsT2651, LOC100226992, Lr1, PALB, Prealbumin, Tbpa, TTR, xTTR, zgc:103583
alle Proteine anzeigen Gen GeneID UniProt
TTR 7276 P02766
TTR 22139 P07309
TTR 24856 P02767

Weitere Synonyme anzeigen

Transthyretin Proteine (TTR) nach Spezies

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Am meisten referenzierte Transthyretin Proteine

  1. Human TTR Protein expressed in HEK-293 Cells - ABIN2181876 : Herbert, Wilcox, Pham, Fremeau, Zeviani, Dwork, Soprano, Makover, Goodman, Zimmerman: Transthyretin: a choroid plexus-specific transport protein in human brain. The 1986 S. Weir Mitchell award. in Neurology 1986 (PubMed)
    Zeige alle 5 Referenzen für ABIN2181876

  2. Human TTR Protein expressed in Human Cells - ABIN2005037 : Naylor, Newcomer: The structure of human retinol-binding protein (RBP) with its carrier protein transthyretin reveals an interaction with the carboxy terminus of RBP. in Biochemistry 1999 (PubMed)
    Zeige alle 5 Referenzen für ABIN2005037

Weitere Proteine zu Transthyretin Interaktionspartnern

Human Transthyretin (TTR) Interaktionspartner

  1. TTR V30M aggregates and autophagy impairment are associated with Transthyretin amyloidoses .

  2. In Afro-Caribbean patients living in London, ATTR V122I is an underappreciated cause of heart failure, and cardiomyopathy is often misattributed to hypertension.

  3. Val122Ile is the most common transthyretin mutation, and neurologic phenotypic expression differs between wild-type disease and Val122Ile, but survival from enrollment in THAOS does not.

  4. In the bound state, the Hsp90 (zeige HSP90 Proteine) dimer predominantly populates an open conformation, and transthyretin retains its globular structure.

  5. findings show that, at physiologically-relevant protein concentrations, the refolding pathways of WT-TTR and amyloidogenic variant V30M-TTR follow a common mechanism observed among other tetrameric proteins; although sharing the same kinetic mechanism, V30M-TTR refolds at a slower rate than WT-TTR, a feature that may favor the formation of transient species leading to kinetic partition into amyloidogenic pathways

  6. This study reports the discovery of a TTR mutant, N98A, that was more effective at inhibiting ABETA (zeige APP Proteine) aggregation than wild-type (WT) TTR, although N98A and WT bound ABETA (zeige APP Proteine) equally.

  7. Results provide evidence that TTR acts as a carrier of Abeta (zeige APP Proteine) at the blood-brain-barrier and liver, using LRP1 (zeige LRP1 Proteine).

  8. The study reports a Japanese family with hereditary ATTR amyloidosis with the TTR G47R mutation in which one family member developed the disease at the age of 13.

  9. a point mutation was identified in the upstream regulatory region of the TTR gene in a Han Chinese family with familial vitreous amyloidosis.

  10. Data indicte that the use of polyethylene glycol (PEG (zeige PAEP Proteine)) to crystallize transthyretin (TTR complexes have resulted in a new trigonal polymorph with two tetramers in the asymmetric unit.

Mouse (Murine) Transthyretin (TTR) Interaktionspartner

  1. TTR mediated transport of thyroxine represents a survival mechanism necessary for the myogenic program.

  2. provide evidence of a new role of Transthyretin as a transcription inducer of insulin (zeige INS Proteine)-like growth factor receptor (zeige RYK Proteine) I in central nervous system, unveiling a new role in neuroprotection

  3. data also indicate that it is unlikely that the behaviors seen in Ttr(-/-) mice are related to its function

  4. Native transthyretin inhibits all preeclampsia-like features in the humanized mouse model.

  5. Transthyretin silencing (TTRkd) significantly reduced myogenin (zeige MYOG Proteine) expression.

  6. Amyloid fibrils formed by a mutant form of TTR, A25T, activate microglia, leading to the secretion of tumor necrosis factor-alpha (TNF-alpha (zeige TNF Proteine)), interleukin-6 (IL-6 (zeige IL6 Proteine)) and nitric oxide.

  7. Hsf-1 (zeige HSF1 Proteine) affects podocyte markers NPHS1 (zeige NPHS1 Proteine), NPHS2 and WT1 (zeige WT1 Proteine) in a transgenic mouse model of TTRVal30Met-related amyloidosis.

  8. Fibroblasts endocytose and degrade transthyretin aggregates in transthyretin-related amyloidosis.

  9. Increased degradation of 14-3-3zeta (zeige YWHAZ Proteine) in lysosomes in the absence of TTR, increasing autophagy.

  10. our data demonstrate that the increased expression of Ttr in ob/ob mice does not cause (but rather attenuates) their phenotypic abnormalities.

Pig (Porcine) Transthyretin (TTR) Interaktionspartner

  1. The rank order potency of the chemicals tested for the displacement of [125I]TIP from TTR was TIP > ioxynil > pentachlorophenol, T4, and retinoic acid > tetrabromobisphenol A, diethylstilbestrol, and T3.

  2. This study suggested closer links between the release of haptoglobin (zeige HP Proteine), Pig-MAP and monocytes compared to the release of AGP, SAA (zeige SAA1 Proteine) and transthyretin.

Xenopus laevis Transthyretin (TTR) Interaktionspartner

  1. Study determined the genomic structure of the Xenopus laevis TTR gene including 5'-flanking regions, and examined TTR expression patterns in several tissues; coding regions of xTTR gene was separated into 4 exons by 3 introns and these numbers were in agreement with those determined for the human, mouse, and rat genes

Transthyretin (TTR) Protein Überblick

Protein Überblick

This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein\; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported\; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

Alternative names and synonyms associated with Transthyretin (TTR)

  • transthyretin (prealbumin, amyloidosis type I) (ttr)
  • transthyretin (TTR)
  • transthyretin (vpb38)
  • transthyretin (Mrad2831_1253)
  • Transthyretin (Caci_4246)
  • transthyretin (prealbumin, amyloidosis type 1) (ttr)
  • transthyretin (LOC100226992)
  • transthyretin (Ttr)
  • transthyretin (LOC100347317)
  • transthyretin (ttr)
  • AA408768 Protein
  • AI787086 Protein
  • CTS Protein
  • CTS1 Protein
  • D17860 Protein
  • HsT2651 Protein
  • LOC100226992 Protein
  • Lr1 Protein
  • PALB Protein
  • Prealbumin Protein
  • Tbpa Protein
  • TTR Protein
  • xTTR Protein
  • zgc:103583 Protein

Bezeichner auf Proteinebene für Transthyretin Proteine (TTR)

transthyretin , transthyretin (prealbumin, amyloidosis type I) , Transthyretin , transthyretin (prealbumin, amyloidosis type 1) , ATTR , carpal tunnel syndrome 1 , prealbumin, amyloidosis type I , thyroxine-binding prealbumin , TBPA , prealbumin

GENE ID SPEZIES
449556 Danio rerio
705943 Macaca mulatta
5383938 Vibrio vulnificus
6137271 Methylobacterium radiotolerans JCM 2831
8335600 Catenulispora acidiphila DSM 44928
100101780 Xenopus (Silurana) tropicalis
100226992 Taeniopygia guttata
7276 Homo sapiens
22139 Mus musculus
24856 Rattus norvegicus
396277 Gallus gallus
280948 Bos taurus
493188 Pan troglodytes
443389 Ovis aries
100347317 Oryctolagus cuniculus
100735950 Cavia porcellus
397419 Sus scrofa
480167 Canis lupus familiaris
397787 Xenopus laevis
100174094 Pongo abelii
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