anti-NEIL2 (NEIL2) Antikörper

Bezeichnung:
anti-Nei Endonuclease VIII-Like 2 (E. Coli) Antikörper (NEIL2)
Auf www.antikoerper-online.de finden Sie aktuell 43 Nei Endonuclease VIII-Like 2 (E. Coli) (NEIL2) Antikörper von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NEIL2 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 59 NEIL2 Produkte verfügbar.
Synonyme:
Gm1212, NEH2, NEI2
Alle Antikörper anzeigen Gen GeneID UniProt
NEIL2 252969 Q969S2
NEIL2 382913  
NEIL2    

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anti-Human NEIL2 Antikörper:

anti-Mouse (Murine) NEIL2 Antikörper:

anti-Rat (Rattus) NEIL2 Antikörper:

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Am meisten referenzierte anti-NEIL2 Antikörper

  1. Human Polyclonal NEIL2 Primary Antibody für EIA, WB - ABIN953644 : Kinslow, El-Zein, Hill, Wickliffe, Abdel-Rahman: Single nucleotide polymorphisms 5' upstream the coding region of the NEIL2 gene influence gene transcription levels and alter levels of genetic damage. in Genes, chromosomes & cancer 2008 (PubMed)
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Weitere Antikörper gegen NEIL2 Interaktionspartner

Human Nei Endonuclease VIII-Like 2 (E. Coli) (NEIL2) Interaktionspartner

  1. The abnormal expressions of NEIL1 (zeige NEIL1 Antikörper), NEIL2, and NEIL3 (zeige NEIL3 Antikörper) are involved in cancer through their association with the somatic mutation load.

  2. NEIL1 (zeige NEIL1 Antikörper) and NEIL2 cooperate with TDG (zeige TDG Antikörper) during base excision: TDG (zeige TDG Antikörper) occupies the abasic site and is displaced by NEILs, which further process the baseless sugar, thereby stimulating TDG (zeige TDG Antikörper)-substrate turnover.

  3. Studied six SNP loci: (rs2279115 of BCL2 gene, rs804270 of NEIL2 gene, rs909253 of LTA gene, rs2294008 of PSCA gene, rs3765524 and rs10509670 of PLCE1 gene) to evaluate gastric cancer risk using magnetic nanoparticles and universal tagged arrays.

  4. The variability of potentially important functional polymorphic variants of the IFNG (zeige IFNG Antikörper), IFNGR2 (zeige IFNGR2 Antikörper) and NEIL2 genes was characterized in representatives of four ethnic groups living in the Siberian region.

  5. variant alleles in the NEIL2 (rs804270), APE1 (zeige APEX1 Antikörper) (rs2275008), CYP2E1 (zeige CYP2E1 Antikörper) (rs2031920) and MDM2 (zeige MDM2 Antikörper) (rs2279744) SNPs may independently influence susceptibility to gastric cancer in a Northern Jiangsu Chinese population.

  6. data strongly suggest that decreased repair of oxidative DNA base lesions due to an impaired NEIL2 expression in non-smokers exposed to SSS would lead to accumulation of mutations in genomic DNA of lung cells over time

  7. CSB (zeige ERCC6 Antikörper) protein stimulates NEIL2 DNA glycosylase activity

  8. Results suggest that the decreased DNA repair capacity of the DNA glycosylase NEIL2 R257L variant can induce mutations that lead to lung cancer development.

  9. the critical role of NEIL2 and PNKP (zeige PNKP Antikörper) in maintenance of the mammalian mitochondrial genome.

  10. REG4 (zeige REG4 Antikörper), BIRC5 (zeige BIRC5 Antikörper) and NEIL2 genes might have a role in the sensitivity of cancer patients to radiotherapy

Mouse (Murine) Nei Endonuclease VIII-Like 2 (E. Coli) (NEIL2) Interaktionspartner

  1. NEIL2 plays an important role in long term genomic maintenance

  2. the beta2/beta3 loop where Lys50 is located in NEIL2 is important for DNA binding, presumably lies next to a phosphate-binding site, and may represent a target for regulation of the enzyme activity.

  3. NEIL1 (zeige NEIL1 Antikörper) and NEIL2 are essential in the recognition of oxidized lesions arising from 8-oxoG and may play important roles in the repair of DNA damage induced by carcinogenic metals.

  4. Recombinant human DNA Polymerase beta (zeige POLB Antikörper) and recombinant mpise NEIL2 associated with microtubules in situ and in vivo.

  5. Keap1 (zeige KEAP1 Antikörper) recruits NEH2 through binding to ETGE and DLG (zeige DLG4 Antikörper) motifs.

  6. Results suggest a role for NEIL1 (zeige NEIL1 Antikörper) and 2 as backup deoxyribo-5'-phosphate lyases in mammalian cells.

NEIL2 Antigen-Profil

Beschreibung des Gens

NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002

Alternative names and synonyms associated with NEIL2

  • nei endonuclease VIII-like 2 (E. coli) (NEIL2) Antikörper
  • nei like 2 (E. coli) (Neil2) Antikörper
  • Gm1212 Antikörper
  • NEH2 Antikörper
  • NEI2 Antikörper

Bezeichner auf Proteinebene für NEIL2

DNA glycosylase/AP lyase Neil2 , DNA-(apurinic or apyrimidinic site) lyase Neil2 , endonuclease 8-like 2 , endonuclease VIII-like 2 , nei homolog 2 , nei like 2 , nei-like protein 2 , NEH2 , Endonuclease VIII-like 2

GENE ID SPEZIES
252969 Homo sapiens
444987 Bos taurus
100172638 Pongo abelii
382913 Mus musculus
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