anti-RHBDF2 (RHBDF2) Antikörper

Bezeichnung:
anti-Rhomboid 5 Homolog 2 (Drosophila) Antikörper (RHBDF2)
Auf www.antikoerper-online.de finden Sie aktuell 21 Rhomboid 5 Homolog 2 (Drosophila) (RHBDF2) Antikörper von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RHBDF2 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 32 RHBDF2 Produkte verfügbar.
Synonyme:
4732465I17Rik, RHBDL5, Rhbdl6, TOC
Alle Antikörper anzeigen Gen GeneID UniProt
RHBDF2 79651 Q6PJF5
RHBDF2 217344 Q80WQ6

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-RHBDF2 (RHBDF2) Antikörper

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anti-Human RHBDF2 Antikörper:

anti-Mouse (Murine) RHBDF2 Antikörper:

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Weitere Antikörper gegen RHBDF2 Interaktionspartner

Human Rhomboid 5 Homolog 2 (Drosophila) (RHBDF2) Interaktionspartner

  1. results explain how loss of the amino terminus in iRhom1 (zeige RHBDF1 Antikörper) and iRhom2 impairs TNF (zeige TNF Antikörper) signaling, despite enhancing ADAM17 (zeige ADAM17 Antikörper) activity

  2. Tylosis with oesophageal cancer-associated mutations in iRHOM2 cause an increase in the maturation and activity of ADAM17 (zeige ADAM17 Antikörper) in epidermal keratinocytes.

  3. Our analyses suggest that these DNA methylation (zeige HELLS Antikörper) changes may have a role in the onset of Alzheimer disease given that we observed them in presymptomatic subjects and that six of the validated genes connect to a known susceptibility gene network.

  4. RHBDF2 and CYGB (zeige CYGB Antikörper) may play distinctive roles in ovarian cancer and could be added to the growing roster of chromosome 17 genes implicated in this disease.

  5. The distribution of RHBDF2 in tylotic skin is altered in comparison with that in normal skin.

Mouse (Murine) Rhomboid 5 Homolog 2 (Drosophila) (RHBDF2) Interaktionspartner

  1. baseline expression of genes acting within the NRF2 (zeige NFE2L2 Antikörper) anti-oxidative pathway, followed by gene alterations associated with the integrin receptor aggregation pathway and the FcgammaR-mediated phagocytosis pathway, contribute to accelerated wound healing

  2. the critical role of the transmembrane domains of ADAM17 (zeige ADAM17 Antikörper) and Rhbdf2 in the regulation of the ADAM17 (zeige ADAM17 Antikörper) and EGFR (zeige EGFR Antikörper), and ADAM17 (zeige ADAM17 Antikörper) and TNFalpha (zeige TNF Antikörper) signaling pathways, was examined.

  3. this study shows that the iRhom2/ADAM17 (zeige ADAM17 Antikörper) pathway plays an important role in regulating CSF1R (zeige CSF1R Antikörper) expression in the myeloid cell compartment at steady state, and in modulating development of monocytes/macrophages during their repopulation

  4. this study shows that iRhom2-deficient mice were more susceptible to lethal herpes simplex virus type 1 infection, and that iRhom2 is essential for STING activity, as it regulates TRAPbeta (zeige SSR2 Antikörper)-mediated translocation and EIF3S5 (zeige EIF3F Antikörper)-mediated deubiquitination of STING

  5. This study identifies iRhom2 as a novel regulator for determination of keratinocyte lineages.

  6. IRhom2 may be a promising therapeutic target for LPS (zeige TLR4 Antikörper)-induced cardiac injury.

  7. iRhom2 is required for the maturation of TACE (zeige ADAM17 Antikörper) and hair follicle differentiation.

  8. a principal function of iRhoms1/2 during mouse development is to regulate ADAM17 (zeige ADAM17 Antikörper)-dependent EGFR (zeige EGFR Antikörper) signaling

  9. Rhbdf2 mutations increase its protein stability and drive EGFR (zeige EGFR Antikörper) hyperactivation through enhanced secretion of amphiregulin (zeige AREG Antikörper).

  10. findings uncover functions for iRhom2 in the regulation of EGFR (zeige EGFR Antikörper) signaling and in controlling the activation and substrate selectivity of ADAM17 (zeige ADAM17 Antikörper)-dependent shedding events

RHBDF2 Antigen-Profil

Beschreibung des Gens

Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity).

Alternative names and synonyms associated with RHBDF2

  • rhomboid 5 homolog 2 (Drosophila) (RHBDF2) Antikörper
  • rhomboid 5 homolog 2 (Drosophila) (Rhbdf2) Antikörper
  • 4732465I17Rik Antikörper
  • RHBDL5 Antikörper
  • Rhbdl6 Antikörper
  • TOC Antikörper

Bezeichner auf Proteinebene für RHBDF2

iRhom2 , inactive rhomboid protein 2 , rhomboid family member 2 , rhomboid veinlet-like protein 5 , rhomboid veinlet-like protein 6 , rhomboid, veinlet-like 6 , rhomboid-like protein 6 , rhomboid-related protein , Rhomboid family member 2 , rhomboid veinlet-like 6

GENE ID SPEZIES
79651 Homo sapiens
217344 Mus musculus
483332 Canis lupus familiaris
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