Syndecan 2 Proteine (SDC2)

Auf finden Sie aktuell 11 Syndecan 2 (SDC2) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Syndecan 2 Antikörper (68) und Syndecan 2 Kits (15) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 99 Syndecan 2 Produkte verfügbar.
4833414L08Rik, AA960457, cb440, CD362, HSPG, Hspg1, Synd2, syndecan-2, zgc:103676
alle Proteine anzeigen Gen GeneID UniProt
SDC2 6383 P34741
SDC2 15529 P43407
SDC2 25615 P34900

Syndecan 2 Proteine (SDC2) nach Spezies

Weitere Proteine zu Syndecan 2 Interaktionspartnern

Zebrafish Syndecan 2 (SDC2) Interaktionspartner

  1. Results uncover a novel Sdc2-Tbx16-Fgf2 (zeige FGF2 Proteine) pathway that regulates epithelial cell morphogenesis.

  2. We show here that sdc2,sdc3 (zeige SDC3 Proteine) and sdc4 (zeige SDC4 Proteine) are expressed in the zebrafish embryonic brain during the major period of axon growth. These genes show differing expression patterns in the brain which provides putative insights into their functional specificity.

  3. Syndecan-2 is essential for angiogenic sprouting during zebrafish development

  4. Data show that syndecan 2 expressed in the extra-embryonic yolk syncytial layer acts locally at the YSL-embryo interface to direct organ primordia migration, and is required for fibronectin (zeige FN1 Proteine) and laminin matrix assembly throughout the embryo.

Human Syndecan 2 (SDC2) Interaktionspartner

  1. data suggest that syndecan-2 induces extracellular shedding of E-cadherin (zeige CDH1 Proteine) and supports the acquisition of a fibroblast-like morphology by regulating MMP-7 (zeige MMP7 Proteine) expression in a colon cancer cell line

  2. SDC2 is overexpressed in Leri's pleonosteosis. The minor allele of a missense SDC2 variant, p.Ser71Thr, could confer protection against systemic sclerosis.

  3. In this review we considered the function of syndecan-2, the structure of syndecan-2 and its role in the formation of amyloid plaques.

  4. HIV matrix protein p17 (zeige PDE6D Proteine) is pro-fibrogenic through its interactions both with CXCR2 (zeige CXCR2 Proteine) and syndecan-2 on activated HSCs

  5. The results demonstrate the importance of PDZ-binding domain of syndecan-2 for controlling LFA-1 (zeige ITGAL Proteine) affinity and cell adhesion.

  6. SDC2 expression was higher in skin melnaoma cells. It enhanced tyrosinase activity by increasing the membrane and melanosome localization of protein kinase CbetaII. UVB-induced up-regulation was required for UVB-induced melanin synthesis.

  7. syndecan 2 shows no changes associated to histological grade of Prostate cancer

  8. RhoA (zeige RHOA Proteine), but not RhoC (zeige RHOC Proteine) was shown to be essential for the anchored phenotype of breast carcinoma cells that accompanied siRNA-mediated loss of syndecan-2.

  9. RKIP (zeige PEBP1 Proteine), LOX (zeige LOX Proteine) and SDC2 are coordinately regulated and collectively encompass a prognostic signature for metastasis-free survival in ER-negative breast cancer patients

  10. Taken together, these data suggest that IL-1alpha regulates extracellular domain shedding of syndecan-2 through regulation of the MAP kinase (zeige MAPK1 Proteine)-mediated MMP-7 (zeige MMP7 Proteine) expression in colon cancer cells.

Mouse (Murine) Syndecan 2 (SDC2) Interaktionspartner

  1. Syndecan-2 expression is upregulated in colonic epithelia of mice with DSS (zeige PMP22 Proteine)-induced colitis via FOXO3 (zeige FOXO3 Proteine) activation.

  2. In mouse melanoma cells, siRNA-mediated knockdown of syndecan-2 was associated with reduced melanin synthesis, whereas overexpression of syndecan-2 increased melanin synthesis.

  3. The N-terminal growth-factor-like domain of amyloid-beta precursor protein is necessary for protein-receptor binding, whereas the E2-domain mediates interaction with membrane-anchored syndecan 2 and glypican 1 (zeige GPC1 Proteine).

  4. The repression of syndecan-2 by Wnt (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine)/TCF (zeige HNF4A Proteine) signaling contributes to the resistance of osteosarcoma cells to doxorubicin.

  5. MC1R (zeige MSHR Proteine) regulates melanoma cell migration via inhibition of syndecan-2 expression.

  6. Sarm1 (zeige SARM1 Proteine), a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphogenesis.

  7. RGD-independent cell adhesion via a tissue transglutaminase (zeige TGM2 Proteine) 2 (zeige TGM2 Proteine)-fibronectin (zeige FN1 Proteine) matrix promotes fibronectin (zeige FN1 Proteine) fibril deposition and requires syndecan-4 (zeige SDC4 Proteine)/2 and {alpha}5{beta}1 integrin co-signaling.

  8. The role of syndecan-2 in regulation of actin-cytoskeletal organization of Lewis lung carcinoma-derived metastatic clones.

  9. Syndecan-2 mRNA transcripts are expressed by reactive astrocytes in the region surrounding the necrotic brain tissue, exhibiting peak levels at day 7 after cryo-injury.

  10. HSPG and LRP (zeige LRP1 Proteine) together participate in VLDL clearance by means of a synergistic relationship.

Syndecan 2 (SDC2) Protein Überblick

Protein Überblick

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.

Alternative names and synonyms associated with Syndecan 2 (SDC2)

  • syndecan 2 (sdc2)
  • syndecan 2 (SDC2)
  • syndecan 2 (LOC100224966)
  • syndecan 2 (Sdc2)
  • 4833414L08Rik Protein
  • AA960457 Protein
  • cb440 Protein
  • CD362 Protein
  • HSPG Protein
  • Hspg1 Protein
  • Synd2 Protein
  • syndecan-2 Protein
  • zgc:103676 Protein

Bezeichner auf Proteinebene für Syndecan 2 Proteine (SDC2)

syndecan-2 , syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) , syndecan 2 , cell surface-associated heparan sulfate proteoglycan 1 , fibroglycan , heparan sulfate proteoglycan 1, cell surface-associated , heparan sulfate proteoglycan core protein , syndecan proteoglycan 2 , HSPG , heparan sulfate proteoglycan 1, cell surface-associated (fibroglycan) , Ryudocan/syndecan 2 , SYND2

282667 Danio rerio
374102 Gallus gallus
477945 Canis lupus familiaris
549917 Xenopus (Silurana) tropicalis
100224966 Taeniopygia guttata
6383 Homo sapiens
15529 Mus musculus
25615 Rattus norvegicus
615785 Bos taurus
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