Pancreatic Polypeptide Proteine (PPY)

Pancreatic Polypeptide Proteine (PPY)
Auf finden Sie aktuell 10 Pancreatic Polypeptide (PPY) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Pancreatic Polypeptide Antikörper (150) und Pancreatic Polypeptide Kits (52) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 243 Pancreatic Polypeptide Produkte verfügbar.
alle Proteine anzeigen Gen GeneID UniProt
PPY 5539 P01298
PPY 24677 P06303
PPY 19064 P10601

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Human Pancreatic Polypeptide (PPY) Interaktionspartner

  1. GIP (zeige GIP Proteine) and pancreatic polypeptide plasma concentrations are lower in pancreatic cancer irrespective of the degree of glucose intolerance as compared to Type 2 diabetic patients and healthy controls.

  2. These data demonstrate glucose-regulated secretion of PP and its effects on glucagon (zeige GCG Proteine) release through PPYR1 (zeige PPYR1 Proteine) receptors expressed by alpha-cells.

  3. Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor (zeige PPYR1 Proteine) binding pocket.

  4. The diagnostic accuracy of the tumor markers CgA (zeige CGA Proteine), PP, and glucagon (zeige GCG Proteine) for pancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1 is low.

  5. These findings underscore the important role of the NPY (zeige NPY Proteine)-Y receptor system at several levels of the gut (zeige GUSB Proteine)-brain axis in which NPY (zeige NPY Proteine), peptide yy and pancreatic polypeptide operate both as neural and endocrine messengers--{REVIEW}

  6. Pancreatic polypeptide (and peptide tyrosine-tyrosine) increases in obese woman on caloric restriction following high protein liquid meals compared to high carbohydrate liquid meals.

  7. Data suggest that beta-cell function improves in overweight subjects with type 2 diabetes who lose weight by dieting; this change is associated with a decrease in PPY secretion (i.e., plasma PPY is decreased).

  8. Self-association of PPY with phospholipid micelles addressed the delivery issues of the peptide for diabetes treatment.

  9. Women with bulimia nervosa have significantly lower fasting and postprandial serum concentrations of pancreatic polypeptide (and GLP-1 (zeige GCG Proteine)) than control subjects.

  10. Distribution of pancreatic polypeptide and peptide YY

Mouse (Murine) Pancreatic Polypeptide (PPY) Interaktionspartner

  1. These data demonstrate glucose-regulated secretion of PP and its effects on glucagon (zeige GCG Proteine) release through PPYR1 (zeige PPYR1 Proteine) receptors expressed by alpha-cells.

  2. PP-initiated signaling through Npy6r in vasoactive intestinal peptide (zeige Vip PLURAL_@44953@) neurons regulates the growth hormone (zeige GH1 PLURAL_@44953@) axis and body composition.

  3. investigated the role of metalloendopeptidases in PYY(3-36) degradation and determined whether modulation of these enzymes enhanced PYY(3-36) plasma levels and bioactivity in vivo.

  4. Pancreatic polypeptide enhances colonic contractile activity and fecal output through neuropeptide Y (zeige NPY Proteine) Y(4) receptor, and a neuropeptide Y (zeige NPY Proteine) Y(4) receptor agonist might offer a novel therapeutic approach to ameliorate constipation.

  5. Roles of pancreatic polypeptide in regulation of food intake

  6. Pancreatic polypeptide may influence food intake, energy metabolism, and the expression of hypothalamic peptides and gastric ghrelin (zeige GHRL Proteine).

  7. Increased circulating cholecystokinin (zeige CCK Proteine) contributes to anorexia and anxiety behavior in mice overexpressing Ppy.

  8. In adult mice, the misexpression of Arx, rather than its overexpression, promotes a conversion of beta cells into glucagon (zeige GCG Proteine)- or PP-producing cells in vivo.

  9. 67.74% A-cells (glucagon (zeige GCG Proteine)-secreting cells) had PP (pancreatic polypeptide) immunoreactivity, 70.92% PP-cells contained glucagon (zeige GCG Proteine) immunoreactivity with immunofluorescence double staining

Pancreatic Polypeptide (PPY) Protein Überblick

Protein Überblick

This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products\; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.

Alternative names and synonyms associated with Pancreatic Polypeptide (PPY)

  • pancreatic polypeptide (PPY)
  • pancreatic polypeptide (Ppy)
  • pancreatic polypeptide (LOC100357679)
  • AV061413 Protein
  • IGSPP Protein
  • PNP Protein
  • PP Protein
  • PPY Protein

Bezeichner auf Proteinebene für Pancreatic Polypeptide Proteine (PPY)

pancreatic polypeptide , PP , pancreatic polypeptide Y , pancreatic prohormone , prepro-PP (prepropancreatic polypeptide) , Pancreatic prohormone percursor , panceatic polypeptide , pancreatic hormone , seminalplasmin , Pancreatic prohormone

739802 Pan troglodytes
5539 Homo sapiens
397272 Sus scrofa
280900 Bos taurus
24677 Rattus norvegicus
19064 Mus musculus
490944 Canis lupus familiaris
100357679 Oryctolagus cuniculus
101096772 Felis catus
395564 Gallus gallus
100135605 Cavia porcellus
443280 Ovis aries
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