Brevican Proteine (BCAN)

Brevican Proteine (BCAN)
Auf finden Sie aktuell 6 Brevican (BCAN) Proteine von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Brevican Antikörper (87) und Brevican Kits (30) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 127 Brevican Produkte verfügbar.
ALPBRE, BCAN, BEHAB, CSPG7, fi32a12, wu:fi32a12, Xbcan
alle Proteine anzeigen Gen GeneID UniProt
BCAN 12032 Q61361
Ratte BCAN BCAN 25393 P55068
BCAN 63827 Q96GW7

Weitere Synonyme anzeigen

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Mouse (Murine) Brevican (BCAN) Interaktionspartner

  1. The extracellular matrix molecule brevican is an integral component of the machinery mediating fast synaptic transmission at the calyx of Held

  2. This study provided evidence that the brevican modulates synaptogenesis and long-term synapse stability. The mutant neurons display reduced frequencies of mEPSCs and mIPSCs.

  3. these results imply that Bral2 (zeige HAPLN4 Proteine)-brevican interaction may play a key role in synaptic stabilization and the structural integrity of brain perineuronal nets

  4. defective brevican processing observed in amyloid beta-bearing mice may contribute to deficient neural plasticity

  5. Results indicate that reactive gliosis differs between the spinal cord dorsal root entry zone and dorsal column and that Brevican and Versican (zeige Vcan Proteine) may participate in the inhibitory properties of the dorsal root entry zone.

  6. Brevican is not essential for learning and memory, but plays a role in long-term potentiation in mice

  7. Brevican and the ADAMTS (zeige ADAMTS1 Proteine)-cleaved fragment of brevican were most broadly distributed in neuropil in the brain.

  8. The proteoglycan (zeige Vcan Proteine) brevican binds to fibronectin (zeige FN1 Proteine) after proteolytic cleavage and promotes glioma cell motility

  9. This study show that brevican plays a crucial role in determining the specialization of the hyaluronan-binding nodal matrix assemblies in large diameter nodes.

Human Brevican (BCAN) Interaktionspartner

  1. Data indicate that median methylation levels of BCAN, HOXD1 (zeige HOXD1 Proteine), KCTD8 (zeige KCTD8 Proteine), KLF11 (zeige KLF11 Proteine), NXPH1 (zeige NXPH1 Proteine), POU4F1 (zeige POU4F1 Proteine), SIM1 (zeige SIM1 Proteine), and TCF7L1 (zeige TCF3 Proteine) were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis.

  2. High Brevican is associated with the invasive phenotype of low-grade astrocytoma.

  3. Authors describe the expression of BEHAB/brevican in human brain and characterize two novel glioma-specific isoforms which are generated by differential glycosylation and are absent from normal adult brain and other neuropathologies.

  4. These results demonstrate for the first time that ADAMTS-5 (zeige ADAMTS5 Proteine) is capable of degrading brevican and is overexpressed in glioblastoma cells, and suggest that ADAMTS-5 (zeige ADAMTS5 Proteine) may play a role in glioma cell invasion through the cleavage of brevican.

  5. The proteoglycan (zeige Vcan Proteine) brevican binds to fibronectin (zeige FN1 Proteine) after proteolytic cleavage and promotes glioma cell motility

Brevican (BCAN) Protein Überblick

Protein Überblick

This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with Brevican (BCAN)

  • brevican (bcan)
  • brevican (BCAN)
  • brain enriched hyaluronan binding protein (BEHAB)
  • brevican (Bcan)
  • ALPBRE Protein
  • BCAN Protein
  • BEHAB Protein
  • CSPG7 Protein
  • fi32a12 Protein
  • wu:fi32a12 Protein
  • Xbcan Protein

Bezeichner auf Proteinebene für Brevican Proteine (BCAN)

brevican core protein , brevican , brevican core protein-like , brevican soluble core protein , Brevican core protein , brain-enriched hyaluronan-binding protein , BEHAB , brevican (brain specific proteoglycan in the aggrecan family) , chondroitin sulfate proteoglycan 7 , chondroitin sulfate proteoglycan BEHAB , chondroitin sulfate proteoglycan BEHAB/brevican

334113 Danio rerio
457401 Pan troglodytes
100064356 Equus caballus
100456431 Pongo abelii
398229 Xenopus laevis
100582450 Nomascus leucogenys
727695 Felis catus
12032 Mus musculus
25393 Rattus norvegicus
63827 Homo sapiens
281019 Bos taurus
100339573 Oryctolagus cuniculus
100714598 Cavia porcellus
612102 Canis lupus familiaris
425976 Gallus gallus
101105963 Ovis aries
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