RAD23A Proteine (RAD23A)

Bezeichnung:
RAD23 Homolog A (S. Cerevisiae) Proteine (RAD23A)
Auf www.antikoerper-online.de finden Sie aktuell 7 RAD23 Homolog A (S. Cerevisiae) (RAD23A) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RAD23A Antikörper (94) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 105 RAD23A Produkte verfügbar.
Synonyme:
2310040P19Rik, AL024030, HHR23A, HR23A, mHR23A, RAD23A, wu:fe11h06, zgc:92001
alle Proteine anzeigen Gen GeneID UniProt
RAD23A 5886 P54725
Ratte RAD23A RAD23A 361381  
RAD23A 19358  

Weitere Synonyme anzeigen

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Weitere Proteine zu RAD23A Interaktionspartnern

Human RAD23 Homolog A (S. Cerevisiae) (RAD23A) Interaktionspartner

  1. Data indicate that HR23A protein-depleted cells exhibit enhanced autophagy when treated with DNA-damaging agents.

  2. HR23A role in DNA reapair, in protein degradation and stability, tumorigenesis and neurodegenerative disorders [review]

  3. hHR23A associates with Chk1 (zeige CHEK1 Proteine) through its ubiquitin-associated domains, and knockdown of hHR23A increases and stabilizes the protein level of Chk1 (zeige CHEK1 Proteine) and its phosphorylation at S347.

  4. Here, we show that hHR23A utilizes both the UBA2 and XPCB domains to form a stable complex with Vpr, linking Vpr directly to cellular DNA repair pathways and their probable exploitation by the virus.

  5. this study identified RAD23A as a novel negative regulator of RIG-I (zeige DDX58 Proteine)/MDA5 (zeige IFIH1 Proteine) mediated anti-virus response.

  6. Determined is the three-dimensional structure of its ubiquitin-like (UbL) domain by X-ray crystallography.

  7. Vpr promotes hHR23A-mediated protein-ubiquitination, and down-regulation of hHR23A using RNAi significantly reduced viral replication in non-proliferating MAGI-CCR5 cells and primary macrophages

  8. involvement of rhp23, a Schizosaccharomyces pombe homolog of the human HHR23A and Saccharomyces cerevisiae RAD23 nucleotide excision repair genes, in cell cycle control and protein ubiquitination

  9. structures of the UBA domains of HHR23A reveal a conserved hydrophobic surface for protein-protein interactions

  10. the solution structures of the HHR23A Ubl domain

Mouse (Murine) RAD23 Homolog A (S. Cerevisiae) (RAD23A) Interaktionspartner

  1. the mammalian RAD23 proteins play a direct role in damage recognition by enhancing the binding of XPC (zeige XPC Proteine) to DNA damage in living cells in addition to stabilizing XPC (zeige XPC Proteine). RAD23 proteins rapidly dissociated from XPC (zeige XPC Proteine) upon binding to damaged DNA.

  2. analysis of mHR23A/B double-mutant cells showed that HR23 proteins function in nucleotide excision repair by governing xeroderma pigmentosum group C protein (zeige HNRNPC Proteine) stability via partial protection against proteasomal degradation

RAD23A Protein Überblick

Protein Überblick

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair. Proteins in this family have a modular domain structure consisting of an ubiquitin-like domain (UbL), ubiquitin-associated domain 1 (UbA1), XPC-binding domain and UbA2. The protein encoded by this gene plays an important role in nucleotide excision repair and also in delivery of polyubiquitinated proteins to the proteasome. Alternative splicing results in multiple transcript variants encoding multiple isoforms.

Alternative names and synonyms associated with RAD23A

  • RAD23 homolog Aa (S. cerevisiae) (rad23aa)
  • RAD23 homolog A (S. cerevisiae) (RAD23A)
  • RAD23 homolog A (S. cerevisiae) (Rad23a)
  • RAD23a homolog (S. cerevisiae) (Rad23a)
  • 2310040P19Rik Protein
  • AL024030 Protein
  • HHR23A Protein
  • HR23A Protein
  • mHR23A Protein
  • RAD23A Protein
  • wu:fe11h06 Protein
  • zgc:92001 Protein

Bezeichner auf Proteinebene für RAD23A

RAD23 homolog A , UV excision repair protein RAD23 homolog A , RAD23 homolog A (S. cerevisiae) , RAD23, yeast homolog, A

GENE ID SPEZIES
445284 Danio rerio
717979 Macaca mulatta
5886 Homo sapiens
484922 Canis lupus familiaris
361381 Rattus norvegicus
540564 Bos taurus
19358 Mus musculus
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