anti-DAB2IP (DAB2IP) Antikörper

Bezeichnung:
anti-DAB2 Interacting Protein Antikörper (DAB2IP)
Auf www.antikoerper-online.de finden Sie aktuell 27 DAB2 Interacting Protein (DAB2IP) Antikörper von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen DAB2IP Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 31 DAB2IP Produkte verfügbar.
Synonyme:
2310011D08Rik, AF9Q34, AI480459, AIP-1, Aip1, dab2ip, DIP1/2, mKIAA1743, wu:fc08b07, wu:fk62h05

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anti-Human DAB2IP Antikörper:

anti-Rat (Rattus) DAB2IP Antikörper:

anti-Mouse (Murine) DAB2IP Antikörper:

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Am meisten referenzierte anti-DAB2IP Antikörper

  1. Human Polyclonal DAB2IP Primary Antibody für IP, WB - ABIN440620 : Cook, Kim, Terao, Gotoh, Higuchi: Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer. in Cell death & disease 2012 (PubMed)

Weitere Antikörper gegen DAB2IP Interaktionspartner

Human DAB2 Interacting Protein (DAB2IP) Interaktionspartner

  1. Down-regulation of DAB2IP correlated negatively with hnRNPK (zeige HNRNPK Antikörper) and MMP2 (zeige MMP2 Antikörper) expressions in CRC (zeige CALR Antikörper) tissues. In conclusion, our study elucidates a novel mechanism of the DAB2IP/hnRNPK (zeige HNRNPK Antikörper)/MMP2 (zeige MMP2 Antikörper) axis in the regulation of CRC (zeige CALR Antikörper) invasion and metastasis, which may be a potential therapeutic target.

  2. DAB2IP appears to be a new prognostic/predictive marker for metastatic renal cell cancer (mRCC) patients, and its function provides a new insight into the molecular mechanisms of drug resistance to mTOR (zeige FRAP1 Antikörper) inhibitors, which also can be used to develop new strategies to overcome drug-resistant mRCC.

  3. Along with the reduction of ovarian cancer-2/disabled homolog 2 (DOC-2 (zeige DAB2 Antikörper)/DAB2) interactive protein (DAB2IP) expression, EGR-1 (zeige EGR1 Antikörper) gene was upregulated in FI-treated cells. On the other hand, downregulation of EGR-1 (zeige EGR1 Antikörper) gene expression sensitized radioresistant cells to IR accompanied by DAB2IP overexpression and STAT3 (zeige STAT3 Antikörper) inactivation. In addition, NF-kappaB (zeige NFKB1 Antikörper) inhibitor, BAY11-7082 enhanced resistant cells' radiosensitivity and chemos...

  4. Our findings demonstrate a novel function of DAB2IP in the maintenance of KT-MT structure and SAC (zeige ADCY10 Antikörper) regulation during mitosis which is essential for chromosomal stability.

  5. DAB2IP may be involved in forming acquired radioresistance in PC3 (zeige PCSK1 Antikörper) cells. DAB2IP-deficient cells are resistant to low and high-LET radiation using different mechanisms. DAB2IP-deficient cells are resistant to both gamma-rays and alpha-particles.

  6. our data provided evidence to verify that miR (zeige MLXIP Antikörper)-92b was able to directly target DAB2IP, a well-known tumor suppressor, and inhibit epithelialmesenchymal transition of bladder cancer cells

  7. DAB2IP protein levels are higher in bladder cancer than in upper tract urothelial carcinoma and in superficial bladder cancer

  8. Infiltrating T cells regulate ERbeta (zeige ESR2 Antikörper)/DAB2IP signals in renal cell carcinoma (zeige MOK Antikörper).

  9. Pretreatment biopsy analysis of DAB2IP identifies subpopulation of high-risk prostate cancer patients with worse survival following radiation therapy

  10. Data show that colorectal cancer (CRC (zeige CALR Antikörper)) patients with lower DAB2 interaction protein (DAB2IP) expression had shorter overall survival time.

Mouse (Murine) DAB2 Interacting Protein (DAB2IP) Interaktionspartner

  1. DAB2IP loss reprograms intracellular signal transduction and anti-apoptotic gene expression, which potentiates prostate cancer cell survival from androgen deprivation therapy-induced cell death.

  2. Germ cell-specific or Sertoli cell-specific deletion of Aip1 gene each led to significant defects in germ cell migration after postnatal day 4 or 5, accompanied by elevated levels of actin filaments (F-actin) in the affected cells.

  3. Cor1B, Cof1 and AIP1 work in concert through a temporally ordered pathway to induce highly efficient severing and disassembly of actin filaments.

  4. results suggest that Dab2IP plays an important role in the migration and positioning of a subpopulation of later-born (layers II-IV) neurons, likely through the regulation of Rap1 and integrin signaling.

  5. Our data reveal that AIP1 (zeige PDCD6IP Antikörper), by inhibiting VEGFR2 (zeige KDR Antikörper)-dependent signaling in tumor niche, suppresses tumor EMT (zeige ITK Antikörper) switch, tumor angiogenesis, and tumor premetastatic niche formation to limit tumor growth and metastasis.

  6. AIP1 (zeige PDCD6IP Antikörper) was elevated in the brain of AD Tg2576 mice. Abeta1-42 treatment induced the interaction of AIP1 (zeige PDCD6IP Antikörper) and ASK1 (zeige MAP3K5 Antikörper), which led to dissociation of ASK1 (zeige MAP3K5 Antikörper) and 14-3-3 (zeige YWHAQ Antikörper).

  7. site-specific methylation of mDab2ip gene during cerebellar development may play a role in inclusion of exon 5, resulting in a Dab2ip transcript variant that encodes a full pleckstrin (zeige PLEK Antikörper) homology (PH) domain.

  8. Study showed that DAB2IP can be functionally inactivated by physical interaction with mutant p53 (zeige TP53 Antikörper) proteins with implications for the response of cancer cells to inflammatory cytokines.

  9. DAB2IP is a unique intrinsic androgen receptor (zeige AR Antikörper) modulator in normal cells, and likely can be further developed into a therapeutic agent for rpostate cancer.

  10. AIP1 (zeige PDCD6IP Antikörper) knockouts have reduced retinal angiogenesis. Vascular endothelial cell (but not neuronal)-specific deletion of AIP1 (zeige PDCD6IP Antikörper) causes similar defects. AIP1 (zeige PDCD6IP Antikörper) via miR (zeige MLXIP Antikörper)-1236 increases VEGFR-3 (zeige FLT4 Antikörper) expression and binds it, enhancing endocytosis and stability.

DAB2IP Antigen-Profil

Beschreibung des Gens

DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005

Alternative names and synonyms associated with DAB2IP

  • DAB2 interacting protein (DAB2IP) Antikörper
  • DAB2 interacting protein b (dab2ipb) Antikörper
  • DAB2 interacting protein (dab2ip) Antikörper
  • DAB2 interacting protein (Dab2ip) Antikörper
  • disabled 2 interacting protein (Dab2ip) Antikörper
  • 2310011D08Rik Antikörper
  • AF9Q34 Antikörper
  • AI480459 Antikörper
  • AIP-1 Antikörper
  • Aip1 Antikörper
  • dab2ip Antikörper
  • DIP1/2 Antikörper
  • mKIAA1743 Antikörper
  • wu:fc08b07 Antikörper
  • wu:fk62h05 Antikörper

Bezeichner auf Proteinebene für DAB2IP

DAB2 interacting protein , ASK-interacting protein 1 , ASK1-interacting protein 1 , DAB2 interaction protein , DAB2-interacting protein , DOC-2/DAB-2 interactive protein , DOC-2/DAB2 interactive protein , disabled homolog 2-interacting protein , nGAP-like protein , apoptosis signal-regulating kinase 1-interacting protein 1 , disabled homolog 2 interacting protein , DOC2/DAB2 interactive protein , disabled 2 interacting protein long form

GENE ID SPEZIES
100071680 Equus caballus
417117 Gallus gallus
558237 Danio rerio
699080 Macaca mulatta
100081752 Ornithorhynchus anatinus
100145038 Xenopus (Silurana) tropicalis
100591971 Nomascus leucogenys
153090 Homo sapiens
491356 Canis lupus familiaris
100286868 Sus scrofa
541268 Bos taurus
192126 Rattus norvegicus
100719421 Cavia porcellus
69601 Mus musculus
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