Versican Proteine (Vcan)

Versican Proteine (Vcan)
Auf finden Sie aktuell 5 Versican (Vcan) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Versican Antikörper (119) und Versican Kits (39) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 164 Versican Produkte verfügbar.
5430420N07Rik, 9430051N09, br146, Cspg2, cspg2a, cspg2b, dcan, DPEAAE, ERVR, fb99b07, GHAP, hdf, NG2, PG-M, PG-M(V0), PG-M(V1), sb:cb63, VCAN, versican, WGN, WGN1, wu:fb99b07, Xversican
alle Proteine anzeigen Gen GeneID UniProt
Vcan 1462 P13611
Vcan 13003  
Ratte Vcan Vcan 114122 Q9ERB4

Weitere Synonyme anzeigen

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Weitere Proteine zu Versican Interaktionspartnern

Zebrafish Versican (Vcan) Interaktionspartner

  1. The isolation and characterization of a cDNA encoding zebrafish dermacan, a novel member of hyaluronan (HA)-binding proteoglycans, which was termed after its characteristic expression in the zebrafish dermal bones.

Human Versican (Vcan) Interaktionspartner

  1. Versican V0 and V1 isoforms were upregulated in the uterine leiomyomas of symptomatic versus asymptomatic women. Abundant cleaved versican was detected in leiomyoma and myometrium, as well as in myometrial and leiomyoma cell lines. VCAN siRNA did not effect cell proliferation, apoptosis, or smooth muscle markers, but reduced ESR1 (zeige ESR1 Proteine) and PR-A (zeige PGR Proteine) expression.

  2. Lumican (zeige LUM Proteine) and versican protein expression are associated with colorectal adenoma-to-carcinoma progression

  3. Removal or knockdown of versican may be a possible therapeutic strategy for increasing deposition of insoluble elastin (zeige ELN Proteine) and stimulating repair of elastic fibers in COPD (zeige ARCN1 Proteine) lung.

  4. human myeloma tumors displaying CD8 (zeige CD8A Proteine)(+) infiltration/aggregates underwent VCAN proteolysis at a site predicted to generate a glycosaminoglycan-bereft N-terminal fragment.

  5. versican decreases in follicular dermal papilla as an aging-associated change of human hair follicles

  6. Data indicate that serum versican levels were significantly decreased in polycystic ovary syndrome (PCOS) patients, and that serum ADAMTS-1 (zeige ADAMTS1 Proteine) (a disintegrin and metalloproteinase with thrombospondin motif-1) and versican levels were significantly and positively correlated with each other.

  7. the G1 domain of versican can regulate the organization of pericellular hyaluronan and affect phenotype of cultured human dermal fibroblasts

  8. Gene expression levels of three randomly selected DEGs (zeige DEGS1 Proteine), VCAN, COL5A1 and KCNJ16 (zeige KCNJ16 Proteine), were examined using RT-PCR in 10 ATC (zeige SRPK1 Proteine) samples.. angiogenesis was activated by the high expression of CTHRC1 (zeige CTHRC1 Proteine), VCAN and POSTN (zeige POSTN Proteine), providing necessary nutrition for tumor cells

  9. Results highlight an important role for versican in regulating the expression and assembly of elastin (zeige ELN Proteine) and the phenotype of leiomyosarcoma cells.

  10. Versican localizes to the nucleus in proliferating mesenchymal cells and suggest role in mitotic spindle organization during cell division.

Mouse (Murine) Versican (Vcan) Interaktionspartner

  1. Loss of Versican is associated with reduced Lung Inflammatory Response.

  2. Results highlight an important role for versican in regulating the expression and assembly of elastin (zeige ELN Proteine) and the phenotype of leiomyosarcoma cells.

  3. Versican localizes to the nucleus in proliferating mesenchymal cells and suggest role in mitotic spindle organization during cell division.

  4. Pelvic irradiation increases versican expression in bladder and rectum.

  5. Versican V1 overexpression induces a myofibroblast-like phenotype in cultured fibroblasts.

  6. The data suggest that versican plays an important role in fundamental, overlapping cellular processes in lung development and infection.

  7. Our results show that versican released from glioma promotes tumor expansion through glioma-associated microglial/macrophage TLR2 signaling and subsequent expression of MT1-MMP (zeige MMP14 Proteine).

  8. Arylsulfatase B (zeige ARSB Proteine) regulates versican expression by galectin-3 (zeige LGALS3 Proteine) and AP-1 (zeige JUN Proteine) mediated transcriptional effects.

  9. Versican regulates the growth of leiomyosarcoma tumors.

  10. expression of Vcan mRNA splice form proteins alters heart morphology and cellular protein profiles

Cow (Bovine) Versican (Vcan) Interaktionspartner

  1. Data show that expression of mRNAs for aggrecan (zeige ACAN Proteine), collagen type II, and versican were significantly effected by the intervention.

  2. Data show that biglycan (zeige BGN Proteine), collagen type I, collagen type II, decorin (zeige DCN Proteine), and versican were significantly affected by vibration duration, frequency, and amplitude.

Pig (Porcine) Versican (Vcan) Interaktionspartner

  1. The relationship between hyaluronan synthesis and levels of versican, fibronectin (zeige FN1 Proteine) and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.

Versican (Vcan) Protein Überblick

Protein Überblick

This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Versican (Vcan)

  • versican a (vcana)
  • versican b (vcanb)
  • versican (VCAN)
  • versican (vcan)
  • versican (Vcan)
  • versican (LOC100008666)
  • 5430420N07Rik Protein
  • 9430051N09 Protein
  • br146 Protein
  • Cspg2 Protein
  • cspg2a Protein
  • cspg2b Protein
  • dcan Protein
  • DPEAAE Protein
  • ERVR Protein
  • fb99b07 Protein
  • GHAP Protein
  • hdf Protein
  • NG2 Protein
  • PG-M Protein
  • PG-M(V0) Protein
  • PG-M(V1) Protein
  • sb:cb63 Protein
  • VCAN Protein
  • versican Protein
  • WGN Protein
  • WGN1 Protein
  • wu:fb99b07 Protein
  • Xversican Protein

Bezeichner auf Proteinebene für Versican Proteine (Vcan)

chondroitin sulfate proteoglycan 2a , chondroitin sulfate proteoglycan 2b , dermacan , chondroitin sulfate proteoglycan 2 (versican) , chondroitin sulfate proteoglycan 2 , versican , versican core protein-like , chondroitin sulfate proteoglycan core protein 2 , glial hyaluronate-binding protein , large fibroblast proteoglycan , versican core protein , versican proteoglycan , PG-M core protein , Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) , heart defect , GHAP , PG-M , proteoglycan

116993 Danio rerio
323465 Danio rerio
461766 Pan troglodytes
100101672 Xenopus (Silurana) tropicalis
445009 Canis lupus familiaris
100442387 Pongo abelii
100604867 Nomascus leucogenys
1462 Homo sapiens
13003 Mus musculus
114122 Rattus norvegicus
282662 Bos taurus
395565 Gallus gallus
488922 Canis lupus familiaris
397328 Sus scrofa
100727549 Cavia porcellus
100008666 Oryctolagus cuniculus
100294605 Ovis aries
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