Keratocan Proteine (KERA)

Keratocan Proteine (KERA)
Auf finden Sie aktuell 7 Keratocan (KERA) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Keratocan Antikörper (49) und Keratocan Kits (16) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 75 Keratocan Produkte verfügbar.
CNA2, KERA, si:dkeyp-38g8.3, SLRR2B, zgc:136259
alle Proteine anzeigen Gen GeneID UniProt
KERA 16545 O35367
Ratte KERA KERA 314771  
KERA 11081 O60938

Weitere Synonyme anzeigen

Keratocan Proteine (KERA) nach Spezies

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Am meisten referenzierte Keratocan Proteine

  1. Human KERA Protein expressed in Wheat germ - ABIN1308536 : Zhang, Mao, Schwend, Littlechild, Conrad: Resistance of corneal RFUVA–cross-linked collagens and small leucine-rich proteoglycans to degradation by matrix metalloproteinases. in Investigative ophthalmology & visual science 2013 (PubMed)
    Zeige alle 2 Referenzen für 1308536

Weitere Proteine zu Keratocan Interaktionspartnern

Zebrafish Keratocan (KERA) Interaktionspartner

  1. Data indicate that mammalian keratocan is conserved in zebrafish in terms of gene structure, expression pattern, and promoter function.

Mouse (Murine) Keratocan (KERA) Interaktionspartner

  1. rare variant in KERA was identified in a large kindred with premature atherosclerosis

  2. our results demonstrate the expression of keratocan by osteoblast lineage cells and its ability to modulate osteoblast function.

  3. Keratocan plays a unique role in maintaining the appropriate corneal shape to ensure normal vision

  4. Keratocan-deficient mice have corneal collagen fibrils with significantly larger diameters than those in wild-type mice, and increased centre-to-centre spacing of the fibrils.

  5. lumican (zeige LUM Proteine) has a novel regulatory role in keratocan expression at the transcriptional level

  6. lumican (zeige LUM Proteine) and keratocan core proteins bind the CXC chemokine (zeige CXCL12 Proteine) KC during a corneal inflammatory response, indicating that corneal KSPGs mediate neutrophil recruitment to the cornea by regulating chemokine (zeige CCL1 Proteine) gradient formation.

Human Keratocan (KERA) Interaktionspartner

  1. The mutation that we report here leads to the deletion of a conserved amino acid (p.Phe125del) from the third LRR motif of the keratocan protein, which might lead to an abnormal tertiary structure of the protein, thereby leading to the disease.

  2. a novel KERA variant, p.(Ile225Thr), was detected that segregates with Cornea plana in the homozygous form.

  3. Corneal endothelial disorders were found with compound mutations in KERA

  4. rare variant in KERA was identified in a large kindred with premature atherosclerosis

  5. Linkage and haplotype analyses identified 12q21.33 as a locus for posterior amorphous corneal dystrophy. However, no mutations were identified in the candidate genes (KERA, LUM (zeige LUM Proteine), DCN (zeige DCN Proteine), EPYC (zeige EPYC Proteine)) within this region.

  6. KERA mutation is associated with autosomal recessive cornea plana

  7. This is the first report of the identification of a mutation within KERA in a family of Hispanic origin with autosomal recessive cornea plana.

  8. No evidence that endothelial dysfunction and germline mutation of lumican and keratocan genes participate in the etiology of subepithelial corneal haze.

  9. Specific for mutation in KERA, the ophthalmic phenotype of recessive cornea plana does not significantly vary with different KERA mutations.

  10. In addition, no pathogenic sequence variations were found in DCN (zeige DCN Proteine), DSPG3 (zeige EPYC Proteine), LUM (zeige LUM Proteine), PITX2 (zeige PITX2 Proteine) and FOXC1 (zeige FOXC1 Proteine), which have also been implicated in corneal and anterior segment dysgenesis.

Rabbit Keratocan (KERA) Interaktionspartner

  1. FGF-2 (zeige FGF2 Proteine)- and TGF-beta1 (zeige TGFB1 Proteine)-activation of JNK (zeige MAPK8 Proteine) signaling pathway may be partly responsible for the downregulation of keratocan and lumican (zeige LUM Proteine) expression in activated corneal keratocytes observed during corneal stromal wound healing.

Keratocan (KERA) Protein Überblick

Protein Überblick

May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.

Alternative names and synonyms associated with Keratocan (KERA)

  • keratocan (KERA)
  • keratocan (kera)
  • keratocan (LOC100221424)
  • keratocan (Kera)
  • keratocan-like (LOC100157843)
  • CNA2 Protein
  • KERA Protein
  • si:dkeyp-38g8.3 Protein
  • SLRR2B Protein
  • zgc:136259 Protein

Bezeichner auf Proteinebene für Keratocan Proteine (KERA)

keratocan , keratocan-like , KTN , keratan sulfate proteoglycan keratocan , KSPG keratocan , corneal keratan sulfate proteoglycan 37A core protein

467089 Pan troglodytes
567017 Danio rerio
709743 Macaca mulatta
100221424 Taeniopygia guttata
100406618 Callithrix jacchus
100433816 Pongo abelii
100593731 Nomascus leucogenys
16545 Mus musculus
314771 Rattus norvegicus
11081 Homo sapiens
280785 Bos taurus
373995 Gallus gallus
482598 Canis lupus familiaris
100009022 Oryctolagus cuniculus
100157843 Sus scrofa
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