HMMR Proteine (HMMR)

Auf finden Sie aktuell 6 Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen HMMR Antikörper (109) und HMMR Kits (23) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 147 HMMR Produkte verfügbar.
AA386826, CD168, IHABP, RHAMM
alle Proteine anzeigen Gen GeneID UniProt
HMMR 15366 Q00547
HMMR 25460  
HMMR 3161 O75330

HMMR Proteine (HMMR) nach Spezies

Weitere Proteine zu HMMR Interaktionspartnern

Mouse (Murine) Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) Interaktionspartner

  1. RHAMM is not found on the cell-surface of embryonic stem cells, but it is required to maintain pluripotency and its dominant mechanism of action is through the modulation of signal transduction pathways at microtubules

  2. Hyaluronon acid activation of RHAMM significantly impacts smooth muscle cell-ECM (zeige MMRN1 Proteine) adhesive interactions and contributes to constrictive artery wall remodeling in mice.

  3. This study demonistrated that Rhamm expression in adult mouse subventricular zone and rostral migratory stream and in ischemic cortex.

  4. Overexpressing RHAMM was located intracellular and activated ERK1/2.

  5. Results suggest that the CD44 (zeige CD44 Proteine) and RHAMM receptors function on membrane lipid rafts during Cryptococcus neoformans invasion.

  6. RHAMM isoform B promotes liver metastasis in a mouse model of multistep tumorigenesis.

  7. intracellular RHAMM(Delta163) functions as an adaptor protein to control microtubule polymerization during interphase and mitosis as a result of localizing ERK1/2-MEK1 (zeige MAP2K1 Proteine) complexes to their tubulin (zeige TUBB Proteine)-associated substrates

  8. Gene deletion of Rhamm attenuates the formation of aggressive fibromatosis.

  9. CD44 (zeige CD44 Proteine) and RHAMM are molecularly redundant and have roles in a model of arthritis and inflammation

  10. Androgen receptor (zeige AR Proteine) regulates CD168 expression and signaling in prostate cancer

Human Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) Interaktionspartner

  1. spindle-associated (zeige HAUS1 Proteine) RHAMM as an intrinsic regulator of male germ cell fate and as a gatekeeper preventing initiation of testicular germ cell tumors (TGCT).

  2. Overexpression of the hyaluronan receptor HMMR in primary LUAD was associated with an inflammatory molecular signature and poor prognosis. Attenuating HMMR in LUAD cells diminished their ability to initiate lung tumors and distant metastases.

  3. The present study suggests that RHAMM is a novel beta-catenin (zeige CTNNB1 Proteine) intracellular binding partner, protecting beta-catenin (zeige CTNNB1 Proteine) from degradation and supporting the nuclear translocation of this key cellular mediator

  4. RHAMM expression identifies an aggressive subpopulation of tumor budding cells and is an independent adverse prognostic factor for colorectal cancer patients.

  5. a causative link between altered function of AURKA-HMMR-TPX2-TUBG1 and breast carcinogenesis in BRCA1/2 mutation carriers

  6. Identify RHAMM as a critical regulator of TPX2 (zeige TPX2 Proteine) location/ Aurora kinase A (zeige AURKA Proteine) signaling and suggest that RHAMM ensures bipolar spindle assembly and mitotic progression through the integration of biochemical and structural pathways.

  7. RHAMM might be a promising marker to identify early stage (nodal negative) patients at risk for dismal survival, who may benefit from specific adjuvant therapies.

  8. analysis of the role of growth factors in Hyaluronan/RHAMM interactions in mesenchymal tumor pathogenesis [review]

  9. Case Report: identify patient with cervical cancer expressing three HMMR mRNA variants.

  10. RHAMM may be implicated in severe ocular surface inflammation affecting the upper tarsal conjunctiva.

HMMR Protein Überblick

Protein Überblick

The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Alternative names and synonyms associated with HMMR

  • hyaluronan mediated motility receptor (RHAMM) (Hmmr)
  • hyaluronan-mediated motility receptor (RHAMM) (HMMR)
  • AA386826 Protein
  • CD168 Protein
  • IHABP Protein
  • RHAMM Protein

Bezeichner auf Proteinebene für HMMR

hyaluronan mediated motility receptor , intracellular hyaluronic acid-binding protein , receptor for hyaluronan-mediated motility , hyaluronan-mediated motility receptor

15366 Mus musculus
25460 Rattus norvegicus
3161 Homo sapiens
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