anti-RICTOR (RICTOR) Antikörper

anti-RPTOR Independent Companion of MTOR, Complex 2 Antikörper (RICTOR)
Auf finden Sie aktuell 193 RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RICTOR Kits (5) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 209 RICTOR Produkte verfügbar.
4921505C17Rik, 6030405M08Rik, AVO3, AW492497, D530039E11Rik, Fyb, mAVO3, PIA
Alle Antikörper anzeigen Gen GeneID UniProt
RICTOR 253260 Q6R327
RICTOR 78757 Q6QI06
RICTOR 310131  

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Meistgesuchte Reaktivitäten zu anti-RICTOR (RICTOR) Antikörper

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anti-Human RICTOR Antikörper:

anti-Mouse (Murine) RICTOR Antikörper:

anti-Rat (Rattus) RICTOR Antikörper:

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Am meisten referenzierte anti-RICTOR Antikörper

  1. Human Polyclonal RICTOR Primary Antibody für IP, WB - ABIN152042 : Hresko, Mueckler: mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes. in The Journal of biological chemistry 2005 (PubMed)
    Zeige alle 33 Referenzen für 152042

  2. Human Polyclonal RICTOR Primary Antibody für FACS, ICC - ABIN152043 : Jindra, Jin, Rozengurt, Reed: HLA class I antibody-mediated endothelial cell proliferation via the mTOR pathway. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Zeige alle 17 Referenzen für 152043

  3. Human Polyclonal RICTOR Primary Antibody für EIA, IHC (p) - ABIN359477 : Jacinto, Facchinetti, Liu, Soto, Wei, Jung, Huang, Qin, Su: SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. in Cell 2006 (PubMed)
    Zeige alle 4 Referenzen für 359477

  4. Human Polyclonal RICTOR Primary Antibody für EIA, IHC (p) - ABIN359480 : Pearce, Huang, Boudeau, Paw?owski, Wullschleger, Deak, Ibrahim, Gourlay, Magnuson, Alessi: Identification of Protor as a novel Rictor-binding component of mTOR complex-2. in The Biochemical journal 2007 (PubMed)
    Zeige alle 3 Referenzen für 359480

  5. Human Polyclonal RICTOR Primary Antibody für IHC, ELISA - ABIN185390 : Sarbassov, Ali, Kim, Guertin, Latek, Erdjument-Bromage, Tempst, Sabatini: Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. in Current biology : CB 2004 (PubMed)
    Zeige alle 2 Referenzen für 185390

  6. Human Monoclonal RICTOR Primary Antibody für ELISA, FACS - ABIN4350528 : Loganathan, Kandala, Gupta, Srivastava: Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model. in PLoS ONE 2012 (PubMed)
    Zeige alle 2 Referenzen für 4350528

  7. Human Polyclonal RICTOR Primary Antibody für IHC (p), WB - ABIN391384 : Gao, Wu, Spencer, Johnson, Bazer et al.: Select nutrients in the ovine uterine lumen. VI. Expression of FK506-binding protein 12-rapamycin complex-associated protein 1 (FRAP1) and regulators and effectors of mTORC1 and mTORC2 complexes in ... in Biology of reproduction 2009 (PubMed)
    Zeige alle 2 Referenzen für 391384

  8. Human Monoclonal RICTOR Primary Antibody für ICC, FACS - ABIN969382 : Yang, Inoki, Ikenoue, Guan: Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity. in Genes & development 2006 (PubMed)

Weitere Antikörper gegen RICTOR Interaktionspartner

Human RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) Interaktionspartner

  1. miR (zeige MLXIP Antikörper)-153 downregulation could be one important reason of Rictor upregulation and mTORC2 (zeige CRTC2 Antikörper) over-activation in glioma cells. Further, miR (zeige MLXIP Antikörper)-153-induced anti-glioma cell activity is possibly via downregulating Rictor.

  2. These results point to an increase in total and phosphorylated Akt (zeige AKT1 Antikörper) in high-grade gliomas and to a possible role of RICTOR in proliferations of high-grade glioblastomas cells.

  3. Hgh mTOR (zeige FRAP1 Antikörper) activity and Rictor overexpression could be markers of a bad prognosis. Combined phosphoprotein and Rictor/Raptor (zeige RPTOR Antikörper) expression evaluation revealed even stronger statistical correlation with prognosis.

  4. In this study we began by validating the expression of four main mTOR (zeige FRAP1 Antikörper) pathway components, mTOR (zeige FRAP1 Antikörper), DEPTOR (zeige DEPTOR Antikörper), rictor and raptor (zeige RPTOR Antikörper), at gene and protein level in in vitro models of endometrioid (MDAH2774) and clear cell (SKOV3) ovarian cancer

  5. Based on univariate and multivariate Cox (zeige COX8A Antikörper) proportional hazards regression analysis, RICTOR-positive expression, AJCC staging III or IV and nodal metastasis are prognostic factors and the former two are independent risk factors for esophageal squamous cell carcinoma.

  6. Taken together, our results suggest that the proinflammatory cytokine TNFalpha (zeige TNF Antikörper) promotes the expression of Rictor through the NF-kappaB (zeige NFKB1 Antikörper) pathway in renal cell carcinoma (zeige MOK Antikörper).

  7. RICTOR amplification may define a novel and unique molecular subset of patients with lung cancer who may benefit from treatment with mTORC1/2 inhibitors.

  8. Data show that rapamycin-insensitive companion of mTOR protein (RICTOR) plays a central role in phosphatidylinositol 3-kinase (PI3K (zeige PIK3CA Antikörper))/proto-oncogene (zeige RAB1A Antikörper) protein c (zeige PROC Antikörper)-akt (AKT (zeige AKT1 Antikörper)) pathway in melanocytes and its deregulation could be involved in melanoma development.

  9. Mdm20 (zeige NAA25 Antikörper) acts as a novel regulator of Rictor, thereby controlling mTORC2 (zeige CRTC2 Antikörper) activity, and leading to the activation of PKCalphaS657 and FoxO1 (zeige FOXO1 Antikörper).

  10. RICTOR/MTORC2 (zeige CRTC2 Antikörper)-AKT (zeige AKT1 Antikörper) can integrate convergent hormonal and metabolic signals to provide coordinated and sensitive regulation of hepatic FOXO1 (zeige FOXO1 Antikörper)-target gene expression.

Mouse (Murine) RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) Interaktionspartner

  1. our present findings highlighted a pivotal regulatory axis of Rictor-FoxO3a (zeige FOXO3 Antikörper) in maintaining quiescence and the stemness of LSCs.

  2. These findings reveal a novel functional pathway important for age-related bone loss and support for miR (zeige MLXIP Antikörper)-218 and Rictor as potential targets for therapeutic intervention for age-related osteoporosis treatment.

  3. this study shows that Rictor is required for NKT (zeige CTSL1 Antikörper)-17 cell development and normal iNKT-cell cytolytic function

  4. data suggest that Rictor/mTORC2 (zeige CRTC2 Antikörper) controls an amino acid-sensitive checkpoint that allows T cells to determine whether the microenvironment contains sufficient resources for daughter cell generation.

  5. Loss of DNMT3B (zeige DNMT3B Antikörper) results in hypomethylation of the miR (zeige MLXIP Antikörper)-196b promoter and increased miR (zeige MLXIP Antikörper)-196b expression, which directly targets the mTORC2 (zeige CRTC2 Antikörper) component Rictor.

  6. Rictor in the limb mesenchymal lineage is required for the normal response to the anti-sclerostin (zeige SOST Antikörper) therapy in both bone formation and resorption.

  7. Low RICTOR expression was detected in quiescent, confluent mouse aortic endothelial cells, whereas high doses of FGF2 (zeige FGF2 Antikörper) induced high RICTOR expression that was associated with strong mTORC2 (zeige CRTC2 Antikörper)-specific protein kinase (zeige CDK7 Antikörper) Ca and AKT (zeige AKT1 Antikörper) phosphorylation

  8. analysis of mTORC2 (zeige CRTC2 Antikörper) components mTOR (zeige FRAP1 Antikörper), Rictor and mSin1 reveals diurnal variation in mouse perivascular adipose tissue

  9. Adipose tissue mTORC2 (zeige CRTC2 Antikörper) regulates via Rictor ChREBP (zeige MLXIPL Antikörper)-driven de novo lipogenesis and hepatic glucose metabolism.

  10. Rictor is essential for the generation of type II IFN-dependent antiviral and antiproliferative responses and that it controls the generation of type II IFN-suppressive effects on normal and malignant hematopoiesis

RICTOR Antigen-Profil

Beschreibung des Gens

RICTOR and MTOR (FRAP1\; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004

Alternative names and synonyms associated with RICTOR

  • RPTOR independent companion of MTOR, complex 2 (RICTOR) Antikörper
  • rapamycin-insensitive companion of mTOR (LOC100357138) Antikörper
  • RPTOR independent companion of MTOR, complex 2 (Rictor) Antikörper
  • 4921505C17Rik Antikörper
  • 6030405M08Rik Antikörper
  • AVO3 Antikörper
  • AW492497 Antikörper
  • D530039E11Rik Antikörper
  • Fyb Antikörper
  • mAVO3 Antikörper
  • PIA Antikörper

Bezeichner auf Proteinebene für RICTOR

rapamycin-insensitive companion of mTOR , AVO3 homolog , TORC2-specific protein AVO3 , hAVO3 , pianissimo , mAVO3 , protein pianissimo , FYN binding protein , rapamycin insensitive companion of mTOR

694915 Macaca mulatta
100357138 Oryctolagus cuniculus
253260 Homo sapiens
78757 Mus musculus
479356 Canis lupus familiaris
310131 Rattus norvegicus
527459 Bos taurus
100519575 Sus scrofa
100715888 Cavia porcellus
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